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Development Of Solid Phase Microextraction Methods For Contraband Drugs, Vangielynn Cruz Tersol
Development Of Solid Phase Microextraction Methods For Contraband Drugs, Vangielynn Cruz Tersol
Chemistry & Biochemistry Theses & Dissertations
The objective of this study is to develop analytical methods for studying contraband drugs at nanogram levels and to demonstrate the utility of the methods. A method which combines solid phase microextraction with ion mobility spectrometry (SPME-IMS) was developed. The SPME-IMS method was used as a rapid screening tool in studying the chemistry of cocaine HCI, heroin HCI, and heroin freebase on surfaces. The total time for sample preparation, reaction, and analysis is approximately seven minutes. Another method that was developed is one that combines solid phase microextraction with gas chromatography (SPME-GC) for the quantitative analysis of cocaine freebase and …