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Articles 1 - 28 of 28
Full-Text Articles in Physical Sciences and Mathematics
Synthesis And Cellular Investigations Of The 131-Lysyl Derivative Of Chlorin E6, Stewart Wynn Humble
Synthesis And Cellular Investigations Of The 131-Lysyl Derivative Of Chlorin E6, Stewart Wynn Humble
Honors Theses
No abstract provided.
Investigation Of Electroosmotic Flow Dynamics And Reproducibility In Capillary Electrophoresis, Funda Kizilkaya
Investigation Of Electroosmotic Flow Dynamics And Reproducibility In Capillary Electrophoresis, Funda Kizilkaya
LSU Doctoral Dissertations
The goal of this dissertation is to investigate electroosmotic flow (EOF) and electric field dynamics during capillary electrophoresis (CE) experiments using methods based on periodic photobleaching of fluorophores added to the separation buffer at nanomolar concentrations. The methods provide time resolved EOF and local electric field information during an experiment, which can be applied to fundamental studies to provide better understanding of CE techniques. The potential of the EOF monitoring method to improve CE migration reproducibility was investigated in Chapter 2. The EOF monitoring method and four other methods from the literature were applied to the same electrophoretic separations, and …
Synthesis, Characterization, And Self-Assembly Of Porphyrins Conjugated To Superparamagnetic Colloidal Particles For Enhanced Photodynamic Therapy, Javoris Hollingsworth
Synthesis, Characterization, And Self-Assembly Of Porphyrins Conjugated To Superparamagnetic Colloidal Particles For Enhanced Photodynamic Therapy, Javoris Hollingsworth
LSU Doctoral Dissertations
Porphyrins and their derivatives are often used as photosensitizers in photodynamic therapy (PDT), which is a noninvasive antitumor treatment. The photochemical process for PDT involves exciting a photosensitizing agent with visible light, which induces cytotoxicity in the presence of oxygen as a result of forming reactive oxygen species (ROS). The ROS are the responsible components for invoking cell death and destruction of tumors. Although this mechanism is an effective cancer therapeutic, it still has many shortcomings. One major challenge of PDT concerns improving the tumor selectivity and specificity of photosensitizers because porphyrins have nonspecific affinity to tumor cells. The discussed …
Beta-Diketone And Beta-Ketoenamine Based Molecular Squares, Jackson Kiplagat Cherutoi
Beta-Diketone And Beta-Ketoenamine Based Molecular Squares, Jackson Kiplagat Cherutoi
LSU Doctoral Dissertations
Abstract This dissertation focuses on synthesis of β-diketone and β-ketoenamine ligands for molecular polygons. Previous work with the bis(β-diketone) m-pbaH2 showed that it can be converted to a copper molecular square, Cu4(m-pba)4, but its use in host-guest reactions was limited by its low solubility in most organic solvents. Accordingly, in the present work, the m-pbhxH2 ligand, with pentyl chains replacing the methyl groups in the β-diketone moieties of m-pbaH2, was successfully prepared beginning with 6-dodecyne. This ligand reacts with Cu2+ to make the molecular square Cu4(m-pbhx)4, which is soluble in a wider range of solvents. Host-guest reactions of Cu4(m-pbhx)4 with …
Synthesis, Cellular Studies, And Computational Analysis Of Porphyrin And Bodipy Conjugates With Affinity For Epidermal Growth Factor Receptor, Alecia Michelle Mccall
Synthesis, Cellular Studies, And Computational Analysis Of Porphyrin And Bodipy Conjugates With Affinity For Epidermal Growth Factor Receptor, Alecia Michelle Mccall
LSU Doctoral Dissertations
Chapter 1 is a description of the basic fundamental concepts of porphyrins and BODIPYs, (including synthetic methodologies), a general mechanism of the processes of EGFR, and computational concepts that are elaborated upon in future chapters. Chapter 2 is a discussion solely on the porphyrins that were synthesized to be used as fluorophores for EGFR-targeted conjugates, both peptidic and non-peptidic. The porphyrins were primarily synthesized via the Lindsey method as well as by O-alkylation of tetrahydroxy porphyrins. Synthesis of PEG linkages are discussed as well through three methodologies. Chapter 3 is a presentation of the synthesis, characterization, cellular studies, and computational …
Synthesis And Characterization Of Red And Near-Infrared Bodipy-Based Fluorophores For Various Biological Applications, Timsy Kaur Uppal
Synthesis And Characterization Of Red And Near-Infrared Bodipy-Based Fluorophores For Various Biological Applications, Timsy Kaur Uppal
LSU Doctoral Dissertations
