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Articles 1 - 30 of 53
Full-Text Articles in Physical Sciences and Mathematics
On The Impact Of Geospace Weather On The Occurrence Of M7.8/M7.5 Earthquakes On 6 February 2023 (Turkey), Possibly Associated With The Geomagnetic Storm Of 7 November 2022, Dimitar Ouzounov, Galina Khachikyan
On The Impact Of Geospace Weather On The Occurrence Of M7.8/M7.5 Earthquakes On 6 February 2023 (Turkey), Possibly Associated With The Geomagnetic Storm Of 7 November 2022, Dimitar Ouzounov, Galina Khachikyan
Mathematics, Physics, and Computer Science Faculty Articles and Research
A joint analysis of solar wind, geomagnetic field, and earthquake catalog data showed that before the catastrophic M = 7.8 and M = 7.5 Kahramanmaras earthquake sequence on 6 February 2023, a closed strong magnetic storm occurred on 7 November 2022, SYM/H = −117 nT. The storm started at 08:04 UT. At this time, the high-latitudinal part of Turkey’s longitudinal region of future epicenters was located under the polar cusp, where the solar wind plasma would directly access the Earth’s environment. The time delay between storm onset and earthquake occurrence was ~91 days. We analyzed all seven strong (M7+) earthquakes …
Detecting Drifts In Data Streams Using Kullback-Leibler (Kl) Divergence Measure For Data Engineering Applications, Jeomoan Francis Kurian, Mohamed Allali
Detecting Drifts In Data Streams Using Kullback-Leibler (Kl) Divergence Measure For Data Engineering Applications, Jeomoan Francis Kurian, Mohamed Allali
Engineering Faculty Articles and Research
The exponential growth of data coupled with the widespread application of artificial intelligence(AI) presents organizations with challenges in upholding data accuracy, especially within data engineering functions. While the Extraction, Transformation, and Loading process addresses error-free data ingestion, validating the content within data streams remains a challenge. Prompt detection and remediation of data issues are crucial, especially in automated analytical environments driven by AI. To address these issues, this study focuses on detecting drifts in data distributions and divergence within data fields processed from different sample populations. Using a hypothetical banking scenario, we illustrate the impact of data drift on automated …
Making The Most Of Artificial Intelligence And Large Language Models: A Novel Approach For Book Recommendation And Discovery In Medical Libraries, Ivan Portillo, David Carson
Making The Most Of Artificial Intelligence And Large Language Models: A Novel Approach For Book Recommendation And Discovery In Medical Libraries, Ivan Portillo, David Carson
Library Presentations, Posters, and Audiovisual Materials
This poster presentation evaluates the use of Artificial Intelligence and large language models (LLMs) to assist health science libraries in recommending and discovering book titles as part of their collection development. Using pre-determined prompts, the researchers evaluated ChatGPT 4.0, Bing Chat, and Google Bard as recommender systems for book discovery and ranking existing titles.
Toward Intuitive 3d Interactions In Virtual Reality: A Deep Learning- Based Dual-Hand Gesture Recognition Approach, Trudi Di Qi, Franceli L. Cibrian, Meghna Raswan, Tyler Kay, Hector M. Camarillo-Abad, Yuxin Wen
Toward Intuitive 3d Interactions In Virtual Reality: A Deep Learning- Based Dual-Hand Gesture Recognition Approach, Trudi Di Qi, Franceli L. Cibrian, Meghna Raswan, Tyler Kay, Hector M. Camarillo-Abad, Yuxin Wen
Engineering Faculty Articles and Research
Dual-hand gesture recognition is crucial for intuitive 3D interactions in virtual reality (VR), allowing the user to interact with virtual objects naturally through gestures using both handheld controllers. While deep learning and sensor-based technology have proven effective in recognizing single-hand gestures for 3D interactions, research on dual-hand gesture recognition for VR interactions is still underexplored. In this work, we introduce CWT-CNN-TCN, a novel deep learning model that combines a 2D Convolution Neural Network (CNN) with Continuous Wavelet Transformation (CWT) and a Temporal Convolution Network (TCN). This model can simultaneously extract features from the time-frequency domain and capture long-term dependencies using …
Canonical Extensions Of Quantale Enriched Categories, Alexander Kurz
Canonical Extensions Of Quantale Enriched Categories, Alexander Kurz
MPP Research Seminar
No abstract provided.
