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Chapman University

2021

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Articles 1 - 30 of 101

Full-Text Articles in Physical Sciences and Mathematics

Dynamic Relationship Study Between The Observed Seismicity And Spatiotemporal Pattern Of Lineament Changes In Palghar, North Maharashtra (India), Biswajit Nath, Ramesh P. Singh, Vineet K. Gahalaut, Ajay P. Singh Dec 2021

Dynamic Relationship Study Between The Observed Seismicity And Spatiotemporal Pattern Of Lineament Changes In Palghar, North Maharashtra (India), Biswajit Nath, Ramesh P. Singh, Vineet K. Gahalaut, Ajay P. Singh

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The Palghar region (north Maharashtra, India), located in the northwestern part of the stable continental region of India, experienced a low magnitude earthquake swarm, which was initiated in September 2018 and is continuing to date (as of October 2021). From December 2018 to December 2020, ~5000 earthquakes with magnitudes from M1.2 to M3.8 occurred in a small region of 20 × 10 km2. These earthquakes were probably triggered by fluid migration during seasonal rainfall. In this study, we have used multi-temporal Landsat satellite data of the year 2000, 2015, 2018, 2019, and 2020, extracted lineaments, and studied the …

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Progressive Destabilization And Triggering Mechanism Analysis Using Multiple Data For Chamoli Rockslide Of 7 February 2021, Wenfei Mao, Lixin Wu, Ramesh P. Singh, Yuan Qi, Busheng Xie, Yingjia Liu, Yifan Ding, Zilong Zhou, Jia Li Dec 2021

Progressive Destabilization And Triggering Mechanism Analysis Using Multiple Data For Chamoli Rockslide Of 7 February 2021, Wenfei Mao, Lixin Wu, Ramesh P. Singh, Yuan Qi, Busheng Xie, Yingjia Liu, Yifan Ding, Zilong Zhou, Jia Li

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

A catastrophic rockslide occurred on 7 February 2021 in Chamoli area in the high Himalaya. In the absence of field data, multiple satellites data of decade span have been used to investigate and understand the progressive destabilization of rockslide body. A 3D geometric model was developed using geospatial information about geology, terrain, and ice cover to understand the triggering mechanism. Several causes are uncovered as: the pronounced long-term change of land surface temperature facilitated local permafrost degradation and led to ice cover shrinking since 2010; the occurrence of ice avalanche nearby in 2016 accompanying with sidewall-to-bedrock fracturing enhanced the ice …

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Violation Of Magnetic Flux Conservation By Superconducting Nanorings, Iris Mowgood, Gurgen Melkonyan, Rajendra Dulal, Serafim Teknowijoyo, Sara Chahid, Armen Gulian Dec 2021

Violation Of Magnetic Flux Conservation By Superconducting Nanorings, Iris Mowgood, Gurgen Melkonyan, Rajendra Dulal, Serafim Teknowijoyo, Sara Chahid, Armen Gulian

Mathematics, Physics, and Computer Science Faculty Articles and Research

The behavior of magnetic flux in the ring-shaped finite-gap superconductors is explored from the view-point of the flux-conservation theorem which states that under the variation of external magnetic field "the magnetic flux through the ring remains constant" (see, e.g., [L.D. Landau and E.M. Lifshitz, Electrodynamics of Continuos Media, vol. 8 (New York, Pergamon Press, 1960), Section 42]). Our results, based on the time-dependent Ginzburg-Landau equations and COMSOL modeling, made it clear that in the general case, this theorem is incorrect. While for rings of macroscopic sizes the corrections are small, for micro and nanorings they become rather substantial. The physical …

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An Information-Theoretic Analysis Of Adherence To Physical Exercise Routines, Lily Foster Dec 2021

An Information-Theoretic Analysis Of Adherence To Physical Exercise Routines, Lily Foster

Computational and Data Sciences (MS) Theses

One of the most common recommendations in healthcare is to simply form healthy habits, but little research has been done to understand the formation and continuation of a healthy habit that isn’t heavily influenced by an individual’s interpretation. Arizona State University’s WalkIT study aimed to analyze how goal setting and financial reinforcement can influence moderate-to-vigorous physical activity (MVPA) in adults, while using data from accelerometers to alleviate individual bias. In this trial, 512 insufficiently active adults were recruited to wear an accelerometer for 1 year and were then randomly assigned to one of the four study groups. Each group had …