ABSTRACT 4,4-Difluoro-3a,4a-diaza-s-indacene, better known as BODIPY® dyes, have attracted considerable attention due to their intriguing physicochemical and spectral properties, including high absorption coefficient, fluorescence quantum yield and good photochemical stability. Despite the recent progress achieved in this field, the synthesis of BODIPY derivatives that absorb and emit in the red- and NIR-region of the electromagnetic spectrum and their application to biomolecular targets, represents a long-standing challenge in BODIPY chemistry. This research work is therefore focused on the synthesis and characterization of red and NIR-emissive BODIPY-based fluorophores for various bioanalytical and biomedical applications. Chapter 1 of this dissertation represents a concise …
Design, Synthesis, Characterization, And Application Of Peptides As Different Medical Treatment, Krystal Renee Fontenot
Design, Synthesis, Characterization, And Application Of Peptides As Different Medical Treatment, Krystal Renee Fontenot
LSU Doctoral Dissertations
A peptide is defined, as a molecule that contains less than fifty amino acids; anything larger is a protein. Peptides are important molecules because they have diverse uses. Peptides were utilized in two ways: 1) Peptide bioconjugates containing a fluorescent porphyrin or phthalocyanine macrocycle were designed and investigated, with or without a PEG moiety for selective targeting of the epidermal growth factor receptor (EGFR). 2) Amyloid aggregating mitigating peptides (AAMPs) was synthesized and investigated containing polar amino acids, MiniPEGs, and/or ααAAs that have the ability to inhibit and disrupt Amyloid Beta (Aβ). The peptide bioconjugates containing a porphyrin or phthalocyanine …
Single-Molecule Detection Of Molecular Beacons Generated From Ldr On Thermoplastic Microfluidic Device For Bioanalysis, Zhiyong Peng
Single-Molecule Detection Of Molecular Beacons Generated From Ldr On Thermoplastic Microfluidic Device For Bioanalysis, Zhiyong Peng
LSU Doctoral Dissertations
Current clinical techniques for nucleic acid detection and analysis often involve PCR, lacking adequate specificity or sensitivity to meet the stringent requirements in certain applications. This research aims to develop an innovative molecular assay and the associated hardware to rapidly signal the presence of certain targets using reporter sequence found in their genome without requiring PCR. This assay coupled the sensitivity of single-pair fluorescence resonance energy transfer (spFRET) with the specificity of ligase detection reaction (LDR) to provide near real-time readout of target biomarkers. Heightened concerns on potential bioterrorism threats, such as rapid dissemination of pathogenic bacteria or viruses into …
Novel Nonresonant And Resonant Mechanisms Leading To The Breakdown Of The Franck-Condon Approximation In Photoionization, David Adam Hardy
Novel Nonresonant And Resonant Mechanisms Leading To The Breakdown Of The Franck-Condon Approximation In Photoionization, David Adam Hardy
LSU Doctoral Dissertations
This thesis attempts to answer the question of how electrons interact with a molecular framework prior to and during emission through photoionization. These studies interrogate several behaviors of allowed and forbidden photoelectron transitions such as shape resonances, non-resonant intrachannel vibronic coupling as a result of Cooper minima, and chemically-induced nonresonant coupling, all of which provide new insights into correlations between the electronic and molecular degrees of freedom. Research presented in this thesis utilizes high-resolution photoelectron spectroscopy, and undulator-based synchrotron radiation at the Advanced Light Source, a synchrotron radiation source in Berkeley, California. Data are collected from near threshold to several …
On The Synthesis, Characterization, And Magnetization Of Ln-M-X (Ln = Lanthanide; M = Ti-Cr, Cu, Mo, Pd; X = Al, Ga) Intermetallics, Michael James Kangas
On The Synthesis, Characterization, And Magnetization Of Ln-M-X (Ln = Lanthanide; M = Ti-Cr, Cu, Mo, Pd; X = Al, Ga) Intermetallics, Michael James Kangas
LSU Doctoral Dissertations
The focus of the research presented herein was to grow single crystals of Ln-M-X (Ln = lanthanide; M = Ti-Cr, Cu, Mo, Pd; X = Al, Ga) intermetallic compounds and to characterize their crystal structures and physical properties. Overall, the flux growth technique facilitated a detailed analysis of previously known structure-types (LnM2Al20 (Ln = La, Ce, Pr, Yb; M = Ti, V, Cr), Ln6M4Al43 (Ln = Gd, Yb; M = Cr, Mo), and Yb2Pd3Ga9), as well as the synthesis and characterization of new compounds (LnCrxGa3 (Ln = Ho, Er; x ~ 0.13), YbCr2Al20-xFex (x ~ 0.2), Ln(Cu,Al,Ga)13-x, and Ln2PdGa12 (Ln …
Development Of Innovative Stationary Phases For Chiral And Protein Separations In Open Tubular Capillary Electrochromatography, Leonard Moore, Jr.
