Physical Sciences and Mathematics Commons^™

Data Mining Of Tetraloop-Tetraloop Receptors In Rna Xml Files, Sinan Ramazanoglu

Theses

RNA (Ribonucleic acid) Motifs are tertiary structures that play an important role in the folding mechanism of the RNA molecule. The overall function of a RNA Motif depends on its specific bp (base pairs) sequence that constitutes the secondary structure. Data mining is a novel method in both discovering potential tertiary structures within DNA (Deoxyribonucleic acid), RNA, and protein molecules and storing the information in databases. The RNA Motif of interest is the tetraloop-tetraloop receptor, which is composed of a highly conserved 11 nt (nucleotide) sequence and a tetraloop with the generic form of GNRA (where N = any base …

Analysis Of Gene Expression Data Using Expressionist 3.1 And Genespring 4.2, Indu Shrivastava

Theses

The purpose of this study was to determine the differences in the gene expression analysis methods of two data mining tools, Expressionistic^TM 3.1 and GeneSpring^TM 4.2 with focus on basic statistical analysis and clustering algorithms. The data for this analysis was derived from the hybridization of Rattus norvegicus RNA to the Affymetrix RG34A GeneChip. This analysis was derived from experiments designed to identify changes in gene expression patterns that were induced in vivo by an experimental treatment.

The tools were found to be comparable with respect to the list of statistically significant genes that were up-regulated by more …

A Tool For Phylogenetic Data Cleaning And Searching, Viswanath Neelavalli

Theses

Data collection and cleaning is a very important part of an elaborate Data Mining System. 'TreeBASE' is a relational database of phylogenetic information at the Harvard University with a keyword based searching interface. 'TreeSearch' is a Structure based search engine implemented at NJIT that can be used for searching phylogenetic data. Phylogenetic trees are extracted from the flat-file database at Harvard University, available at {ftp://herbaria.harvard.edu/pub/piel/Data/files/}. There is huge amount of information present in the files about the trees and the data matrices from which the trees are generated. The search tool implemented at NJIT is interested in using the string …