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Fabricating Nanophotonic Devices Using Nanofabrication Techniques, Scott Cummings Dec 2021

Fabricating Nanophotonic Devices Using Nanofabrication Techniques, Scott Cummings

Student Scholar Symposium Abstracts and Posters

Nanofabrication processes are widely used to make the integrated circuits and computer chips that are ubiquitous in today’s technology. These fabrication processes can also be applied to the creation of nanophotonic devices. The ways in which we apply these fabrication techniques in the field of photonics is often constrained by the technologies used for electronics manufacturing which presents an interesting engineering challenge. These limitations include availability and cost of certain fabrication equipment and techniques required to create state-of-the-art nanophotonic devices. Through work with the University of California Irvine nano-fabrication cleanroom, we designed and fabricated various integrated photonic components including grating …

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Evaluation Of The Trunarc Handheld Narcotics Analyzer As A Pre-Analysis Screening Device For The Orange County Crime Lab, Sarah Yang, D. Bauer, C. Woltz, S. Soto, Michael Ibba Dec 2021

Evaluation Of The Trunarc Handheld Narcotics Analyzer As A Pre-Analysis Screening Device For The Orange County Crime Lab, Sarah Yang, D. Bauer, C. Woltz, S. Soto, Michael Ibba

Student Scholar Symposium Abstracts and Posters

Forensic analysis of suspected narcotics is often dangerous as the substances’ composition is unknown. Many techniques for drug identification require handling of the substance outside of its packaging, which can expose the analyst to potentially harmful chemicals. The TruNarc Handheld Narcotics Analyzer is a portable Raman spectroscopy device that is non-destructive of evidence and can be used to screen drugs through simple packaging to minimize the risk of exposure. The Orange County Crime Lab (OCCL) is testing the limits of this device to determine if it can be used to screen new evidence within the Seized Drugs Lab. The OCCL …

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Quantum State Estimation And Tracking For Superconducting Processors Using Machine Learning, Shiva Lotfallahzadeh Barzili Dec 2021

Quantum State Estimation And Tracking For Superconducting Processors Using Machine Learning, Shiva Lotfallahzadeh Barzili

Computational and Data Sciences (PhD) Dissertations

Quantum technology has been rapidly growing; in particular, the experiments that have been performed with superconducting qubits and circuit QED have allowed us to explore the light-matter interaction at its most fundamental level. The study of coherent dynamics between two-level systems and resonator modes can provide insight into fundamental aspects of quantum physics, such as how the state of a system evolves while being continuously observed. To study such an evolving quantum system, experimenters need to verify the accuracy of state preparation and control since quantum systems are very fragile and sensitive to environmental disturbance. In this thesis, I look …

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Atlantic Ocean Variability And European Alps Winter Precipitation, Giuseppe Formetta, Jonghun Kam, Sahar Sadeghi, Glenn Tootle, Thomas Piechota Nov 2021

Atlantic Ocean Variability And European Alps Winter Precipitation, Giuseppe Formetta, Jonghun Kam, Sahar Sadeghi, Glenn Tootle, Thomas Piechota

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Winter precipitation (snowpack) in the European Alps provides a critical source of freshwater to major river basins such as the Danube, Rhine, and Po. Previous research identified Atlantic Ocean variability and hydrologic responses in the European Alps. The research presented here evaluates Atlantic Sea Surface Temperatures (SSTs) and European Alps winter precipitation variability using Singular Value Decomposition. Regions in the north and mid-Atlantic from the SSTs were identified as being tele-connected with winter precipitation in the European Alps. Indices were generated for these Atlantic SST regions to use in prediction of precipitation. Regression and non-parametric models were developed using the …

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Feel And Touch: A Haptic Mobile Game To Assess Tactile Processing, Ivonne Monarca, Monica Tentori, Franceli L. Cibrian Nov 2021

Feel And Touch: A Haptic Mobile Game To Assess Tactile Processing, Ivonne Monarca, Monica Tentori, Franceli L. Cibrian

