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Georgia Southern University

Honors College Theses

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Full-Text Articles in Physical Sciences and Mathematics

A Nlp Approach To Automating The Generation Of Surveys For Market Research, Anav Chug May 2024

A Nlp Approach To Automating The Generation Of Surveys For Market Research, Anav Chug

Honors College Theses

Market Research is vital but includes activities that are often laborious and time consuming. Survey questionnaires are one possible output of the process and market researchers spend a lot of time manually developing questions for focus groups. The proposed research aims to develop a software prototype that utilizes Natural Language Processing (NLP) to automate the process of generating survey questions for market research. The software uses a pre-trained Open AI language model to generate multiple choice survey questions based on a given product prompt, send it to a targeted email list, and also provides a real-time analysis of the responses …

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Exploration Of Characteristic Curve In Fox Float 3 Shock Dampers To Expedite Shock Damp Tuning., Joshua R. Moore Apr 2024

Exploration Of Characteristic Curve In Fox Float 3 Shock Dampers To Expedite Shock Damp Tuning., Joshua R. Moore

Honors College Theses

The shock absorber is an integral part of a vehicle suspension system and has a strong influence on its performance, especially in the case of motorsports. It is important to study the force versus velocity relationship, commonly known as the characteristic curve of the shock absorber both during compression and rebound. Vendor-supplied characteristics often reflect the behavior of the shock absorber in a particular setting. However, during the installation, the settings inside the shock absorber are adjusted to increase the human comfort level and performance of the vehicle. This may change the characteristic curve of the shock. The available data …

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Using Pose Estimation Software To Predict Actions In Sabre Fencing, Micah Edwin Peters Ii Jan 2024

Using Pose Estimation Software To Predict Actions In Sabre Fencing, Micah Edwin Peters Ii

Honors College Theses

Fencing is a combat sport that uses three different swords: epee, foil, and sabre. Due to its fast-paced nature and employment of right of way, sabre fencing is often considered the most difficult of the three to learn. Computer vision and pose estimation software can be used to lower the barrier of entry to sabre fencing by identifying the different actions in sabre fencing. This project focuses on using open-source software to design a program that can identify the sabre parries as well as the main sabre movements. This program could be used to help newer fencers and spectators better …

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Amination Of 2-Bromo-6-Methylaminopyridine, Matthew H. Elterman Jan 2024

Amination Of 2-Bromo-6-Methylaminopyridine, Matthew H. Elterman

Honors College Theses

Extended metal atom chains (EMACs) represent molecular structures comprising a linear arrangement of metal ions, accompanied by supporting ligands. These compounds possess intriguing properties, yet remain understudied, drawing interest from diverse fields such as physics. However, synthesizing these multimetallic complexes poses significant challenges due to their intricate nature and specificity. Bridging ligands like silyl aminopyridine (SAP) and dipyridyl amine (DAP) have been utilized successfully to support EMACs, with SAP's application in this context being limited to a single published case, highlighting the urgent need for stabilization. This project aims to address this challenge through the synthesis of a novel scaffolded …

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Synthesis Of Chiral Amino Acids Via Direct Amination Of Diazo Ester With A Rhodium-Based Catalyst, Steven J. Boyles Jan 2024

Synthesis Of Chiral Amino Acids Via Direct Amination Of Diazo Ester With A Rhodium-Based Catalyst, Steven J. Boyles

Honors College Theses

Amino acids are critical molecules within living organisms as they are the building blocks of proteins. In organisms, proteins serve as regulators of necessary processes, structural components in tissue, hormones, and neurotransmitters. Amino acid therapy is an emerging treatment in the medical field used to treat symptoms of diseases such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. Amino acid therapies have also shown promising effects when it comes to treating mood disorders and weight management. In order to increase the number of amino acids available and increase the potential treatments for other ailments, there is a drive to increase …

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Counting Conjugates Of Colored Compositions, Jesus Omar Sistos Barron Jan 2024

Counting Conjugates Of Colored Compositions, Jesus Omar Sistos Barron

Honors College Theses

The properties of n-color compositions have been studied parallel to those of regular compositions. The conjugate of a composition as defined by MacMahon, however, does not translate well to n-color compositions, and there is currently no established analogous concept. We propose a conjugation rule for cyclic n-color compositions. We also count the number of self-conjugates under these rules and establish a couple of connections between these and regular compositions.