A Realist Interpretation Of Unitarity In Quantum Gravity, Indrajit Sen, Stephon Alexander, Justin Dressel
A Realist Interpretation Of Unitarity In Quantum Gravity, Indrajit Sen, Stephon Alexander, Justin Dressel
Mathematics, Physics, and Computer Science Faculty Articles and Research
Unitarity is a difficult concept to implement in canonical quantum gravity because of state non-normalisability and the problem of time. We take a realist approach based on pilot-wave theory to address this issue in the Ashtekar formulation of the Wheeler–DeWitt equation. We use the postulate of a definite configuration in the theory to define a global time for the gravitational-fermionic system recently discussed in Alexander et al (2022 Phys. Rev. D 106 106012), by parameterising a variation of a Weyl-spinor that depends on the Kodama state. The total Hamiltonian constraint yields a time-dependent Schrodinger equation, without semi-classical approximations, which we …
A Novel Correction For The Multivariate Ljung-Box Test, Minhao Huang
A Novel Correction For The Multivariate Ljung-Box Test, Minhao Huang
Computational and Data Sciences (PhD) Dissertations
This research introduces an analytical improvement to the Multivariate Ljung-Box test that addresses significant deviations of the original test from the nominal Type I error rates under almost all scenarios. Prior attempts to mitigate this issue have been directed at modification of the test statistics or correction of the test distribution to achieve precise results in finite samples. In previous studies, focused on designing corrections to the univariate Ljung-Box, a method that specifically adjusts the test rejection region has been the most successful of attaining the best Type I error rates. We adopt the same approach for the more complex, …
Computational Linguistics And Multilingualism: A Comparative Analysis With Spanish And English Data, Evelyn Lawrie
Computational Linguistics And Multilingualism: A Comparative Analysis With Spanish And English Data, Evelyn Lawrie
Student Scholar Symposium Abstracts and Posters
Computational linguistics is an increasingly ubiquitous field, serving as the basis for artificial intelligence and machine translation. It aims to analyze the syntax and semantics of individual words and phrases. While there have been in-depth advancements in computational linguistics strategies for the English language, others have not been developed as thoroughly. This lack of emphasis on multilingualism has contributed to the disappearance of Hispanic perspectives in the digital world. Especially those of indigenous heritage, as the decline of many indigenous languages has been exacerbated by the lack of digital translation services. Sentiment analysis is a branch of computational linguistics that …
Exploring Binding Pockets In The Conformational States Of The Sars-Cov-2 Spike Trimers For The Screening Of Allosteric Inhibitors Using Molecular Simulations And Ensemble-Based Ligand Docking, Grace Gupta, Gennady M. Verkhivker
Exploring Binding Pockets In The Conformational States Of The Sars-Cov-2 Spike Trimers For The Screening Of Allosteric Inhibitors Using Molecular Simulations And Ensemble-Based Ligand Docking, Grace Gupta, Gennady M. Verkhivker
Mathematics, Physics, and Computer Science Faculty Articles and Research
Understanding mechanisms of allosteric regulation remains elusive for the SARS-CoV-2 spike protein, despite the increasing interest and effort in discovering allosteric inhibitors of the viral activity and interactions with the host receptor ACE2. The challenges of discovering allosteric modulators of the SARS-CoV-2 spike proteins are associated with the diversity of cryptic allosteric sites and complex molecular mechanisms that can be employed by allosteric ligands, including the alteration of the conformational equilibrium of spike protein and preferential stabilization of specific functional states. In the current study, we combine conformational dynamics analysis of distinct forms of the full-length spike protein trimers and …
