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Full-Text Articles in Physical Sciences and Mathematics

An Examination Of The Association Of Selected Toxic Metals With Total And Central Obesity Indices: Nhanes 99-02, Miguel A. Padilla, Mai Elobeid, Douglas M. Ruden, David B. Allison Jan 2010

An Examination Of The Association Of Selected Toxic Metals With Total And Central Obesity Indices: Nhanes 99-02, Miguel A. Padilla, Mai Elobeid, Douglas M. Ruden, David B. Allison

Psychology Faculty Publications

It is conceivable that toxic metals contribute to obesity by influencing various aspects of metabolism, such as by substituting for essential micronutrients and vital metals, or by inducing oxidative stress. Deficiency of the essential metal zinc decreases adiposity in humans and rodent models, whereas deficiencies of chromium, copper, iron, and magnesium increases adiposity. This study utilized the NHANES 99-02 data to explore the association between waist circumference and body mass index with the body burdens of selected toxic metals (barium, cadmium, cobalt, cesium, molybdenum, lead, antimony, thallium, and tungsten). Some of the associations were significant direct relationships (barium and thallium), …


Endocrine Disruptors And Obesity: An Examination Of Selected Persistent Organic Pollutants In The Nhanes 1999-2002 Data, Mai A. Elobeid, Miguel A. Padilla, David W. Brock, Douglas M. Ruden, David B. Allison Jan 2010

Endocrine Disruptors And Obesity: An Examination Of Selected Persistent Organic Pollutants In The Nhanes 1999-2002 Data, Mai A. Elobeid, Miguel A. Padilla, David W. Brock, Douglas M. Ruden, David B. Allison

Psychology Faculty Publications

Recent evidence suggests that endocrine disrupting chemicals (EDCs) may cause perturbations in endogenous hormonal regulation that predispose to weight gain. Using data from NHANES (1999-2002), we investigated the association between body mass index (BMI), waist circumference (WC) and selected persistent organic pollutants (POPs) via multiple linear regressions. Consistent interaction was found between gender, ln oxychlordane and ln p,p' DDT. Also, we found an association between WC and ln oxychlordane and ln hpcdd in subjects with detectable levels of POPs, whereas an association between WC and ln p,p' DDT was observed in all subjects. Furthermore, ln Ocdd showed an increase with …