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Investigating The Relationship Between Inherited Geologic Framework And Saltwater Intrusion On St. Catherines Island, Georgia, Juliet Talaber, Jacque Kelly, Robert Vance Jan 2024

Investigating The Relationship Between Inherited Geologic Framework And Saltwater Intrusion On St. Catherines Island, Georgia, Juliet Talaber, Jacque Kelly, Robert Vance

Honors College Theses

Since the late 1800s, the oldest cities on the Georgia coast have been withdrawing water from the confined Floridan Aquifer System. As the population has grown, a cone of depression has formed extending from Savannah, GA to St. Catherines Island, GA, a barrier island 50 km southeast of Savannah. On St. Catherines Island, the cone of depression has reversed the lateral and horizontal groundwater flow gradients causing saltwater intrusion into the Upper Floridan Aquifer from the Lower Floridan Aquifer through joints, faults, or solution collapse features. Previous studies from the southern and central areas of the island have found evidence …

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Photodynamic Therapy Agents: The Power Of Mjöllnir To Eradicate Cancer, Sidney M. Hopper May 2023

Photodynamic Therapy Agents: The Power Of Mjöllnir To Eradicate Cancer, Sidney M. Hopper

Honors College Theses

After its discovery back in the 1900s, photosensitizers became a critical study for potential treatments and cures for medical issues, including cancer. It was discovered that porphyrins appeared to target and accumulate in proliferating cells, and to reach the cells, a certain wavelength of light with maximum absorbance associated with the porphyrin was necessary to achieve cell death. Photodynamic therapy involves making use of porphyrins or metalloporphyrins as activators when exposed to such light. When activated, these compounds generate reactive oxygen species (ROS), such as HO- or O2-, which can react with nucleic acids found in DNA and RNA. In …

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What Are The Impacts Of Deer Browsing And Japanese Stiltgrass (Microstegium Vinenium) On Native Sapling Growth In A Residential Wetland In Southeastern Georgia?, Josie Richards May 2023

What Are The Impacts Of Deer Browsing And Japanese Stiltgrass (Microstegium Vinenium) On Native Sapling Growth In A Residential Wetland In Southeastern Georgia?, Josie Richards

Honors College Theses

Wetlands promote biodiversity, act as climate stabilizers, and regulate water flow, yet are vulnerable to invaders. An invasive species can affect the biodiversity, abiotic conditions, and increase vulnerability of an ecosystem over time and deer browsing can actively affect new growth by removing the apical buds of young woody vegetation. Japanese stiltgrass (Microstegium vimineum), a wetland specific invader, has been shown to compete against native species for limited resources and actively crowd them out. Growth of native saplings can be further complicated by the presence of white tailed deer (Odocoileus virginianus), which browse woody vegetation and limit recruitment of trees. …

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Synthesis Of 2-Bromo-6-Alkylaminopyridines, 2,6-Dialkylaminopyridines, And Tren Based Ligands, Stephanie E. Carter Apr 2023

Synthesis Of 2-Bromo-6-Alkylaminopyridines, 2,6-Dialkylaminopyridines, And Tren Based Ligands, Stephanie E. Carter

Honors College Theses

Extended metal atom chains (EMAC) are multimetallic complexes that feature a linear metal chain with metal-metal bonds surrounded by stabilizing ligand molecules. When EMACs are formed with paramagnetic metal ions, unique magnetic properties can be derived from direct metal to metal communication. The challenge is that EMAC complexes are challenging to synthesize due to the inherent weakness of most M-M bonds and the specificity of the ligands required to stabilize EMACs. In prior work by the Guillet group, the silyl aminopyridine (SAP) ligands were observed to stabilize very unique triiron complexes, but they were inherently unstable. In other work, scaffolded …

