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Interplay Effects In Highly Modulated Stereotactic Body Radiation Therapy Lung Cases Treated With Volumetric Modulated Arc Therapy, Desmond Joseph Fernandez
Interplay Effects In Highly Modulated Stereotactic Body Radiation Therapy Lung Cases Treated With Volumetric Modulated Arc Therapy, Desmond Joseph Fernandez
LSU Master's Theses
Purpose: To evaluate the influence of tumor motion on dose delivery in highly modulated stereotactic body radiotherapy (SBRT) of lung cancer using volumetric modulated arc therapy (VMAT). Methods: 4D-CT imaging data of the quasar respiratory phantom were acquired, using a GE Lightspeed 16-slice CT scanner, while the phantom reproduced patient specific respiratory traces. Flattening filter-free (FFF) dual-arc VMAT treatment plans were created on the acquired images in Pinnacle3 treatment planning system. Each plan was generated with varying levels of complexity characterized by the modulation complexity score. Static and dynamic measurements were delivered to GafChromic EBT3 film inside the respiratory phantom …