Development Of Innovative Stationary Phases For Chiral And Protein Separations In Open Tubular Capillary Electrochromatography, Leonard Moore, Jr.
LSU Doctoral Dissertations
Protein biomarkers in bodily fluids can lead to an indication of the onset of a disease. Due to low abundance of the biomarker at early stages of the disease and other protein interferences, detection may be challenging. Therefore, in order to achieve more selective protein separations, the development of a novel stationary phase has been investigated. Moreover, novel methods to apply polysaccharides as stationary phases were developed for protein separations as well as chiral separations. The initial discussions in this dissertation commences with the use of novel zwitterionic lysine-based molecular micelles as a coating for open tubular capillary electrochromatography (OT-CEC) …
Syntheses And Characterization Of Water-Soluble Phythalocyanines For Diagnosis And Treatment Of Cancer, Benson Getenga Ongarora
Syntheses And Characterization Of Water-Soluble Phythalocyanines For Diagnosis And Treatment Of Cancer, Benson Getenga Ongarora
LSU Doctoral Dissertations
Ongarora, Benson Getenga, B.S., Moi University, 2005 Doctor of Philosophy, Fall Commencement, 2012 Major: Chemistry Syntheses and Characterization of Water-Soluble Phthalocyanines for Diagnosis and Treatment of Cancer Dissertation directed by Professor M.Graҫa H. Vicente Pages in dissertation, xi. Words in abstract, 251. ABSTRACT Chapter 1 describes the general properties of phthalocyanines, synthesis of metallo-phthalocyanines, their photophysical features and their uses. The concepts of PDT and targeted therapeutics are also introduced. Chapter 2 describes the syntheses, characterization, photophysical studies and biological evaluation of cationic phthalocyanines. The trimethylaminophenoxy substituted phthalocyanines were synthesized through statistical condensation method, which gave a statistical mixture of …
Detection And Characterization Of Environmentally Persistent Free Radicals (Epfrs) In Soils And Sediments From Superfund Sites, Albert Leo N. Dela Cruz
Detection And Characterization Of Environmentally Persistent Free Radicals (Epfrs) In Soils And Sediments From Superfund Sites, Albert Leo N. Dela Cruz
LSU Doctoral Dissertations
Environmentally persistent free radicals (EPFRs) from combustion-generated PM have been demonstrated to form via reactions of molecular precursors with redox-active transition metals at 150-500C thermal reactions in a few seconds reaction times. While ambient temperatures are much lower, soils/sediments contain similar transition metals, and reaction times of contaminants in soils/sediments are years, rather than seconds. This questions whether EPFRs could be formed at ambient temperatures in soils/sediments from Superfund sites that are contaminated with hazardous materials. Superfund soils contaminated with PCP from Georgia and Montana, and sediments contaminated with PAHs from Washington. Using EPR spectroscopy, EPFR concentrations and structural assignments …
Infrared Laser Ablation For Biological Mass Spectrometry, Fan Huang
Infrared Laser Ablation For Biological Mass Spectrometry, Fan Huang
LSU Doctoral Dissertations
Instrument and technique development and modeling of ionization methods using infrared (IR) laser desorption and ablation for mass spectrometry (MS) analysis of chemical and biochemical samples are described. Infrared lasers are highly efficient at sample removal and post-ablation ionization of materials removed by IR laser can be used to improve ionization efficiency. Fundamental studies of the physical processes in laser ablation mass spectrometry can help elucidate the mechanism. In this research, an infrared/ultraviolet two-laser matrix-assisted laser desorption ionization (MALDI) MS was developed for analysis of biomolecules. An infrared laser was used to ablate a mixture of analyte and matrix, and …
Investigations Into The Role Of Natural Organic Matter As An Interface Between Aquatic Organisms And Environmental Pollutants, Caroline Lillian Schneider
Investigations Into The Role Of Natural Organic Matter As An Interface Between Aquatic Organisms And Environmental Pollutants, Caroline Lillian Schneider
LSU Doctoral Dissertations