Synthesis Of Thermoresponsive Poly(N-Isopropyl Acrylamide) Based Core-Shell And Hollow Shell Nanogel With Tunable Core And Shell Thickness, Mohamad Hijazi, Molla R. Islam
Synthesis Of Thermoresponsive Poly(N-Isopropyl Acrylamide) Based Core-Shell And Hollow Shell Nanogel With Tunable Core And Shell Thickness, Mohamad Hijazi, Molla R. Islam
Student Scholar Symposium Abstracts and Posters
Nanogels have emerged as a notably safer and more effective means for drug delivery, primarily due to their adjustable drug-loading capabilities. Hollow-core nanoparticles offer some unique properties that are desirable for drug delivery applications. Initially, silica core nanoparticles were synthesized using the Stöber process at different temperatures where Tetraethoxysilane (TEOS) undergoes hydrolysis in the presence of ethanol and then a condensation reaction to form silica nanoparticles. Scanning Electron Microscopy (SEM) and Optical Microscopy (OM) analysis revealed that the size of silica core particles varied with the synthesis temperature (300 nm at 30°C to 150 at 60°C). The core silica particles …
Dancetag: Using Sensors To Improve Feedback Given To Dance Students, Yanelly Mego
Dancetag: Using Sensors To Improve Feedback Given To Dance Students, Yanelly Mego
Student Scholar Symposium Abstracts and Posters
The structure of dance classrooms has remained unchanged for several years. Very little, if any, technology has been incorporated to improve the quality of teaching. This has motivated our research project, whose goal is to capture dance movements with wearable sensors, to develop DANCETAG (Data Analytics and Notation with Captured Event Tagging). This is a platform that allows the gathering of data captured by Sony’s Mocopi sensors and annotating them with the dancer's movements. The Mocopi sensors make up a motion capture system. It is comprised of six small, round sensors that can be attached to velcro straps and clips. …
Philosophy In Science: Can Philosophers Of Science Permeate Through Science And Produce Scientific Knowledge?, Thomas Pradeu, Maël Lemoine, Mahdi Khelfaoui, Yves Gingras
Philosophy In Science: Can Philosophers Of Science Permeate Through Science And Produce Scientific Knowledge?, Thomas Pradeu, Maël Lemoine, Mahdi Khelfaoui, Yves Gingras
Presidential Fellows Articles and Research
Most philosophers of science do philosophy ‘on’ science. By contrast, others do philosophy ‘in’ science (PinS), that is, they use philosophical tools to address scientific problems and to provide scientifically useful proposals. Here, we consider the evidence in favour of a trend of this nature. We proceed in two stages. First, we identify relevant authors and articles empirically with bibliometric tools, given that PinS would be likely to infiltrate science and thus to be published in scientific journals (‘intervention’), cited in scientific journals (‘visibility’), and sometimes recognized as a scientific result by scientists (‘contribution’). We show that many central figures …
Predicting Ffar4 Agonists Using Structure-Based Machine Learning Approach Based On Molecular Fingerprints, Zaid Anis Sherwani, Syeda Sumayya Tariq, Mamona Mushtaq, Ali Raza Siddiqui, Mohammad Nur-E-Alam, Aftab Ahmed, Zaheer Ul-Haq
Predicting Ffar4 Agonists Using Structure-Based Machine Learning Approach Based On Molecular Fingerprints, Zaid Anis Sherwani, Syeda Sumayya Tariq, Mamona Mushtaq, Ali Raza Siddiqui, Mohammad Nur-E-Alam, Aftab Ahmed, Zaheer Ul-Haq
Pharmacy Faculty Articles and Research
