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Physical Sciences and Mathematics Commons

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Articles 1 - 9 of 9

Full-Text Articles in Physical Sciences and Mathematics

Inelastic Electron Tunneling Via Molecular Vibrations In Single-Molecule Transistors, L H. Yu, Z K. Keane, Jacob W. Ciszek, L Cheng, M P. Stewart, J M. Tour, D Natelson Dec 2004

Inelastic Electron Tunneling Via Molecular Vibrations In Single-Molecule Transistors, L H. Yu, Z K. Keane, Jacob W. Ciszek, L Cheng, M P. Stewart, J M. Tour, D Natelson

Chemistry: Faculty Publications and Other Works

In single-molecule transistors, we observe inelastic cotunneling features that correspond energetically to vibrational excitations of the molecule, as determined by Raman and infrared spectroscopy. This is a form of inelastic electron tunneling spectroscopy of single molecules, with the transistor geometry allowing in situ tuning of the electronic states via a gate electrode. The vibrational features shift and change shape as the electronic levels are tuned near resonance, indicating significant modification of the vibrational states. When the molecule contains an unpaired electron, we also observe vibrational satellite features around the Kondo resonance.


Azaadamantane Benzamide 5-Ht4 Agonists: Gastrointestinal Prokinetic Sc-54750, Daniel Becker, Daniel L. Flynn, Robert L. Shone, Gary Gullikson Nov 2004

Azaadamantane Benzamide 5-Ht4 Agonists: Gastrointestinal Prokinetic Sc-54750, Daniel Becker, Daniel L. Flynn, Robert L. Shone, Gary Gullikson

Chemistry: Faculty Publications and Other Works

Azaadamantanone 1 was converted to a series of aminoazaadamantane benzamides 9a–d, which were profiled for serotonin receptor activity. Aminomethylazaadamantane SC-54750 is a potent 5-HT4 agonist and 5-HT3 antagonist with in vivo efficacy in gastroparesis models and also inhibits cisplatin-induced emesis.


Gentoo Linux: The Next Generation Of Linux, George K. Thiruvathukal Sep 2004

Gentoo Linux: The Next Generation Of Linux, George K. Thiruvathukal

Computer Science: Faculty Publications and Other Works

One of the reasons scientific programmers love Linux is its less-is-more philosophy. We can configure it to be anything from a desktop replacement with USB port support to a blade in a large SMP compute engine to a powerful Web server. Although Linux's market penetration in these various sectors remains to be seen, plenty of people are pumping resources into the Linux world. In this article, I?ll explain why Gentoo Linux (www.gentoolinux.org) is a good choice for scientists, and how its structure gives us the flexibility and ease of management we need.


Reply To “Comment On Gravitational Slingshot,” By C. L. Cook [Am. J. Phys. 73 (4), 363 (2005)], Asim Gangopadhyaya, Asim Gangopadhyaya, Robert Cacioppo, John J. Dykla Aug 2004

Reply To “Comment On Gravitational Slingshot,” By C. L. Cook [Am. J. Phys. 73 (4), 363 (2005)], Asim Gangopadhyaya, Asim Gangopadhyaya, Robert Cacioppo, John J. Dykla

Physics: Faculty Publications and Other Works

No abstract provided.


Plone And Content Management, George K. Thiruvathukal, Konstantin Läufer Jul 2004

Plone And Content Management, George K. Thiruvathukal, Konstantin Läufer

Computer Science: Faculty Publications and Other Works

In this column, the authors look at Plone, which they feel is one of the best content management systems available today. Even better, it?s distributed under a free open-source license: the cost of getting started is only limited to the time you have available to set up the software on a server. Plone is written in Python and uses the Zope application server infrastructure; it runs on most modern operating systems. The authors have even set it up at Loyola University Chicago in the Department of Computer Science. Besides being two faculty members who rely on Plone to host all …


Bridgehead-Methyl Analog Of Sc-53116 As A 5-Ht4 Agonist, Daniel Becker, Daniel L. Flynn, Clara I. Villamil Jun 2004

Bridgehead-Methyl Analog Of Sc-53116 As A 5-Ht4 Agonist, Daniel Becker, Daniel L. Flynn, Clara I. Villamil

Chemistry: Faculty Publications and Other Works

Pyrrolizidine benzamide (±)-2, the bridgehead-methyl analog of SC-53116, was prepared and evaluated for 5-HT4 agonism activity in the rat tunica muscularis (TMM) mucosae assay. Compound (±)-2 has an EC50 of 449 nM in the TMM assay, as compared to 23 nM for SC-53116, and 66 nM for the racemate of SC-53116.


Gravitational Slingshot , John J. Dykla, Robert Cacioppo, Asim Gangopadhyaya Apr 2004

Gravitational Slingshot , John J. Dykla, Robert Cacioppo, Asim Gangopadhyaya

Physics: Faculty Publications and Other Works

The slingshot effect is an intriguing phenomenon that has been used effectively by NASA to send spacecraft to outer edges of the solar system. This phenomenon can be satisfactorily explained by Newtonian physics. However, if it is presented as a problem involving four-momentum conservation, the methods of relativistic kinematics easily lead to the conditions necessary for an accelerating as well as a retarding scenario. This problem provides an example that showcases the frequent utility of relativistic methods to analyze problems of Newtonian mechanics.


Natural Xml For Data Binding, Processing, And Persistence, George K. Thiruvathukal, Konstantin Läufer Mar 2004

Natural Xml For Data Binding, Processing, And Persistence, George K. Thiruvathukal, Konstantin Läufer

Computer Science: Faculty Publications and Other Works

The article explains what you need to do to incorporate XML directly into your computational science application. The exploration involves the use of a standard parser to automatically build object trees entirely from application-specific classes. This discussion very much focuses on object-oriented programming languages such as Java and Python, but it can work for non-object-oriented languages as well. The ideas in the article provide a glimpse into the Natural XML research project.


Xml In Computational Science, George K. Thiruvathukal Jan 2004

Xml In Computational Science, George K. Thiruvathukal

Computer Science: Faculty Publications and Other Works

In this first article in a series about XML in computational science, I present some background and lightweight examples of XML usage, describe some XML component frameworksalong with their purpose and applicability to computational science, and discuss some technical obstacles to overcome for the language to be taken seriously in computational science.