Physical Sciences and Mathematics Commons^™

Detection Of Health-Related Behaviours Using Head-Mounted Devices, Shengjie Bi

Dartmouth College Ph.D Dissertations

The detection of health-related behaviors is the basis of many mobile-sensing applications for healthcare and can trigger other inquiries or interventions. Wearable sensors have been widely used for mobile sensing due to their ever-decreasing cost, ease of deployment, and ability to provide continuous monitoring. In this dissertation, we develop a generalizable approach to sensing eating-related behavior.

First, we developed Auracle, a wearable earpiece that can automatically detect eating episodes. Using an off-the-shelf contact microphone placed behind the ear, Auracle captures the sound of a person chewing as it passes through the head. This audio data is then processed by a …

A Multi-Resolution Graph Convolution Network For Contiguous Epitope Prediction, Lisa Oh

Dartmouth College Master’s Theses

Computational methods for predicting binding interfaces between antigens and antibodies (epitopes and paratopes) are faster and cheaper than traditional experimental structure determination methods. A sufficiently reliable computational predictor that could scale to large sets of available antibody sequence data could thus inform and expedite many biomedical pursuits, such as better understanding immune responses to vaccination and natural infection and developing better drugs and vaccines. However, current state-of-the-art predictors produce discontiguous predictions, e.g., predicting the epitope in many different spots on an antigen, even though in reality they typically comprise a single localized region. We seek to produce contiguous predicted epitopes, …