Engineering Faculty Articles and Research

Haptic interfaces have great potential for assessing the tactile processing of children with Autism Spectrum Disorder (ASD), an area that has been under-explored due to the lack of tools to assess it. Until now, haptic interfaces for children have mostly been used as a teaching or therapeutic tool, so there are still open questions about how they could be used to assess tactile processing of children with ASD. This article presents the design process that led to the development of Feel and Touch, a mobile game augmented with vibrotactile stimuli to assess tactile processing. Our feasibility evaluation, with 5 children …

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Let's Read: Designing A Smart Display Application To Support Codas When Learning Spoken Language, Katie Rodeghiero, Yingying Yuki Chen, Annika M. Hettmann, Franceli L. Cibrian Nov 2021

Let's Read: Designing A Smart Display Application To Support Codas When Learning Spoken Language, Katie Rodeghiero, Yingying Yuki Chen, Annika M. Hettmann, Franceli L. Cibrian

Engineering Faculty Articles and Research

Hearing children of Deaf adults (CODAs) face many challenges including having difficulty learning spoken languages, experiencing social judgment, and encountering greater responsibilities at home. In this paper, we present a proposal for a smart display application called Let's Read that aims to support CODAs when learning spoken language. We conducted a qualitative analysis using online community content in English to develop the first version of the prototype. Then, we conducted a heuristic evaluation to improve the proposed prototype. As future work, we plan to use this prototype to conduct participatory design sessions with Deaf adults and CODAs to evaluate the …

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Spatial Distribution Of Pm2.5-Related Premature Mortality In China, Sheng Zheng, Uwe Schlink, Kin-Fai Ho, Ramesh P. Singh, Andrea Pozzer Nov 2021

Spatial Distribution Of Pm2.5-Related Premature Mortality In China, Sheng Zheng, Uwe Schlink, Kin-Fai Ho, Ramesh P. Singh, Andrea Pozzer

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

PM2.5 is a major component of air pollution in China and has a serious threat to public health. It is very important to quantify spatial characteristics of the health effects caused by outdoor PM2.5 exposure. This study analyzed the spatial distribution of PM2.5 concentration (45.9 μg/m3 national average in 2016) and premature mortality attributed to PM2.5 in cities at the prefectural level and above in China in 2016. Using the Global Exposure Mortality Model (GEMM), the total premature mortality in China was estimated to be 1.55 million persons, and the per capita mortality was 11.2 …

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Spatial Distribution Of Pm2.5-Related Premature Mortality In China, Sheng Zheng, Uwe Schlink, Kin-Fai Ho, Ramesh P. Singh, Andrea Pozzer Nov 2021

Spatial Distribution Of Pm2.5-Related Premature Mortality In China, Sheng Zheng, Uwe Schlink, Kin-Fai Ho, Ramesh P. Singh, Andrea Pozzer

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

PM2.5 is a major component of air pollution in China and has a serious threat to public health. It is very important to quantify spatial characteristics of the health effects caused by outdoor PM2.5 exposure. This study analyzed the spatial distribution of PM2.5 concentration (45.9 μg/m3 national average in 2016) and premature mortality attributed to PM2.5 in cities at the prefectural level and above in China in 2016. Using the Global Exposure Mortality Model (GEMM), the total premature mortality in China was estimated to be 1.55 million persons, and the per capita mortality was 11.2 …

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California Drought Outlooks Based On Climate Change Models’ Effects On Water Availability, Lauren Lynam, Thomas Piechota Nov 2021

California Drought Outlooks Based On Climate Change Models’ Effects On Water Availability, Lauren Lynam, Thomas Piechota

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Future streamflow in California is evaluated based on eight climate projections models and the effects on water availability. The unimpaired projected streamflow for eleven California rivers, collected from Cal-Adapt, are compared with unimpaired historical flows (1950–2015) using eight climate model projections (2020–2099) identified as representative as possible future scenarios; Warm Dry RCP 4.5, Average RCP 4.5, Cool Wet RCP 4.5, Other RCP 4.5, Warm Dry RCP 8.5, Average RCP 8.5, Cool Wet RCP 8.5, and Other RCP 8.5. Projected drought deficits (or magnitudes), durations, and intensities are statistically tested against historical values to determine significance of differences between past streamflow …