Free Fatty Acid Receptor 4 (FFAR4), a G-protein-coupled receptor, is responsible for triggering intracellular signaling pathways that regulate various physiological processes. FFAR4 agonists are associated with enhancing insulin release and mitigating the atherogenic, obesogenic, pro-carcinogenic, and pro-diabetogenic effects, normally associated with the free fatty acids bound to FFAR4. In this research, molecular structure-based machine-learning techniques were employed to evaluate compounds as potential agonists for FFAR4. Molecular structures were encoded into bit arrays, serving as molecular fingerprints, which were subsequently analyzed using the Bayesian network algorithm to identify patterns for screening the data. The shortlisted hits obtained via machine learning protocols …
Kinematic And Dynamic Structure Of The 18 May 2020 Squall Line Over South Korea, Wishnu Agum Swastiko, Chia-Lun Tsai, Seung Hee Kim, Gyuwon Lee
Kinematic And Dynamic Structure Of The 18 May 2020 Squall Line Over South Korea, Wishnu Agum Swastiko, Chia-Lun Tsai, Seung Hee Kim, Gyuwon Lee
Institute for ECHO Articles and Research
The diagonal squall line that passed through the Korean Peninsula on the 18 May 2020 was examined using wind data retrieved from multiple Doppler radar synthesis focusing on its kinematic and dynamic aspects. The low-level jet, along with warm and moist air in the lower level, served as the primary source of moisture supply during the initiation and formation process. The presence of a cold pool accompanying the squall line played a role in retaining moisture at the surface. As the squall line approached the Korean Peninsula, the convective bands in the northern segment (NS) and southern segment (SS) of …
Gate-Controlled Supercurrent Effect In Dry-Etched Dayem Bridges Of Non-Centrosymmetric Niobium Rhenium, Jennifer Koch, Carla Cirillo, Sebastiano Battisti, Leon Ruf, Zahra Makhdoumi Kakhaki, Alessandro Paghi, Armen Gulian, Serafim Teknowijoyo, Giorgio De Simoni, Francesco Giazotto, Carmine Attanasio, Elke Scheer, Angelo Di Bernardo
Gate-Controlled Supercurrent Effect In Dry-Etched Dayem Bridges Of Non-Centrosymmetric Niobium Rhenium, Jennifer Koch, Carla Cirillo, Sebastiano Battisti, Leon Ruf, Zahra Makhdoumi Kakhaki, Alessandro Paghi, Armen Gulian, Serafim Teknowijoyo, Giorgio De Simoni, Francesco Giazotto, Carmine Attanasio, Elke Scheer, Angelo Di Bernardo
Mathematics, Physics, and Computer Science Faculty Articles and Research
The application of a gate voltage to control the superconducting current flowing through a nanoscale superconducting constriction, named as gate-controlled supercurrent (GCS), has raised great interest for fundamental and technological reasons. To gain a deeper understanding of this effect and develop superconducting technologies based on it, the material and physical parameters crucial for the GCS effect must be identified. Top-down fabrication protocols should also be optimized to increase device scalability, although studies suggest that top-down fabricated devices are more resilient to show a GCS. Here, we investigate gated superconducting nanobridges made with a top-down fabrication process from thin films of …
Generalized Q-Fock Spaces And Structural Identities, Daniel Alpay, Paula Cerejeiras, Uwe Kaehler, Baruch Schneider
Generalized Q-Fock Spaces And Structural Identities, Daniel Alpay, Paula Cerejeiras, Uwe Kaehler, Baruch Schneider
Mathematics, Physics, and Computer Science Faculty Articles and Research
Using 𝑞-calculus we study a family of reproducing kernel Hilbert spaces which interpolate between the Hardy space and the Fock space. We give characterizations of these spaces in terms of classical operators such as integration and backward-shift operators, and their 𝑞-calculus counterparts. Furthermore, these new spaces allow us to study intertwining operators between classic backward-shift operators and the q-Jackson derivative.