The impact of the continuous pollution of freshwater environments by multiple pollutants has not been well-studied. The goal of this research was to evaluate the toxicity of several modern pollutants in a model environment. The prokaryotic, unicellular blue-green algae Synechocystis WT6803 and the eukaryotic, multicellular Utterbackia imbecillis mussel larvae were studied along with Suwannee River natural organic matter (NOM). The toxicity response of the blue-green algae Synechocystis sp. was measured through changes in growth rates. The inorganic pollutant silver nanoparticles (0.044 μM) were toxic. Gold nanoparticles did not affect the growth rate. The addition of 15 mg/L NOM partially inhibited …
Design And Analysis Of Cloaked Fluorophores For Rapid Detection And Visualization Of Cancer Cells Containing Nad(P)H:Quinone Oxidoreductase-1, William Silvers
Design And Analysis Of Cloaked Fluorophores For Rapid Detection And Visualization Of Cancer Cells Containing Nad(P)H:Quinone Oxidoreductase-1, William Silvers
LSU Doctoral Dissertations
The development of fluorogenic substrates for real-time tumor cell detection has led to a vastly expanding field for personal oncology. Fluorophores have been studied as appendages to larger scaffolds leading to accumulation of these dyes in tumor cells or their surrounding environment, taking advantage of tumor anatomy. A new class of fluorophores has been developed in which the dye is an active participant in the mechanism of cancer cell detection. These dyes have been conjugated such that their fluorescence has been eliminated or altered and will undergo a change to reveal their fluorescent signal upon activation by a mechanism that …
Studies Of A Dirhodium Tetraphosphine Catalyst For Hydroformylation And Aldehyde-Water Shift Catalysis, Aaron Rider Barnum
Studies Of A Dirhodium Tetraphosphine Catalyst For Hydroformylation And Aldehyde-Water Shift Catalysis, Aaron Rider Barnum
LSU Doctoral Dissertations
Research into the dirhodium tetraphosphine catalyst precursor [rac-Rh2(nbd)2(et,ph-P4)](BF4)2 shows it is capable of forming a highly active and regioselective hydroformylation catalyst in situ when using an acetone or acetone/water solvent. Hydroformylation experiments (using 1-hexene), FT-IR studies, and acid-base studies were performed to better understand the various complexes of the dirhodium catalyst cycle. These studies lead to the newly proposed catalyst mechanism when performed in an acetone/water solution, using the monocationic [rac-Rh2(H)(µ-CO)2(CO) (et,ph-P4)]+ as the proposed active catalyst complex for hydroformylation. For the conversion of 1-hexene to heptanal, it is capable of performing an initial rate of 30 turnovers per min, …
Geometrical And Electronic Structure Of Metal Oxide Nanoparticles On Silica And Alumina, Udaya Indike Rodrigo
Geometrical And Electronic Structure Of Metal Oxide Nanoparticles On Silica And Alumina, Udaya Indike Rodrigo
LSU Doctoral Dissertations
Recent studies demonstrated nanometer-scale combustion-generated nanoparticles cause demonstrable health effects. It is essential to understand the chemical characteristics of these nanoparticles. Since combustion-generated nanoparticles arise in complex mixtures, we employed a dendrimeric method to generate simpler, more reproducible nanoparticles, which were tethered to fumed silica and alumina to provide surrogates for fly ash. We collected XANES and EXAFS data, which are useful for characterizing disordered mixtures where the metal is a minor component. The effect of particle size on structural properties was studied with copper oxide nanoparticles on fumed silica. XANES data demonstrated copper atoms in the nanoparticles are present …
Fabrication, Analysis, Application, And Characterization Of Core-Containing Microparticles And Hydrophilic Microfluidic Devices Produced Via The Primary- And In Situ Tertiary-Amine Catalyzed Michael Addition Of Multifunctional Thiols To Multifunctional Acrylates, Christopher O. Bounds
LSU Doctoral Dissertations
The objective of this research was to investigate amine-catalyzed thiol-acrylate chemistry for various novel applications that could fully utilize the untapped potential of this useful and robust chemistry. The use of this chemistry in each application solved a problem, improved on a disadvantage of current technologies, and decreased the level of complexity in association with required time, cost, and/or preparation conditions. The first novel application conceived, applied, and analyzed was in the field of microencapsulation. A novel approach for the preparation of microparticles via a dispersion polymerization using the primary amine-catalyzed addition of a trithiol to a triacrylate was realized …