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A Graphical User Interface Using Spatiotemporal Interpolation To Determine Fine Particulate Matter Values In The United States, Kelly M. Entrekin Apr 2023

A Graphical User Interface Using Spatiotemporal Interpolation To Determine Fine Particulate Matter Values In The United States, Kelly M. Entrekin

Honors College Theses

Fine particulate matter or PM2.5 can be described as a pollution particle that has a diameter of 2.5 micrometers or smaller. These pollution particle values are measured by monitoring sites installed across the United States throughout the year. While these values are helpful, a lot of areas are not accounted for as scientists are not able to measure all of the United States. Some of these unmeasured regions could be reaching high PM2.5 values over time without being aware of it. These high values can be dangerous by causing or worsening health conditions, such as cardiovascular and lung diseases. Within …

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Petrological And Geochemical Evaluation Of Rare-Earth Element Potential In The Sparta Granite Complex, Max J. Eshbaugh Jan 2023

Petrological And Geochemical Evaluation Of Rare-Earth Element Potential In The Sparta Granite Complex, Max J. Eshbaugh

Honors College Theses

Rare earth elements (REEs) are important resources with applications in the electronics, renewable energy, and automotive industries. REEs may be concentrated in the residual weathered portion of igneous parent rocks, typically granites. These residual deposits are mined in southeast Asia, but analogous climatic and geologic conditions suggest the existence of economically viable REE residual deposits in the southeastern United States (U.S.). The Sparta Granite Complex in east-central Georgia is a granitoid complex emplaced at the end of the Alleghanian orogeny, forming a suture between the Savannah River and Milledgeville terranes. Petrologic and geochemical assessments of the Sparta Granite and overlying …

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Synthesis, Characterization And Cell Viability Of Novel Tripodal Amines, Kinsley Lupton Nov 2022

Synthesis, Characterization And Cell Viability Of Novel Tripodal Amines, Kinsley Lupton

Honors College Theses

Cancer, over the years, has become a much more prevalent focus for the scientific community. Organizations and laboratories all over the world have spent countless hours searching for a cure, trying to learn more about what makes cancer so powerful and what is the best way to stop its growth. Iron-chelation drugs were already on the market, and it was shown that they did have the ability to act as both iron-chelators and anticancer drugs. Most of these iron-chelating drugs are not as effective at killing cancer cells as the medical field desires. Novel iron-chelating tris-indolyl derivatives, GSO2, GSO4 and …

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Circulation Transfer Between Adjacent Target Bose-Einstein Condensates, Charles B. Henry May 2022

Circulation Transfer Between Adjacent Target Bose-Einstein Condensates, Charles B. Henry

Honors College Theses

We propose an atomtronic rotation sensor design that consists of an array of Bose-Einstein Condensates (BECs) that are confined in a double-target-array potential. The rotation sensor's purpose is to measure the speed of the rotating frame, with respect to the “fixed stars", the sensor rests in. The atomtronic system is an ultracold gas of sodium atoms that have been compressed by laser light into a thin quasi-2D horizontal plane and further confined in the horizontal plane by a double-target-array potential. A target BEC is a combination of disk BEC that is surrounded by a ring BEC. A double-target BEC is …

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Type Of Synthetic Microfiber Influences Ingestion By Freshwater Worms, Sarah A. Martinez May 2022

Type Of Synthetic Microfiber Influences Ingestion By Freshwater Worms, Sarah A. Martinez

Honors College Theses

Plastics enter the environment from many sources, including clothing made from synthetic textiles, which shed a form of microplastics (microfibers) during their production, use and disposal. The impacts of microfibers on freshwater organisms are relatively unknown, therefore we tested the hypothesis that short- and long-term effects of microfibers on the aquatic worm, Lumbriculus variegatus, depend on the type of synthetic microfiber present. Microcosms containing L. variegatus, sediment and water were exposed to either no fibers (control) or one of three microfiber treatments (nylon, polyester or olefin) at the same concentration for 48 hours or 28 days. At the …