On Axially Rational Regular Functions And Schur Analysis In The Clifford-Appell Setting, Daniel Alpay, Fabrizio Colombo, Antonino De Martino, Kamal Diki, Irene Sabadini
On Axially Rational Regular Functions And Schur Analysis In The Clifford-Appell Setting, Daniel Alpay, Fabrizio Colombo, Antonino De Martino, Kamal Diki, Irene Sabadini
Mathematics, Physics, and Computer Science Faculty Articles and Research
In this paper we start the study of Schur analysis for Cauchy–Fueter regular quaternionic-valued functions, i.e. null solutions of the Cauchy–Fueter operator in . The novelty of the approach developed in this paper is that we consider axially regular functions, i.e. functions spanned by the so-called Clifford-Appell polynomials. This type of functions arises naturally from two well-known extension results in hypercomplex analysis: the Fueter mapping theorem and the generalized Cauchy–Kovalevskaya (GCK) extension. These results allow one to obtain axially regular functions starting from analytic functions of one real or complex variable. Precisely, in the Fueter theorem two operators play a …
Ultrasoft Platelet-Like Particles Stop Bleeding In Rodent And Porcine Models Of Trauma, Kimberly Nellenbach, Emily Mihalko, Seema Nandi, Drew W. Koch, Jagathpala Shetty, Leandra Moretti, Jennifer Sollinger, Nina Moiseiwitsch, Ana Sheridan, Sanika Pandit, Maureane Hoffman, Lauren V. Schnabel, L. Andrew Lyon, Thomas H. Barker, Ashley C. Brown
Ultrasoft Platelet-Like Particles Stop Bleeding In Rodent And Porcine Models Of Trauma, Kimberly Nellenbach, Emily Mihalko, Seema Nandi, Drew W. Koch, Jagathpala Shetty, Leandra Moretti, Jennifer Sollinger, Nina Moiseiwitsch, Ana Sheridan, Sanika Pandit, Maureane Hoffman, Lauren V. Schnabel, L. Andrew Lyon, Thomas H. Barker, Ashley C. Brown
Engineering Faculty Articles and Research
Uncontrolled bleeding after trauma represents a substantial clinical problem. The current standard of care to treat bleeding after trauma is transfusion of blood products including platelets; however, donated platelets have a short shelf life, are in limited supply, and carry immunogenicity and contamination risks. Consequently, there is a critical need to develop hemostatic platelet alternatives. To this end, we developed synthetic platelet-like particles (PLPs), formulated by functionalizing highly deformable microgel particles composed of ultralow cross-linked poly (N-isopropylacrylamide) with fibrin-binding ligands. The fibrin-binding ligand was designed to target to wound sites, and the cross-linking of fibrin polymers was designed …
Apigenin Alleviates Autistic-Like Stereotyped Repetitive Behaviors And Mitigates Brain Oxidative Stress In Mice, Petrilla Jayaprakash, Dmytro Isaev, Keun-Hang Susan Yang, Rami Beiram, Murat Oz, Bassem Sadek
Apigenin Alleviates Autistic-Like Stereotyped Repetitive Behaviors And Mitigates Brain Oxidative Stress In Mice, Petrilla Jayaprakash, Dmytro Isaev, Keun-Hang Susan Yang, Rami Beiram, Murat Oz, Bassem Sadek
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
Studying the involvement of nicotinic acetylcholine receptors (nAChRs), specifically α7-nAChRs, in neuropsychiatric brain disorders such as autism spectrum disorder (ASD) has gained a growing interest. The flavonoid apigenin (APG) has been confirmed in its pharmacological action as a positive allosteric modulator of α7-nAChRs. However, there is no research describing the pharmacological potential of APG in ASD. The aim of this study was to evaluate the effects of the subchronic systemic treatment of APG (10–30 mg/kg) on ASD-like repetitive and compulsive-like behaviors and oxidative stress status in the hippocampus and cerebellum in BTBR mice, utilizing the reference drug aripiprazole (ARP, 1 …
Cardiogpt: An Ecg Interpretation Generation Model, Guohua Fu, Jianwei Zheng, Islam Abudayyeh, Chizobam Ani, Cyril Rakovski, Louis Ehwerhemuepha, Hongxia Lu, Yongjuan Guo, Shenglin Liu, Huimin Chu, Bing Yang