Chemical Crystallography At The Interface Of Physics, Chemistry, And In Engineering: Structure Determination Of Highly Correlated Extended Solids, Main Group Compounds, Coordination Complexes, And Bioceramics, Gregory Todd Mccandless
Chemical Crystallography At The Interface Of Physics, Chemistry, And In Engineering: Structure Determination Of Highly Correlated Extended Solids, Main Group Compounds, Coordination Complexes, And Bioceramics, Gregory Todd Mccandless
LSU Doctoral Dissertations
Multi-disciplinary research is essential to address the major challenges in science, engineering, and medicine. For these three areas, crystallography has played and continues to play a huge role by providing researchers with the means to determine the structure of a compound and relate these to its properties. This dissertation is highly interdisciplinary, focusing on structure determination of complex systems and materials with tailored applications. This work includes the characterization by single crystal and powder X-ray diffraction of intermetallic extended solids, layered metal oxides, inorganic complexes, discrete organic molecules, and bioceramics. These projects range from modeling translational disorder with pseudo-hexagonal symmetry …
Kinetic Studies On Lactonization Of Quinone Propionic Acid Derivatives For The Development Of Redox Responsive Liposomes, K. L. Iresha Sampathi Perera
Kinetic Studies On Lactonization Of Quinone Propionic Acid Derivatives For The Development Of Redox Responsive Liposomes, K. L. Iresha Sampathi Perera
LSU Master's Theses
ABSTRACT Stimuli-responsive liposome systems that utilize endogenous triggers of tumor microenvironment have generated great attention in recent drug delivery research. Among such formulations, redox-responsive liposomes seem highly promising for cancer treatment due to their potential to release high drug concentrations upon reduction (by reductase enzymes). The research described in this thesis involved the evaluation of kinetics of trimethyl-lock quinone propionic acid reduction and lactonization, which accounts for payload release from trimethyl-lock quinone propionic acid-decorated liposomes. To achieve the ultimate goal of this research, several trimethyl-lock quinone propionic acid-based amide compounds were synthesized and characterized. Kinetic studies were carried out with …
Studies On A Dirhodium Tetraphosphine Hydroformylation Catalyst, Darina Polakova
Studies On A Dirhodium Tetraphosphine Hydroformylation Catalyst, Darina Polakova
LSU Doctoral Dissertations
The dirhodium tetraphosphine catalyst [Rh2(nbd)2(rac-et,ph-P4)](BF4)2 was investigated in acetone and water/acetone in order to explain better hydroformylation results in the latter solvent. In-situ NMR spectroscopy showed slower degradation in water/acetone. Less tendency to form penta/hexacarbonyl complexes in water/acetone was shown by 31P{1H} NMR and FT-IR. A pH decrease and hydroformylation studies in presence of a base indicated formation of a monocationic monohydride species. A new reaction mechanism was suggested that takes into account the observed differences from the acetone solvent system. The presence of water enabled production of hydride species when the dirhodium catalyst was exposed to CO gas. We …
Synthesis Of Fluorescent Poly(Styrene Sulfonate), Wayne Alfred Huberty
Synthesis Of Fluorescent Poly(Styrene Sulfonate), Wayne Alfred Huberty
LSU Master's Theses
In 1978, Lee found an increase and then a large decrease in the diffusion coefficient of poly(lysine) as the concentration of salt is decreased (Lin, S. C.; Lee, W. I.; Schurr, J. M. Biopolymers 1978, 17, (4), 1041-1064). Since the “slow mode” discovery, many have studied it without finding a fully satisfactory answer. Additional dynamic light scattering (DLS) measurements have been the main experimental technique used for reinvestigating the slow mode decay. Although DLS is a powerful characterization tool, it depends on thermodynamic interactions. As complicated as they can be, thermodynamic interactions are much worse for polyelectrolytes because of the …
Investigations Into The Role Of Humic Acid In Biomembrane Permeability And The Effects Of Naturally Formed Gold And Silver Nanoparticles On These Interactions, Loice Marklyne Ojwang
Investigations Into The Role Of Humic Acid In Biomembrane Permeability And The Effects Of Naturally Formed Gold And Silver Nanoparticles On These Interactions, Loice Marklyne Ojwang
LSU Doctoral Dissertations