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Gravitational Wave Sensors Based On Superconducting Transducers, Armen Gulian, Joe Foreman, Vahan Nikoghosyan, Louis Sica, Pablo Abramian-Barco, Jeff Tollaksen, Gurgen Melkonyan, Iris Mowgood, Chris Burdette, Rajendra Dulal, Serafim Teknowijoyo, Sara Chahid, Shmuel Nussinov Nov 2021

Gravitational Wave Sensors Based On Superconducting Transducers, Armen Gulian, Joe Foreman, Vahan Nikoghosyan, Louis Sica, Pablo Abramian-Barco, Jeff Tollaksen, Gurgen Melkonyan, Iris Mowgood, Chris Burdette, Rajendra Dulal, Serafim Teknowijoyo, Sara Chahid, Shmuel Nussinov

Mathematics, Physics, and Computer Science Faculty Articles and Research

Following the initial success of LIGO, new advances in gravitational wave (GW) detector systems are planned to reach fruition during the next decades. These systems are interferometric and large. Here we suggest different, more compact detectors of GW radiation with competitive sensitivity. These nonresonant detectors are not interferometric. They use superconducting Cooper pairs in a magnetic field to transform mechanical motion induced by GW into detectable magnetic flux. The detectors can be oriented relative to the source of GW, so as to maximize the signal output and help determine the direction of nontransient sources. In this design an incident GW …

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Pre-Earthquake Ionospheric Perturbation Identification Using Cses Data Via Transfer Learning, Pan Xiong, Cheng Long, Huiyu Zhou, Roberto Battiston, Angelo De Santis, Dimitar Ouzounov, Xuemin Zhang, Xuhui Shen Nov 2021

Pre-Earthquake Ionospheric Perturbation Identification Using Cses Data Via Transfer Learning, Pan Xiong, Cheng Long, Huiyu Zhou, Roberto Battiston, Angelo De Santis, Dimitar Ouzounov, Xuemin Zhang, Xuhui Shen

Mathematics, Physics, and Computer Science Faculty Articles and Research

During the lithospheric buildup to an earthquake, complex physical changes occur within the earthquake hypocenter. Data pertaining to the changes in the ionosphere may be obtained by satellites, and the analysis of data anomalies can help identify earthquake precursors. In this paper, we present a deep-learning model, SeqNetQuake, that uses data from the first China Seismo-Electromagnetic Satellite (CSES) to identify ionospheric perturbations prior to earthquakes. SeqNetQuake achieves the best performance [F-measure (F1) = 0.6792 and Matthews correlation coefficient (MCC) = 0.427] when directly trained on the CSES dataset with a spatial window centered on the earthquake epicenter with the Dobrovolsky …

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Hydrological Feedbacks On Peatland Ch4 Emission Under Warming And Elevated Co2: A Modeling Study, Fenghui Yuan, Yihui Wang, Daniel M. Ricciuto, Xiaoying Shi, Fengming Yuan, Thomas Brehme, Scott Bridgham, Jason Keller, Jeffrey M. Warren, Natalie A. Griffiths, Stephen D. Sebestyen, Paul J. Hanson, Peter E. Thornton, Xiaofeng Xu Nov 2021

Hydrological Feedbacks On Peatland Ch4 Emission Under Warming And Elevated Co2: A Modeling Study, Fenghui Yuan, Yihui Wang, Daniel M. Ricciuto, Xiaoying Shi, Fengming Yuan, Thomas Brehme, Scott Bridgham, Jason Keller, Jeffrey M. Warren, Natalie A. Griffiths, Stephen D. Sebestyen, Paul J. Hanson, Peter E. Thornton, Xiaofeng Xu

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Peatland carbon cycling is critical for the land–atmosphere exchange of greenhouse gases, particularly under changing environments. Warming and elevated atmospheric carbon dioxide (eCO2) concentrations directly enhance peatland methane (CH4) emission, and indirectly affect CH4 processes by altering hydrological conditions. An ecosystem model ELM-SPRUCE, the land model of the E3SM model, was used to understand the hydrological feedback mechanisms on CH4 emission in a temperate peatland under a warming gradient and eCO2 treatments. We found that the water table level was a critical regulator of hydrological feedbacks that affect peatland CH4 dynamics; the …

