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Full-Text Articles in Physical Sciences and Mathematics
Polystyrene-Supported Aluminum Chloride As An Efficient And Reusable Catalyst For Condensation Of Indole With Various Carbonyl Compounds, Bahman Tamami, Amir Nasrolahi Shirazi, Kaveh Parvanak Borujeni
Polystyrene-Supported Aluminum Chloride As An Efficient And Reusable Catalyst For Condensation Of Indole With Various Carbonyl Compounds, Bahman Tamami, Amir Nasrolahi Shirazi, Kaveh Parvanak Borujeni
Pharmacy Faculty Articles and Research
Crosslinked polystyrene-supported aluminum chloride (PS-AlCl3) is a stable, recyclable and environmental friendly heterogeneous catalyst for the condensation of indole with aldehydes and ketones to afford diindolylmethanes. In addition, PS-AlCl3 shows satisfactory selectivity in the reaction of mixtures of an aldehyde and a ketone with indole. Although AlCl3 is a water sensitive, corrosive and environmentally harmful compound, PS-AlCl3 is a stable and water-tolerant species. The mild reaction conditions, short reaction times, easy work-up, high to excellent yields, chemoselectivity, reuse of the catalyst for at least ten times without significant change in its catalytic activity, low cost, and easy preparation and handling …
Major Challenges For The Modern Chemistry In Particular And Science In General, Vuk Uskoković
Major Challenges For The Modern Chemistry In Particular And Science In General, Vuk Uskoković
Pharmacy Faculty Articles and Research
In the past few hundred years, science has exerted an enormous influence on the way the world appears to human observers. Despite phenomenal accomplishments of science, science nowadays faces numerous challenges that threaten its continued success. As scientific inventions become embedded within human societies, the challenges are further multiplied. In this critical review, some of the critical challenges for the field of modern chemistry are discussed, including: (a) interlinking theoretical knowledge and experimental approaches; (b) implementing the principles of sustainability at the roots of the chemical design; (c) defining science from a philosophical perspective that acknowledges both pragmatic and realistic …