Cardiogpt: An Ecg Interpretation Generation Model, Guohua Fu, Jianwei Zheng, Islam Abudayyeh, Chizobam Ani, Cyril Rakovski, Louis Ehwerhemuepha, Hongxia Lu, Yongjuan Guo, Shenglin Liu, Huimin Chu, Bing Yang
Mathematics, Physics, and Computer Science Faculty Articles and Research
Numerous supervised learning models aimed at classifying 12-lead electrocardiograms into different groups have shown impressive performance by utilizing deep learning algorithms. However, few studies are dedicated to applying the Generative Pre-trained Transformer (GPT) model in interpreting electrocardiogram (ECG) using natural language. Thus, we are pioneering the exploration of this uncharted territory by employing the CardioGPT model to tackle this challenge. We used a dataset of ECGs (standard 10s, 12-channel format) from adult patients, with 60 distinct rhythms or conduction abnormalities annotated by board-certified, actively practicing cardiologists. The ECGs were collected from The First Affiliated Hospital of Ningbo University and Shanghai …
Nowcasting Heavy Rainfall With Convolutional Long Short-Term Memory Networks: A Pixelwise Modeling Approach, Yi Victor Wang, Seung Hee Kim, Geunsu Lyu, Choeng-Lyong Lee, Soorok Ryu, Gyuwon Lee, Ki-Hong Min, Menas C. Kafatos
Nowcasting Heavy Rainfall With Convolutional Long Short-Term Memory Networks: A Pixelwise Modeling Approach, Yi Victor Wang, Seung Hee Kim, Geunsu Lyu, Choeng-Lyong Lee, Soorok Ryu, Gyuwon Lee, Ki-Hong Min, Menas C. Kafatos
Institute for ECHO Articles and Research
The recent decades have seen an increasing academic interest in leveraging machine learning approaches to nowcast, or forecast in a highly short-term manner, precipitation at a high resolution, given the limitations of the traditional numerical weather prediction models on this task. To capture the spatiotemporal associations of data on input variables, a deep learning (DL) architecture with the combination of a convolutional neural network and a recurrent neural network can be an ideal design for nowcasting rainfall. In this study, a long short-term memory (LSTM) modeling structure is proposed with convolutional operations on input variables. To resolve the issue of …
Accurate Characterization Of Binding Kinetics And Allosteric Mechanisms For The Hsp90 Chaperone Inhibitors Using Ai-Augmented Integrative Biophysical Studies, Chao Xu, Xianglei Zhang, Lianghao Zhao, Gennady M. Verkhivker, Fang Bai
Accurate Characterization Of Binding Kinetics And Allosteric Mechanisms For The Hsp90 Chaperone Inhibitors Using Ai-Augmented Integrative Biophysical Studies, Chao Xu, Xianglei Zhang, Lianghao Zhao, Gennady M. Verkhivker, Fang Bai
Mathematics, Physics, and Computer Science Faculty Articles and Research
The binding kinetics of drugs to their targets are gradually being recognized as a crucial indicator of the efficacy of drugs in vivo, leading to the development of various computational methods for predicting the binding kinetics in recent years. However, compared with the prediction of binding affinity, the underlying structure and dynamic determinants of binding kinetics are more complicated. Efficient and accurate methods for predicting binding kinetics are still lacking. In this study, quantitative structure–kinetics relationship (QSKR) models were developed using 132 inhibitors targeting the ATP binding domain of heat shock protein 90α (HSP90α) to predict the dissociation rate …
Bibliography For "Earth Day Display: Planet Vs Plastics: A Book Display Increasing The Awareness Of The Harms Of Plastic In Our Ecosystem", Arianna Tillman, Isabella Piechota, Kalea Brown
Bibliography For "Earth Day Display: Planet Vs Plastics: A Book Display Increasing The Awareness Of The Harms Of Plastic In Our Ecosystem", Arianna Tillman, Isabella Piechota, Kalea Brown
Library Displays and Bibliographies
A bibliography created to accompany a display about Earth Day, sustainability, and the harms of plastic during April 2024 at the Leatherby Libraries at Chapman University.
