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Physical Sciences and Mathematics Commons™
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Full-Text Articles in Physical Sciences and Mathematics
Thermal Analysis In A Triple-Layered Skin Structure With Embedded Vasculature, Tumor, And Gold Nanoshells, Casey O. Orndorff
Thermal Analysis In A Triple-Layered Skin Structure With Embedded Vasculature, Tumor, And Gold Nanoshells, Casey O. Orndorff
Doctoral Dissertations
In hyperthermia skin cancer treatment, the objective is to control laser heating of the tumor (target temperatures of 42-46 °C) so that the temperatures of the normal tissue surrounding the tumor remains low enough not to damage the normal tissue. However, obtaining accurate temperature distributions in living tissue related to hyperthermia skin cancer treatment without using an intruding sensor is a challenge. The objective of this dissertation research is to develop a mathematical model that can accurately predict the temperature distribution in the tumor region and surrounding normal tissue induced by laser irradiation. The model is based on a modified …
A Numerical Method For Obtaining An Optimal Temperature Distribution In A Three-Dimensional Triple-Layered Skin Structure Embedded With Multi-Level Blood Vessels, Xingui Tang
Doctoral Dissertations
The research related to hyperthermia has stimulated a lot of interest in recent years because of its application in cancer treatment. When heating the tumor tissue, the crucial problem is keeping the temperature of the surrounding normal tissue below a certain threshold in order to avoid the damage to the normal tissue. Hence, it is important to obtain the temperature field of the entire region during the treatment. The objective of this dissertation is to develop a numerical method for obtaining an optimal temperature distribution in a 3D triple-layered skin structure embedded with multi-level blood vessels where the surface of …
Modeling Of The Inverse Heat -Conduction Problem With Application To Laser Chemical Vapor Deposition And Bioheat Transfer, Peng Zhen
Doctoral Dissertations
This dissertation consists of two parts. Part one deals with three-dimensional laser induced chemical vapor deposition (3D-LCVD), whereas part two deals with a Pennes model of a 3D skin structure. LCVD is an important technique in manufacturing complex micro-structures with high aspect ratio. In part one, a numerical model was developed for simulating kinetically-limited growth of an axisymmetric cylindrical rod by pre-specifying the surface temperature distribution required for growing the rod and then by obtaining optimized laser power that gives rise to the pre-specified temperature distribution. The temperature distribution at the surface of the rod was assumed to be at …