The mechanism and kinetics of the interaction of humic acids (HAs) with a 1-palmitoyl-2-oleoyl-Sn-glycero-3-phosphatidylcholine (POPC) large unilamellar vesicle (LUV) model biomembrane system were studied by fluorescence spectroscopy. All three HAs studied induced a perturbation to the biomembrane bilayer structure at pH 4.8. Concentration dependence studies revealed that biomembrane perturbation increased with increasing HA concentrations for Suwannee River HA (SWHA) from 0 to 20 mg C/L. For both Leonardite HA (LAHA) and Florida Peat HA (FPHA) aggregation influenced biomembrane perturbation at concentrations above 5 and 7.5 mg C/L, respectively. Temperature studies over the environmentally relevant ranges of 10 to 30 °C …
Ionic Materials For Applications In Sensing And Optoelectronics, Sergio L. De Rooy
Ionic Materials For Applications In Sensing And Optoelectronics, Sergio L. De Rooy
LSU Doctoral Dissertations
Organic salts consist of bulky anions and/or cations whose properties can be tailored for specific purposes. Ionic liquids (ILs) are (semi)organic salts with melting points below 100 ºC. They typically exhibit neglible vapor pressures, high thermal stability, wide liquidus range, and tunable solubility. Moreover specific functions can be built into their respective ions. The first part of the dissertation involves discussions of chiral ionic liquids with additional protic, magnetic, and magneto-luminescent properties, respectively. In addition to their enantioselective sensing capabilities, the ILs may find use in chiral separations and catalysis. The second part of the dissertation involves discussions of fluorescent …
Total Synthesis Of A Virotoxin And Analogs For Conformational Studies, Benson Jumba Edagwa
Total Synthesis Of A Virotoxin And Analogs For Conformational Studies, Benson Jumba Edagwa
LSU Doctoral Dissertations
This dissertation describes the first total synthesis of alloviroidin in trace amounts, along with that of three analogs containing L-proline (Pro), trans-3-hydroxyproline (3-Hyp) or cis-4-hydroxyproline (4-hyp) residue substituting for 2,3-trans-3,4-trans-dihydroxyproline in the natural product. We report herein an efficient strategy that provides a dipeptide containing a (2S,4S)-4,5-dihydroxyleucine (dihyLeu) residue, including a diastereoselective dihydroxylation. Nα-Carbobenzyloxy-(2S)-4,5-dehydroleucine was coupled with valine ethyl ester to give a dipeptide that was subjected to a Sharpless asymmetric dihydroxylation to introduce the diol. The relative configuration at C4 was assigned as S by X-ray crystallography after derivatization as an α-amino-γ-lactone hydrochloride salt. The preparation of the 2-(methylsulfonyl)tryptophan …
Chemical And Biological Evaluation Of Antibiotic-Based Ionic Liquids And Gumbos Against Pathogenic Bacteria, Marsha Rae Cole
Chemical And Biological Evaluation Of Antibiotic-Based Ionic Liquids And Gumbos Against Pathogenic Bacteria, Marsha Rae Cole
LSU Doctoral Dissertations
The research presented in this dissertation explores a novel pragmatic therapeutic approach for control, prevention, and treatment of infectious disease using Active-Pharmaceutical Ingredient-based Ionic Liquids (API-ILs) and Groups of Uniform Materials Based on Organic Salts (GUMBOS). Accordingly, several antiseptic- and antibiotic-based API-ILs and GUMBOS were synthesized and characterized using a combination of analytical and microbiological techniques. Overall, this research presents an advanced alternative to combination antibiotic therapy by using a novel group of ionic antimicrobial materials that have controlled pharmacokinetics, improved bioavailabilities, reduced toxicities, multi-modal properties, and potent antimicrobial spectrum of activity as a viable alternative to combating bacterial infections. …
Challenges In The Discovery And Characterization Of Magnetic Intermetallics, William A. Phelan
Challenges In The Discovery And Characterization Of Magnetic Intermetallics, William A. Phelan
LSU Doctoral Dissertations
The crystal growth and characterization of four families of compounds, LnFeSb3 (Ln = Pr, Nd, Sm, Gd, and Tb) and CeCo(Sb, Sn)3, Ln2Fe4Sb5 (Ln = La – Nd and Sm), LnCu2(Al,Si)5 (Ln = La and Ce), and Ln(Cu,Al,Ga)13 (Ln = La – Pr and Eu), are presented in this dissertation. Special emphasis is placed on describing their structure-magnetic properties correlations. Discoveries and studies of these systems were motivated by their structurally related predecessors, which are comprised of complex structural subunits and exhibit unusual physical properties. The magnetic behaviors exhibited by a selection of these intermetallics include the large magnetoresistances and …