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Physical Sciences and Mathematics Commons

Open Access. Powered by Scholars. Published by Universities.®

City University of New York (CUNY)

2012

Dissertations and Theses

Chemistry

Articles 1 - 3 of 3

Full-Text Articles in Physical Sciences and Mathematics

Azide-Benzyne Cycloaddition And Olefination To Vinyl Benzotriazoles, Singh Govindra Jan 2012

Azide-Benzyne Cycloaddition And Olefination To Vinyl Benzotriazoles, Singh Govindra

Dissertations and Theses

No abstract provided.


Studies On Sucralose-Based Low Molecular Weight Gelators, Malick Samateh Jan 2012

Studies On Sucralose-Based Low Molecular Weight Gelators, Malick Samateh

Dissertations and Theses

Amphiphiles are molecules with both hydrophilic head and hydrophobic tail groups. Examples of amphiphiles include surfactants, detergents, soaps, bile acids/salts and lipids. Due to their amphiphilic nature, they tend to self-assemble in solution via non-covalent interactions such as hydrogen-bonding, π-π stacking and donor–acceptor interactions to form hierarchical morphologies like micelles, lamellae and fibers. The ones capable of subsequently forming gels are known as low molecular weight gelators (LMWGs). LMWGs usually form “polymer-like” fibers that interact to form a three-dimentional network known as a Self-Assembled Fibrillar Network (SAFIN), which entraps and immobilizes the entire solvent pool to form a viscoeslatic material …


Effects Of Arsenic And Uvb Radiation On Induction Of Cyclin D1 In Human Keratinocytes., Julian Gonzalez Jan 2012

Effects Of Arsenic And Uvb Radiation On Induction Of Cyclin D1 In Human Keratinocytes., Julian Gonzalez

Dissertations and Theses

Arsenic and Ultraviolet radiation B (UVB) are environmental toxins that have been linked to various epithelial cancers. Arsenic metabolism in humans leads to its collection in the skin, where it encounters and can act with known carcinogen UVB. Epidemiological evidence of the two toxins demonstrates their potential to affect signaling pathways, with various consequences. Here we employ an in vitro model system using Normal Human Epidermal Keratinocytes (NHEK) to identify the effect of arsenic and UVB on humans and whether they work synergistically. We find that although both cause induction of cyclin D1, culturing cells with both co-mutagens does not …