Physical Sciences and Mathematics Commons^™

Investigation Of The Sources And Sinks Of Atmospheric Methane, Christopher Lee Butenhoff

Dissertations and Theses

The work presented here represents a number of independent studies that investigated various components of the CH₄ budget, namely the sources and sinks. We used a chemical-tracer model and created unique long-term time series of atmospheric CH₄, carbon monoxide (CO), molecular hydrogen (H₂), and methylchloroform (CH₃CCl₃) measurements at marine background air to derive histories of atmospheric hydroxyl radical (OH) - the main chemical oxidant of CH₄, biomass burning - an important source of CH₄ in the tropics, and emissions of CH₄ from rice paddies - one of …

S-Nitrosothiols: Formation, Decomposition, Reactivity And Possible Physiological Effects, Moshood Kayode Morakinyo

Dissertations and Theses

Three biologically-active aminothiols cysteamine (CA), DL-cysteine (CYSH) and DL-homocysteine, were studied in this thesis. These aminothiols react with nitrous acid (HNO₂), prepared in situ, to produce S-nitrosothiols (RSNOs): S-nitrosocyteamine (CANO), S-nitrosocysteine (CYSNO) and S-nitrosohomocysteine (HCYSNO). They also react with S-nitrosoglutathione (GSNO) and S-nitroso-N-acetylpenicillamine (SNAP) through a transnitrosation reaction to produce their corresponding RSNOs. A detailed kinetics and mechanistic study on the formation of these RSNOs and their subsequent decomposition to release nitric oxide (NO) were studied.

For all three aminothiols the stoichiometry of their reaction with nitrous acid is strictly 1:1 with the formation of one mole …