Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Physical Sciences and Mathematics
Improving Protein Succinylation Sites Prediction Using Embeddings From Protein Language Model, Suresh Pokharel, Pawel Pratyush, Michael Heinzinger, Robert H. Newman, Dukka Kc
Improving Protein Succinylation Sites Prediction Using Embeddings From Protein Language Model, Suresh Pokharel, Pawel Pratyush, Michael Heinzinger, Robert H. Newman, Dukka Kc
Michigan Tech Publications
Protein succinylation is an important post-translational modification (PTM) responsible for many vital metabolic activities in cells, including cellular respiration, regulation, and repair. Here, we present a novel approach that combines features from supervised word embedding with embedding from a protein language model called ProtT5-XL-UniRef50 (hereafter termed, ProtT5) in a deep learning framework to predict protein succinylation sites. To our knowledge, this is one of the first attempts to employ embedding from a pre-trained protein language model to predict protein succinylation sites. The proposed model, dubbed LMSuccSite, achieves state-of-the-art results compared to existing methods, with performance scores of 0.36, 0.79, 0.79 …
Deep-Learning-Incorporated Augmented Reality Application For Engineering Lab Training, John Estrada, Sidike Paheding, Xiaoli Yang, Quamar Niyaz
Deep-Learning-Incorporated Augmented Reality Application For Engineering Lab Training, John Estrada, Sidike Paheding, Xiaoli Yang, Quamar Niyaz
Michigan Tech Publications
Deep learning (DL) algorithms have achieved significantly high performance in object detection tasks. At the same time, augmented reality (AR) techniques are transforming the ways that we work and connect with people. With the increasing popularity of online and hybrid learning, we propose a new framework for improving students’ learning experiences with electrical engineering lab equipment by incorporating the abovementioned technologies. The DL powered automatic object detection component integrated into the AR application is designed to recognize equipment such as multimeter, oscilloscope, wave generator, and power supply. A deep neural network model, namely MobileNet-SSD v2, is implemented for equipment detection …