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Analysis Of The Light Responsive Azobenzene Peptide Nucleic Acid Duplexes, Kat Nguyen May 2022

Analysis Of The Light Responsive Azobenzene Peptide Nucleic Acid Duplexes, Kat Nguyen

Honors College Theses

Peptide nucleic acids (PNAs) are oligonucleotide analogues in which the sugar-phosphate backbone has been replaced by a pseudopeptide skeleton. Since PNAs use the natural nucleobases (Adenine, Thymine, Cytosine, Uracil, and Guanine) found in either DNA and/or RNA, they are able to hybridize according to Watson-Crick base-pairing to form duplexes. PNA is a promising therapeutic agent because they can function as antigene or antisense chemical agents. To further enhance their utility, we aim to incorporate a photoswitchable moiety using azobenzene. Here, we report the results of the synthesis and purification of a photoswitchable 11 mer PNA along with initial characterization efforts.

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Investigating Ionic Current Rectification As A Means Of Controllable Drug Delivery Using Silica Nanoparticles And Nano Porous Membranes, Katie L. Nolan Apr 2022

Investigating Ionic Current Rectification As A Means Of Controllable Drug Delivery Using Silica Nanoparticles And Nano Porous Membranes, Katie L. Nolan

Honors College Theses

This project investigates a novel ionic current rectification (ICR) phenomenon created by the opening and closing of nanopores by charged silica nanoparticles (SNPs) under electrophoretic flow. This voltage-controlled opening and closing of the pores can be exploited to allow delivery of nicotine through the pores at programmable intervals. The ICR phenomenon was thoroughly investigated by varying pH, buffer concentration, SNP concentration, and applied voltage range. The mechanism was also verified by testing with a 2-, 3-, and 5-electrode system. Potential cake layer formation was demonstrated in a longer ICR test, and the implications of this on the drug delivery mechanism …

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In The Face Of Climate Change, Does Human Trampling Affect Dune Resilience And Alter Ecosystem Services?, Alexandra O. Findlay Apr 2022

In The Face Of Climate Change, Does Human Trampling Affect Dune Resilience And Alter Ecosystem Services?, Alexandra O. Findlay

Honors College Theses

Sand dunes play a valuable role on the coastline supporting unique native species and protecting beach communities. The City of Tybee Island, Georgia, USA has undergone extensive dune restoration to expand and rehabilitate its shoreline to better defend the town against the increasing frequency of hurricanes and storm surge. The project included the recovery of existing dune structures and construction of new dunes filled with sand pumped from offshore and vegetated with a variety of native species. To analyze the impact of human trampling on dune vegetation occurring adjacent to footpaths and crossovers in new and established dunes, we measured …

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Effects Of Anharmonicity In A Dual-Sagnac Interferometer, Stephen Thomas Dec 2021

Effects Of Anharmonicity In A Dual-Sagnac Interferometer, Stephen Thomas

Honors College Theses

A recent experiment implemented a dual Sagnac atom interferometer (AI) for rotation sensing using a Bose-Einstein condensate (BEC) confined in a TOP-trap potential. The BEC is split twice by laser light to create two pairs of counter-orbiting clouds in a lowest-order harmonic potential with each pair acting as a separate Sagnac interferometer. After one orbit the two overlapping cloud pairs are split again and the interference patterns are inferred from the population of atoms in the zero-momentum state. We have simulated the impact of the presence of anharmonic terms in the potential on the performance of the AI as measured …

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A Deep Analysis And Algorithmic Approach To Solving Complex Fitness Issues In Collegiate Student Athletes, Holly N. Puckett Apr 2021

A Deep Analysis And Algorithmic Approach To Solving Complex Fitness Issues In Collegiate Student Athletes, Holly N. Puckett