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The Economics Of Residential Solar And Battery Storage: Analyzing The Impact Of The Joint Iou Proposal For Net Metering 3.0 In California, Candace E. Ybarra, Prashanth U. Nyer, John B. Broughton, Thomas A. Turk Nov 2021

The Economics Of Residential Solar And Battery Storage: Analyzing The Impact Of The Joint Iou Proposal For Net Metering 3.0 In California, Candace E. Ybarra, Prashanth U. Nyer, John B. Broughton, Thomas A. Turk

Business Faculty Articles and Research

The California Public Utilities Commission (CPUC) is currently deciding on the structure of the next net metering program, which will determine how customers who install solar panels (and battery storage) under this new program will be compensated for excess energy that they export to the grid, and the additional fees that these solar customers will have to pay. The major investor-owned utility (IOU) companies in the state and some legislators have argued that the current net metering programs are far too generous to the customers and that they create an inequity by favoring the wealthy and causing a cost shift …

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Radiocarbon Analyses Quantify Peat Carbon Losses With Increasing Temperature In A Whole Ecosystem Warming Experiment, Rachel M. Wilson, Natalie A. Griffiths, Ate Visser, Karis J. Mcfarlane, Stephen D. Sebestyen, Keith C. Oleheiser, Samantha Bosman, Anya M. Hopple, Malak M. Tfaily, Randall K. Kolka, Paul J. Hanson, Joel E. Kostka, Scott D. Bridgham, Jason K. Keller, Jeffrey P. Chanton Oct 2021

Radiocarbon Analyses Quantify Peat Carbon Losses With Increasing Temperature In A Whole Ecosystem Warming Experiment, Rachel M. Wilson, Natalie A. Griffiths, Ate Visser, Karis J. Mcfarlane, Stephen D. Sebestyen, Keith C. Oleheiser, Samantha Bosman, Anya M. Hopple, Malak M. Tfaily, Randall K. Kolka, Paul J. Hanson, Joel E. Kostka, Scott D. Bridgham, Jason K. Keller, Jeffrey P. Chanton

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Climate warming is expected to accelerate peatland degradation and release rates of carbon dioxide (CO2) and methane (CH4). Spruce and Peatlands Responses Under Changing Environments is an ecosystem-scale climate manipulation experiment, designed to examine peatland ecosystem response to climate forcings. We examined whether heating up to +9 °C to 3 m-deep in a peat bog over a 7-year period led to higher C turnover and CO2 and CH4 emissions, by measuring 14C of solid peat, dissolved organic carbon (DOC), CH4, and dissolved CO2 (DIC). DOC, a major substrate for heterotrophic respiration, increased significantly with warming. There was no 7-year trend …

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Assessing The Vertical Displacement Of The Grand Ethiopian Renaissance Dam During Its Filling Using Dinsar Technology And Its Potential Acute Consequences On The Downstream Countries, Hesham El-Askary, Amr Fawzy, Rejoice Thomas, Wenzhao Li, Nicholas Lahaye, Erik Linstead, Thomas Piechota, Daniele Struppa, Mohamed Abdelaty Sayed Oct 2021

Assessing The Vertical Displacement Of The Grand Ethiopian Renaissance Dam During Its Filling Using Dinsar Technology And Its Potential Acute Consequences On The Downstream Countries, Hesham El-Askary, Amr Fawzy, Rejoice Thomas, Wenzhao Li, Nicholas Lahaye, Erik Linstead, Thomas Piechota, Daniele Struppa, Mohamed Abdelaty Sayed

Mathematics, Physics, and Computer Science Faculty Articles and Research

The Grand Ethiopian Renaissance Dam (GERD), formerly known as the Millennium Dam, is currently under construction and has been filling at a fast rate without sufficient known analysis on possible impacts on the body of the structure. The filling of GERD not only has an impact on the Blue Nile Basin hydrology, water storage and flow but also poses massive risks in case of collapse. Rosaries Dam located in Sudan at only 116 km downstream of GERD, along with the 20 million Sudanese benefiting from that dam, would be seriously threatened in case of the collapse of GERD. In this …

