Physical Sciences and Mathematics Commons^™

Tracing And Segmentation Of Molecular Patterns In 3-Dimensional Cryo-Et/Em Density Maps Through Algorithmic Image Processing And Deep Learning-Based Techniques, Salim Sazzed

Computer Science Theses & Dissertations

Understanding the structures of biological macromolecules is highly important as they are closely associated with cellular functionalities. Comprehending the precise organization of actin filaments is crucial because they form the dynamic cytoskeleton, which offers structural support to cells and connects the cell’s interior with its surroundings. However, determining the precise organization of actin filaments is challenging due to the poor quality of cryo-electron tomography (cryo-ET) images, which suffer from low signal-to-noise (SNR) ratios and the presence of missing wedge, as well as diverse shape characteristics of actin filaments. To address these formidable challenges, the primary component of this dissertation focuses …

Assessing The Prevalence And Archival Rate Of Uris To Git Hosting Platforms In Scholarly Publications, Emily Escamilla

Computer Science Theses & Dissertations

The definition of scholarly content has expanded to include the data and source code that contribute to a publication. While major archiving efforts to preserve conventional scholarly content, typically in PDFs (e.g., LOCKSS, CLOCKSS, Portico), are underway, no analogous effort has yet emerged to preserve the data and code referenced in those PDFs, particularly the scholarly code hosted online on Git Hosting Platforms (GHPs). Similarly, Software Heritage is working to archive public source code, but there is value in archiving the surrounding ephemera that provide important context to the code while maintaining their original URIs. In current implementations, source code …

Towards Intelligent Runtime Framework For Distributed Heterogeneous Systems, Polykarpos Thomadakis

Computer Science Theses & Dissertations

Scientific applications strive for increased memory and computing performance, requiring massive amounts of data and time to produce results. Applications utilize large-scale, parallel computing platforms with advanced architectures to accommodate their needs. However, developing performance-portable applications for modern, heterogeneous platforms requires lots of effort and expertise in both the application and systems domains. This is more relevant for unstructured applications whose workflow is not statically predictable due to their heavily data-dependent nature. One possible solution for this problem is the introduction of an intelligent Domain-Specific Language (iDSL) that transparently helps to maintain correctness, hides the idiosyncrasies of lowlevel hardware, and …

Inverse Mappers For Qcd Global Analysis, Manal Almaeen

Computer Science Theses & Dissertations

Inverse problems – using measured observations to determine unknown parameters – are well motivated but challenging in many scientific problems. Mapping parameters to observables is a well-posed problem with unique solutions, and therefore can be solved with differential equations or linear algebra solvers. However, the inverse problem requires backward mapping from observable to parameter space, which is often nonunique. Consequently, solving inverse problems is ill-posed and a far more challenging computational problem.

Our motivated application in this dissertation is the inverse problems in nuclear physics that characterize the internal structure of the hadrons. We first present a machine learning framework …

Supporting Account-Based Queries For Archived Instagram Posts, Himarsha R. Jayanetti

Computer Science Theses & Dissertations

Social media has become one of the primary modes of communication in recent times, with popular platforms such as Facebook, Twitter, and Instagram leading the way. Despite its popularity, Instagram has not received as much attention in academic research compared to Facebook and Twitter, and its significant role in contemporary society is often overlooked. Web archives are making efforts to preserve social media content despite the challenges posed by the dynamic nature of these sites. The goal of our research is to facilitate the easy discovery of archived copies, or mementos, of all posts belonging to a specific Instagram account …