Honors College Theses

Sports are not simply an entertainment source. For many, it creates a sense of community, support, and trust among both fans and athletes alike. In order to continue the sense of community sports provides, athletes must be properly cared for in order to perform at the highest level possible. Thus, their fitness and health must be monitored continuously. In a professional sense, one can expect individualized attention to athletes daily due to an abundance of funding and resources. However, when looking at college communities and student athletes within them, the number of athletes per athletic trainer increases due to both …

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Prediction Of Days-On-Market For Single-Family Homes In The Housing Market Of Savannah, Keagan Galbraith Apr 2021

Prediction Of Days-On-Market For Single-Family Homes In The Housing Market Of Savannah, Keagan Galbraith

Honors College Theses

The number of days that a home stays on the housing market (Days-On-Market—DOM) provides crucial information about the real estate market’s behavior that affects the buyer’s/seller’s decision (at the micro-level) and indicates the level of risk associated with real estate investments and identifies the housing bubbles (at the macro level). Housing data has a mixture of simple and complex attributes. A complex attribute in contrast with a simple attribute, has an array of values for a real estate property, which creates a major challenge in prediction of DOM. DOM is a binary attribute with values of “short” (£ six months) …

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Modeling The Stock Market Through Game Theory, Kylie Hannafey Apr 2021

Modeling The Stock Market Through Game Theory, Kylie Hannafey

Honors College Theses

Game Theory is used on many occasions to help us understand interactions between decision-makers. The famous Nash equilibrium is a steady state in a model that shows the interaction of different players, in which no player can do better by choosing a different action if the actions of the other players do not change. These two concepts can be applied to numerous situations that vary in types of players, but for our research, we are focusing on businesses in the stock market. The main objective is to use Game Theory to analyze data collected from the stock market, model our …

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Designing Efficient Algorithms For Sensor Placement, Gabriel Loos Mar 2021

Designing Efficient Algorithms For Sensor Placement, Gabriel Loos

Honors College Theses

Sensor placement has many applications and uses that can be seen everywhere you go.These include, but not limited to, monitoring the structural health of buildings and bridgesand navigating Unmanned Aerial Vehicles(UAV).We study ways that leads to efficient algorithms that will place as few as possible sen-sors to cover an entire area. We will tackle the problem from both 2-dimensional and3-dimensional points of view. Two famous related problems are discussed: the art galleryproblem and the terrain guarding problem. From the top view an area presents a 2-D im-age which will enable us to partition polygonal shapes and use graph theoretical results …

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Designing Peptides To Bind Kappa B Dna And Mimic Nf-Kappa B Protein Complexes, Nicholas A. Markowich May 2020

Designing Peptides To Bind Kappa B Dna And Mimic Nf-Kappa B Protein Complexes, Nicholas A. Markowich

Honors College Theses

Transcription factors are important proteins that regulate gene expression and protein synthesis. Transcription factors can either boost the gene’s transcription rate by helping RNA polymerase activate transcription or restrict it by interfering with RNA polymerase, thereby repressing transcription. Nuclear factor-kappa-B (NF-κB) transcription factors are a family of proteins that control the synthesis of proteins involved in many cellular processes such as inflammatory and immune responses, cell growth, and apoptosis. However, the overexpression and activation of these transcription factors is linked to deadly conditions such as cancer and neurodegenerative diseases which currently have few safe cures. The goal of this research …

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Silicon Quantum Dots Conjunctive With Stable Radicals: Potential Application In Non-Invasive Cancer Diagnostics, Daylan R. Post May 2020

Silicon Quantum Dots Conjunctive With Stable Radicals: Potential Application In Non-Invasive Cancer Diagnostics, Daylan R. Post

Honors College Theses

Quantum Dots, and nanomaterials in general, are one of the most promising areas of current physical study, especially their potential medical uses. In this study we introduced Nitroxide free radicals into a Silicon Quantum Dot (SiQD) solution and conducted experiments on the modified SiQDs in order to characterize their physical properties. We gathered emission, excitation, absorption and electron spin resonance (ESR) spectra of both modified and unmodified SiQDs. Previous studies have shown the possibility of using proteins as markers for cancer detection. Our measurements show the potential of using the interaction between these protein markers and SiQDs as a form …