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Unary-Determined Distributive ℓ -Magmas And Bunched Implication Algebras, Natanael Alpay, Peter Jipsen, Melissa Sugimoto Oct 2021

Unary-Determined Distributive ℓ -Magmas And Bunched Implication Algebras, Natanael Alpay, Peter Jipsen, Melissa Sugimoto

Mathematics, Physics, and Computer Science Faculty Articles and Research

A distributive lattice-ordered magma (dℓ-magma) (A,∧,∨,⋅) is a distributive lattice with a binary operation ⋅ that preserves joins in both arguments, and when ⋅ is associative then (A,∨,⋅) is an idempotent semiring. A dℓ-magma with a top ⊤ is unary-determined if x⋅y=(x⋅⊤∧y)∨(x∧⊤⋅y). These algebras are term-equivalent to a subvariety of distributive lattices with ⊤ and two join-preserving unary operations p, q. We obtain simple conditions on p, q such that x⋅y=(px∧y)∨(x∧qy) is associative, commutative, idempotent and/or has an identity element. This generalizes previous results on the structure of doubly idempotent semirings and, in the case when the …

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Algorithmic Correspondence For Relevance Logics, Bunched Implication Logics, And Relation Algebras Via An Implementation Of The Algorithm Pearl, Willem Conradie, Valentin Goranko, Peter Jipsen Oct 2021

Algorithmic Correspondence For Relevance Logics, Bunched Implication Logics, And Relation Algebras Via An Implementation Of The Algorithm Pearl, Willem Conradie, Valentin Goranko, Peter Jipsen

Mathematics, Physics, and Computer Science Faculty Articles and Research

The non-deterministic algorithmic procedure PEARL (acronym for ‘Propositional variables Elimination Algorithm for Relevance Logic’) has been recently developed for computing first-order equivalents of formulas of the language of relevance logics LR in terms of the standard Routley-Meyer relational semantics. It succeeds on a large class of axioms of relevance logics, including all so called inductive formulas. In the present work we re-interpret PEARL from an algebraic perspective, with its rewrite rules seen as manipulating quasi-inequalities interpreted over Urquhart’s relevant algebras, and report on its recent Python implementation. We also show that all formulae on which PEARL succeeds are canonical, i.e., …

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Cyclic Peptide-Gadolinium Nanocomplexes As Sirna Delivery Tools, Amir Nasrolahi Shirazi, Muhammad Imran Sajid, Dindyal Mandal, David Stickley, Stephanie Nagasawa, Joshua Long, Sandeep Lohan, Keykavous Parang, Rakesh Kumar Tiwari Oct 2021

Cyclic Peptide-Gadolinium Nanocomplexes As Sirna Delivery Tools, Amir Nasrolahi Shirazi, Muhammad Imran Sajid, Dindyal Mandal, David Stickley, Stephanie Nagasawa, Joshua Long, Sandeep Lohan, Keykavous Parang, Rakesh Kumar Tiwari

Pharmacy Faculty Articles and Research

We have recently reported that a cyclic peptide containing five tryptophan, five arginine, and one cysteine amino acids [(WR)5C], was able to produce peptide-capped gadolinium nanoparticles, [(WR)5C]-GdNPs, in the range of 240 to 260 nm upon mixing with an aqueous solution of GdCl3. Herein, we report [(WR)5C]-GdNPs as an efficient siRNA delivery system. The peptide-based gadolinium nanoparticles (50 µM) did not exhibit significant cytotoxicity (~93% cell viability at 50 µM) in human leukemia T lymphoblast cells (CCRF-CEM) and triple-negative breast cancer cells (MDA-MB-231) after 48 h. Fluorescence-activated cell sorting (FACS) analysis indicated …

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Prevention And Preparedness Of The Messina-Reggio Calabria Strait: An Earthquake Forecasting And Didactic Project, Francesco Di Stefano, Gioacchino Giampaolo Giuliani, Dimitar Ouzounov, Daniele Cataldi, Cristiano Fidani, Angelo D'Errico, Giulia Fioravanti Sep 2021

