Physical Sciences and Mathematics Commons^™

A Hybrid Lipid Membrane Coating “Shape-Locks” Silver Nanoparticles To Prevent Surface Oxidation And Silver Ion Dissolution, Thomas J. Miesen, Arek M. Engstrom, Dane C. Frost, Ramya Ajjarapu, Rohan Ajjarapu, Citlali Nieves Lira, Marilyn R. Mackiewicz

Chemistry Faculty Publications and Presentations

The controlled synthesis of stable silver nanoparticles (AgNPs), that do not undergo surface oxidation and Ag⁺ ion dissolution, continues to be a major challenge. Here the synthesis of robust hybrid lipid-coated AgNPs, comprised of L-α-phosphatidylcholine (PC) membranes anchored by a stoichiometric amount of long-chained hydrophobic thiols and sodium oleate (SOA) as hydrophobic binding partners, that do not undergo surface oxidation and Ag+ ion dissolution, is described. UV-Visible (UV-Vis) spectroscopy, transmission electron microscopy (TEM), and inductively coupled plasma mass spectrometry (ICP-MS) demonstrate that in the presence of strong oxidants, such as potassium cyanide (KCN), the hybrid lipid-coated AgNPs are stable …