Climate Change-Associated Declines In Water Clarity Impair Feeding By Common Loons, Walter H. Piper, Max R. Glines, Kevin C. Rose
Climate Change-Associated Declines In Water Clarity Impair Feeding By Common Loons, Walter H. Piper, Max R. Glines, Kevin C. Rose
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
Climate change has myriad impacts on ecosystems, but the mechanisms by which it affects individual species can be difficult to pinpoint. One strategy to discover such mechanisms is to identify a specific ecological factor related to survival or reproduction and determine how that factor is affected by climate. Here we used Landsat imagery to calculate water clarity for 127 lakes in northern Wisconsin from 1995 to 2021 and thus investigate the effect of clarity on the body condition of an aquatic visual predator, the common loon (Gavia immer). In addition, we examined rainfall and temperature as potential predictors …
Enhancing Landslide Susceptibility Modelling Through A Novel Non-Landslide Sampling Method And Ensemble Learning Technique, Chao Zhou, Yue Wang, Ying Cao, Ramesh P. Singh, Bayes Ahmed, Mahdi Motagh, Yang Wang, Ling Chen, Guangchao Tan, Shanshan Li
Enhancing Landslide Susceptibility Modelling Through A Novel Non-Landslide Sampling Method And Ensemble Learning Technique, Chao Zhou, Yue Wang, Ying Cao, Ramesh P. Singh, Bayes Ahmed, Mahdi Motagh, Yang Wang, Ling Chen, Guangchao Tan, Shanshan Li
Mathematics, Physics, and Computer Science Faculty Articles and Research
In recent years, several catastrophic landslide events have been observed throughout the globe, threatening to lives and infrastructures. To minimize the impact of landslides, the need of landslide susceptibility map is important. The study aims to extract high-quality non-landslide samples and improve the accuracy of landslide susceptibility modelling (LSM) outcomes by applying a coupled method of ensemble learning and Machine Learning (ML). The Zigui-Badong section of the Three Gorges Reservoir area (TGRA) in China was considered in the present study. Twelve influencing factors were selected as inputs for LSM, and the relationship between each causal factor and landslide spatial development …
Methionyl-Trna Synthetase Synthetic And Proofreading Activities Are Determinants Of Antibiotic Persistence, Whitney N. Wood, Miguel Angel Rubio, Lorenzo Eugenio Leiva, Gregory J. Phillips, Michael Ibba
Methionyl-Trna Synthetase Synthetic And Proofreading Activities Are Determinants Of Antibiotic Persistence, Whitney N. Wood, Miguel Angel Rubio, Lorenzo Eugenio Leiva, Gregory J. Phillips, Michael Ibba
Biology, Chemistry, and Environmental Sciences Faculty Articles and Research
Bacterial antibiotic persistence is a phenomenon where bacteria are exposed to an antibiotic and the majority of the population dies while a small subset enters a low metabolic, persistent, state and are able to survive. Once the antibiotic is removed the persistent population can resuscitate and continue growing. Several different molecular mechanisms and pathways have been implicated in this phenomenon. A common mechanism that may underly bacterial antibiotic persistence is perturbations in protein synthesis. To investigate this mechanism, we characterized four distinct metG mutants for their ability to increase antibiotic persistence. Two metG mutants encode changes near the catalytic site …
Toward Local Madelung Mechanics In Spacetime, Mordecai Waegell
Toward Local Madelung Mechanics In Spacetime, Mordecai Waegell
Mathematics, Physics, and Computer Science Faculty Articles and Research
It has recently been shown that relativistic quantum theory leads to a local interpretation of quantum mechanics wherein the universal wavefunction in configuration space is entirely replaced with an ensemble of local fluid equations in spacetime. For want of a fully relativistic quantum fluid treatment, we develop a model using the nonrelativistic Madelung equations, and obtain conditions for them to be local in spacetime. Every particle in the Madelung fluid is equally real, and has a definite position, momentum, kinetic energy, and potential energy. These are obtained by defining quantum momentum and kinetic energy densities for the fluid and separating …