Prevention And Preparedness Of The Messina-Reggio Calabria Strait: An Earthquake Forecasting And Didactic Project, Francesco Di Stefano, Gioacchino Giampaolo Giuliani, Dimitar Ouzounov, Daniele Cataldi, Cristiano Fidani, Angelo D'Errico, Giulia Fioravanti

Mathematics, Physics, and Computer Science Faculty Articles and Research

This contribution is addressed to an introductive university course on the correlation existing between radon emission and earthquakes processes held following a flipped-class approach where students receive didactic materials prior to face-to-face lessons. This research was initially started to investigate the real correlation between Radon emission from the Earth and the occurrence of strong earthquakes by using measurements of hourly Radon flow variation. During quiet seismogenic conditions, we observe an unvarying level of Radon emission in the air. Before a strong earthquake, substantial variations of Radon (222Rn) concentration have been observed in the air, probably because of the …

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Oxidation Alters The Architecture Of The Phenylalanyl-Trna Synthetase Editing Domain To Confer Hyperaccuracy, Pooja Srinivas, Rebecca E. Steiner, Ian J. Pavelich, Ricardo Guerrera-Ferreira, Puneet Juneja, Michael Ibba, Christine M. Dunham Sep 2021

Oxidation Alters The Architecture Of The Phenylalanyl-Trna Synthetase Editing Domain To Confer Hyperaccuracy, Pooja Srinivas, Rebecca E. Steiner, Ian J. Pavelich, Ricardo Guerrera-Ferreira, Puneet Juneja, Michael Ibba, Christine M. Dunham

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

High fidelity during protein synthesis is accomplished by aminoacyl-tRNA synthetases (aaRSs). These enzymes ligate an amino acid to a cognate tRNA and have proofreading and editing capabilities that ensure high fidelity. Phenylalanyl-tRNA synthetase (PheRS) preferentially ligates a phenylalanine to a tRNAPhe over the chemically similar tyrosine, which differs from phenylalanine by a single hydroxyl group. In bacteria that undergo exposure to oxidative stress such as Salmonella enterica serovar Typhimurium, tyrosine isomer levels increase due to phenylalanine oxidation. Several residues are oxidized in PheRS and contribute to hyperactive editing, including against mischarged Tyr-tRNAPhe, despite these oxidized residues not …

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Atomistic Simulations And In Silico Mutational Profiling Of Protein Stability And Binding In The Sars-Cov-2 Spike Protein Complexes With Nanobodies: Molecular Determinants Of Mutational Escape Mechanisms, Gennady M. Verkhivker, Steve Agajanian, Deniz Yasar Oztas, Grace Gupta Sep 2021

Atomistic Simulations And In Silico Mutational Profiling Of Protein Stability And Binding In The Sars-Cov-2 Spike Protein Complexes With Nanobodies: Molecular Determinants Of Mutational Escape Mechanisms, Gennady M. Verkhivker, Steve Agajanian, Deniz Yasar Oztas, Grace Gupta

Mathematics, Physics, and Computer Science Faculty Articles and Research

Structure-functional studies have recently revealed a spectrum of diverse high-affinity nanobodies with efficient neutralizing capacity against SARS-CoV-2 virus and resilience against mutational escape. In this study, we combine atomistic simulations with the ensemble-based mutational profiling of binding for the SARS-CoV-2 S-RBD complexes with a wide range of nanobodies to identify dynamic and binding affinity fingerprints and characterize the energetic determinants of nanobody-escaping mutations. Using an in silico mutational profiling approach for probing the protein stability and binding, we examine dynamics and energetics of the SARS-CoV-2 complexes with single nanobodies Nb6 and Nb20, VHH E, a pair combination VHH E + …

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Generalized Grassmann Algebras And Applications To Stochastic Processes, Daniel Alpay, Paula Cerejeiras, Uwe Kaehler Sep 2021

Generalized Grassmann Algebras And Applications To Stochastic Processes, Daniel Alpay, Paula Cerejeiras, Uwe Kaehler

Mathematics, Physics, and Computer Science Faculty Articles and Research

In this paper, we present the groundwork for an Itô/Malliavin stochastic calculus and Hida's white noise analysis in the context of a supersymmetry with Z3-graded algebras. To this end, we establish a ternary Fock space and the corresponding strong algebra of stochastic distributions and present its application in the study of stochastic processes in this context.

