Physical Sciences and Mathematics Commons^™

Salt Gland Excretion Efficiency And Salinity Tolerance Of Sporobolus Species, Piumi Shrimani Weragodavidana

Theses

Halophytic C4 grasses, including Sporobolus species, have developed specific mechanisms to cope with salinity stress. Among these, “salt glands” which are bi- cellular leaf epidermal structures eliminating excess saline ions from shoots by excretion under salinity stress. Salt glands are morphologically visible and can potentially be used for salt tolerance breeding programs. The objectives of this study were: (1) to determine the leaf salt gland excretion rates of United Arab Emirates native halophytic chloridoid grass species, S. spicatus and S. arabicus; (2) to determine if leaf salt gland excretion rate and density can effectively predict salinity tolerance among Sporobolus genotypes, …

Characterization Of Dom And Its Interactions With Invasive Quagga Mussels In Lake Michigan, Stephen Devilbiss

Theses and Dissertations

Green Bay is the largest freshwater estuary in the Laurentian Great Lakes and receives disproportional terrestrial inputs. While seasonal hypoxia and the formation of “dead zones” in Green Bay have received increasing attention, there are no systematic studies on the dynamics of dissolved organic matter (DOM) and its linkage to the development of hypoxia. During summer 2014, bulk dissolved organic carbon (DOC) analysis, UV-vis spectroscopy, and fluorescence excitation-emission matrices (EEMs) coupled with PARAFAC analysis were used to quantify the abundance, composition and source of DOM and their spatiotemporal variations in Green Bay, Lake Michigan. Concentrations of DOC ranged from 202 …

A Physiologically-Based Pharmacokinetic Model For The Antibiotic Levofloxacin, Paezha M. Mccartt

Undergraduate Honors Theses

Levofloxacin is in a class of antibiotics known as fluoroquinolones, which treat infections by killing the bacteria that cause them. A physiologically-based pharmacokinetic (PBPK) model was developed to investigate the uptake, distribution, and elimination of Levofloxacin after a single dose. PBPK modeling uses parameters such as body weight, blood flow rates, partition coefficients, organ volumes, and several other parameters in order to model the distribution of a particular drug throughout the body. Levofloxacin is only moderately bound in human blood plasma, and, thus, for the purposes of this paper, linear bonding is incorporated into the model because the free or …

A Physiologically-Based Pharmacokinetic Model For Vancomycin, Rebekah White

Undergraduate Honors Theses

Vancomycin is an antibiotic used for the treatment of systemic infections. It is given

intravenously usually every twelve or twenty-four hours. This particular drug has a

medium level of boundedness, with approximately fty percent of the drug being free

and thus physiologically eective. A physiologically-based pharmacokinetic (PBPK)

model was used to better understand the absorption, distribution, and elimination of

the drug. Using optimal parameters, the model could be used in the future to test

how various factors, such as BMI or excretion levels, might aect the concentration

of the antibiotic.