Alternative Robust Ways Of Witnessing Nonclassicality In The Simplest Scenario, Massy Khoshbin, Lorenzo Catani, Matthew Leifer
Alternative Robust Ways Of Witnessing Nonclassicality In The Simplest Scenario, Massy Khoshbin, Lorenzo Catani, Matthew Leifer
Mathematics, Physics, and Computer Science Faculty Articles and Research
In this paper we relate notions of nonclassicality in what is known as the simplest nontrivial scenario (a prepare and measure scenario composed of four preparations and two binary-outcome tomographically complete measurements). Specifically, we relate the established method developed by Pusey [M. F. Pusey, Phys. Rev. A 98, 022112 (2018)] to witness a violation of preparation noncontextuality, that is not suitable in experiments where the operational equivalences to be tested are specified in advance, with an approach based on the notion of bounded ontological distinctness for preparations, defined by Chaturvedi and Saha [A. Chaturvedi and D. Saha, Quantum …
Β-Sheets Mediate The Conformational Change And Allosteric Signal Transmission Between The Aslov2 Termini, Sian Xiao, Mayar Terek Ibrahim, Gennady M. Verkhivker, Brian D. Zoltowski, Peng Tao
Β-Sheets Mediate The Conformational Change And Allosteric Signal Transmission Between The Aslov2 Termini, Sian Xiao, Mayar Terek Ibrahim, Gennady M. Verkhivker, Brian D. Zoltowski, Peng Tao
Mathematics, Physics, and Computer Science Faculty Articles and Research
Avena sativa phototropin 1 light-oxygen-voltage 2 domain (AsLOV2) is a model protein of Per-Arnt-Sim (PAS) superfamily, characterized by conformational changes in response to external environmental stimuli. This conformational change begins with the unfolding of the N-terminal A'α helix in the dark state followed by the unfolding of the C-terminal Jα helix. The light state is characterized by the unfolded termini and the subsequent modifications in hydrogen bond patterns. In this photoreceptor, β-sheets are identified as crucial components for mediating allosteric signal transmission between the two termini. Through combined experimental and computational investigations, the Hβ …
Ground Electric Field, Atmospheric Weather And Electric Grid Variations In Northeast Greece Influenced By The March 2012 Solar Activity And The Moderate To Intense Geomagnetic Storms, Georgios Anagnostopoulos, Anastasios Karkanis, Athanasios Kampatagis, Panagiotis Marhavilas, Sofia-Anna Menesidou, Dimitrios Efthymiadis, Stefanos Keskinis, Dimitar Ouzounov, Nick Hatzigeorgiu, Michael Danakis
Ground Electric Field, Atmospheric Weather And Electric Grid Variations In Northeast Greece Influenced By The March 2012 Solar Activity And The Moderate To Intense Geomagnetic Storms, Georgios Anagnostopoulos, Anastasios Karkanis, Athanasios Kampatagis, Panagiotis Marhavilas, Sofia-Anna Menesidou, Dimitrios Efthymiadis, Stefanos Keskinis, Dimitar Ouzounov, Nick Hatzigeorgiu, Michael Danakis
Mathematics, Physics, and Computer Science Faculty Articles and Research
In a recent paper, we extended a previous study on the solar solar influence to the generation of the March 2012 heatwave in the northeastern USA. In the present study we check the possible relationship of solar activity with the early March 2012 bad weather in northeast Thrace, Greece. To this end, we examined data from various remote sensing instrumentation monitoring the Sun (SDO satellite), Interplanetary space (ACE satellite), the Earth’s magnetosphere (Earth-based measurements, NOAA-19 satellite), the top of the clouds (Terra and Aqua satellites), and the near ground atmosphere. Our comparative data analysis suggests that: (i) the winter-like weather …