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Full-Text Articles in Physical Sciences and Mathematics

Role Of Microtubules In Budding Yeast Cytokinesis, Su Young Park Jan 2008

Role Of Microtubules In Budding Yeast Cytokinesis, Su Young Park

Masters Theses

"Cytokinesis is an important step to finish cell cycle events and separate into two daughter cells. This event is driven by actomyosin ring contraction. In budding yeast, the mitotic exit network (MEN) controls completion of ana/telophase by signaling events. Bub2 is a mitotic exit network regulator and binds to Tem1p which is an important component in MEN. Mad2 is a component of a separate spindle checkpoint. Mad2 dependent pathway prevents the metaphase to anaphase transition under spindle damage. Because yeast cells have cell walls, septum formation follows actin ring contraction. Here it was investigated how microtubule defects affect cytokinesis in …


Validation Of An Nsp-Based (Negative Selection Pattern) Gene Family Identification Strategy, Ronald L. Frank, Cyriac Kandoth, Fikret Erçal Jan 2008

Validation Of An Nsp-Based (Negative Selection Pattern) Gene Family Identification Strategy, Ronald L. Frank, Cyriac Kandoth, Fikret Erçal

Biological Sciences Faculty Research & Creative Works

Background: Gene family identification from ESTs can be a valuable resource for analysis of genome evolution but presents unique challenges in organisms for which the entire genome is not yet sequenced. We have developed a novel gene family identification method based on negative selection patterns (NSP) between family members to screen EST-generated contigs. This strategy was tested on five known gene families in Arabidopsis to see if individual paralogs could be identified with accuracy from EST data alone when compared to the actual gene sequences in this fully sequenced genome. Results: The NSP method uniquely identified family members in all …


Polyaniline Nanofiber-Based Gas Sensors, Zhe-Fei Li, Frank D. Blum, Massimo F. Bertino, Chang-Soo Kim Jan 2008

Polyaniline Nanofiber-Based Gas Sensors, Zhe-Fei Li, Frank D. Blum, Massimo F. Bertino, Chang-Soo Kim

Chemistry Faculty Research & Creative Works

There has been recent interest in conducting polymers that have very promising chemical and electrical applications. Some of these polymers have shown great potential for use in sensors.1 Polyaniline is one particular example of a prospective material. In our laboratory, we have studied the synthesis of polyaniline nanofibers. We have carried out one-pot syntheses to obtain polyaniline nanofibers in aqueous solutions where the polymerization was influenced by γ-radiation2 or UV-radiation.3 This polymer can also be patterned with an appropriate photo mask. In our present report, polyaniline nanofiber thin film sensors have been fabricated in one step by employing UV-irradiation and …


The Identification And Characterization Of Phenylalanine Ammonia-Lyase Gene Family Members In Glycine Max, Erin Kathleen Pringle Jan 2008

The Identification And Characterization Of Phenylalanine Ammonia-Lyase Gene Family Members In Glycine Max, Erin Kathleen Pringle

Masters Theses

"Gene families are collections of genes with similar functions. Studying gene families is important for understanding the evolution of genes and manipulating genes. Phenylalanine ammonia-lyase (PAL) is an enzyme found in plants. It catalyzes the deamination of phenylalanine to produce cinnamic acid. Genes for PAL have been identified in many different plant species. This project used the known sequence for the PAL1 gene in Glycine max to find other PAL genes in Glycine max"--Abstract, page iii.