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The Structure Of Finite Commutative Idempotent Involutive Residuated Lattices, Peter Jipsen, Olim Tuyt, Diego Valota Sep 2021

The Structure Of Finite Commutative Idempotent Involutive Residuated Lattices, Peter Jipsen, Olim Tuyt, Diego Valota

Mathematics, Physics, and Computer Science Faculty Articles and Research

We characterize commutative idempotent involutive residuated lattices as disjoint unions of Boolean algebras arranged over a distributive lattice. We use this description to introduce a new construction, called gluing, that allows us to build new members of this variety from other ones. In particular, all finite members can be constructed in this way from Boolean algebras. Finally, we apply our construction to prove that the fusion reduct of any finite member is a distributive semilattice, and to show that this variety is not locally finite.

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Emergence Of Non-Hexagonal Crystal Packing Of Deswollen And Deformed Ultra-Soft Microgels Under Osmotic Pressure Control, Molla R. Islam, Rachel Nguyen, L. Andrew Lyon Sep 2021

Emergence Of Non-Hexagonal Crystal Packing Of Deswollen And Deformed Ultra-Soft Microgels Under Osmotic Pressure Control, Molla R. Islam, Rachel Nguyen, L. Andrew Lyon

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Highly solvent swollen poly(N-isopropylacrylamide-co-acrylic acid) microgels are synthesized without exogenous crosslinker, making them extremely soft and deformable. These ultralow crosslinked microgels (ULC) are incubated under controlled osmotic pressure to provide a slow (and presumably thermodynamically controlled) approach to higher packing densities. It is found that ULC microgels show stable colloidal packing over a very wide range of osmotic pressures and thus packing densities. Surprising observation of co-existence between hexagonal and square lattices is also made over the lower range of studied osmotic pressures, with microgels apparently changing shape from spheres to cubes in defects or grain boundaries. It is proposed …

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Underground Burning Of Jharia Coal Mine (India) And Associated Surface Deformation Using Insar Data, Jungrack Kim, Shih-Yuan Lin, Ramesh P. Singh, Chen-Wei Lan, Hye-Won Yun Sep 2021

Underground Burning Of Jharia Coal Mine (India) And Associated Surface Deformation Using Insar Data, Jungrack Kim, Shih-Yuan Lin, Ramesh P. Singh, Chen-Wei Lan, Hye-Won Yun

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The underground burning in the Jharia coal mine (JCM) in India is a highly devastating environmental hazard inducing various adverse consequences. In the present study, we carried out time series analyses based on Interferometric Synthetic Aperture Radar (InSAR) and land surface temperature (LST) to study the environmental risk. First, a permanent scatterer (PS) time series analysis using Sentinel-1 images over three years was performed to detect the spatio-temporal distribution of ground deformation. Comparison of ground thermal anomaly clearly delineated the subsidence spots associated with the oxygen supply to combustion areas. On the contrary, few deformations were mapped showing pronounced uplift …

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An Examination Of Factors Influencing Small Proton Chemical Shift Differences In Nitrogen-Substituted Monodeuterated Methyl Groups, Stuart J. Elliott, O. Maduka Ogba, Lynda J. Brown, Daniel J. O'Leary Sep 2021

An Examination Of Factors Influencing Small Proton Chemical Shift Differences In Nitrogen-Substituted Monodeuterated Methyl Groups, Stuart J. Elliott, O. Maduka Ogba, Lynda J. Brown, Daniel J. O'Leary

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Monodeuterated methyl groups have previously been demonstrated to provide access to long-lived nuclear spin states. This is possible when the CH2 D rotamers have sufficiently different populations and the local environment is chiral, which foments a non-negligible isotropic chemical shift difference between the two CH2 D protons. In this article, the focus is on the N-CH2 D group of N-CH2 D-2-methylpiperidine and other suitable CH2 D piperidine derivatives. We used a combined experimental and computational approach to investigate how rotameric symmetry breaking leads to a 1H CH2 D chemical shift …

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