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Symbolic Construction Of Matrix Functions In A Numerical Environment, Evan D. Butterworth Apr 2020

Symbolic Construction Of Matrix Functions In A Numerical Environment, Evan D. Butterworth

Honors College Theses

Within the field of Computational Science, the importance of programs and tools involving systems of differential equations cannot be overemphasized. Many industrial sites, such as nuclear power facilities, are unable to safely operate without these systems. This research explores and studies matrix differential equations and their applications to real computing structures. Through the use of software such as MatLab, I have constructed a toolbox, or collection, of programs that will allow any user to easily calculate a variety of matrix functions. The first tool in this collection is a program that computes the matrix exponential, famously studied and presented by …

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Structure Activity Relationship (Sar) Studies Of Neurotoxin Quinoline-Derivatives, Dylan Smeyne Apr 2020

Structure Activity Relationship (Sar) Studies Of Neurotoxin Quinoline-Derivatives, Dylan Smeyne

Honors College Theses

Structure activity relationship (SAR) studies are performed in order to identify the core structure that is responsible for the biological activity of an organic molecule. Recently, we have synthesized a drug prototype which contains several functional groups, such as an alcohol, an ester, a fluorine, and an aromatic ring. While studying in vivo toxicity of this molecule in zebrafish (Danio rerio) embryo, we observed that it has a unique biological activity that causes a sudden inactivity in embryo movement. Continued investigation revealed that this molecule blocks sodium channels in neurons causing a temporary anesthesia in Danio rerio embryo. The biological …

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Synthesized Tripodal Amine As Potential Anti-Cancer Therapeutic, Abigail G. Mcnamee Apr 2020

Synthesized Tripodal Amine As Potential Anti-Cancer Therapeutic, Abigail G. Mcnamee

Honors College Theses

Cancer remains a prevalent disease today. This disease may manifest itself in many different ways and affect a variety of tissues with everything from the brain to the blood. With this wide diversity of cancer types, treatment can be complicated since there is not a “one size fits all” treatment for the disease. Surgery, radiation, and chemotherapy are all options that must be weighed with their benefits and side effects. Ultimately though, there are not enough effective treatment options available for every type of cancer. This leaves many with the grim prognosis of never being cured. With this clear need …

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Electrolytic Oxidative Coupling Of Alcohols With Aldehydes To Form Esters, Katherine L. Verboom Jan 2020

Electrolytic Oxidative Coupling Of Alcohols With Aldehydes To Form Esters, Katherine L. Verboom

Honors College Theses

There are copious amounts of naturally occurring and synthetic esters known that have a wide range of applications in industry to produce fine chemicals. Traditional methods of ester synthesis involve a reaction between a carboxylic acid and an alcohol in the presence of a Bronsted acid catalyst. The primary objective of this research project was to carry out the ester synthesis using the electrochemical coupling of aldehydes with alcohols instead of with a Bronsted acid catalyst because the electrochemical coupling would be an all-around better alternative of ester synthesis than the traditional method of using the catalyst. Electrochemistry has long …

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Determination Of Optimal Mild Organic Solvents Of Pdnps For Carbon-Carbon Coupling Reactions, Trina Biswas Dec 2019

Determination Of Optimal Mild Organic Solvents Of Pdnps For Carbon-Carbon Coupling Reactions, Trina Biswas

Honors College Theses

The synthesis of nanoparticles is an increasingly popular field of interest. The application of nanoparticles is especially popular in the field of nanocatalysts. Metal nanoparticles (NPs) are favorable for catalysis because of the large surface area to volume ratio, which allows them to catalyze a variety of reactions using lesser amounts of active material. As the field of nanoparticle research expands, efforts are being made to create more sustainable approaches to the synthesis of these particles. This research sought to translate the benefits of peptide-based synthesis to organic solvents and use less toxic organic solvents for carbon-carbon coupling reactions, like …

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