Physical Sciences and Mathematics Commons^™

Wallaby – An Ska Pathfinder Hisurvey, B. S. Koribalski, L. Stavely-Smith, Tobias Westmeier, P. Serra, K. Spekkens, O. I. Wang, C. D. P. Lagos, D. Obreschkow, E. V. Ryan-Webber, Juan P. Madrid

Physics and Astronomy Faculty Publications and Presentations

The Widefield ASKAP L-band Legacy All-sky Blind surveY (WALLABY) is a next-generation survey of neutral hydrogen (HI) in the Local Universe. It uses the widefield, high-resolution capability of the Australian Square Kilometer Array Pathfinder (ASKAP), a radio interferometer consisting of 36 x 12-m dishes equipped with Phased-Array Feeds (PAFs), located in an extremely radio-quiet zone in Western Australia. WALLABY aims to survey three-quarters of the sky (-90 degr < Dec < +30 degr) to a redshift of z < 0.26, and generate spectral line image cubes at ~30 arcsec resolution and ~1.6 mJy/beam per 4 km/s channel sensitivity. ASKAP's instantaneous field of view at 1.4 GHz, delivered by the PAF's 36 beams, is about 30 sq deg. At an integrated signal-to-noise ratio of five, WALLABY is expected to detect over half a million galaxies with a mean redshift of z ~ 0.05 (~200 Mpc). The scientific goals of WALLABY include: (a) a census of gas-rich galaxies in the vicinity of the Local Group; (b) a study of the HI properties of galaxies, groups and clusters, in particular the influence of the environment on galaxy evolution; and (c) the refinement of cosmological parameters using the spatial and redshift distribution of low-bias gas-rich galaxies. For context we provide an overview of previous large-scale HI surveys. Combined with existing and new multi-wavelength sky surveys, WALLABY will enable an exciting new generation of panchromatic studies of the Local Universe. - First results from the WALLABY pilot survey are revealed, with initial data products publicly available in the CSIRO ASKAP Science Data Archive (CASDA).

The Acs Survey Of Galactic Globular Clusters Xiv: Bayesian Single-Population Analysis Of 69 Globular Clusters, R. Wagner-Kaiser, Ted Von Hippel, A. Sarajedini, D. C. Stenning, D. A. Van Dyck, Et Al.

Publications

We use Hubble Space Telescope (HST) imaging from the ACS Treasury Survey to determine fits for single population isochrones of 69 Galactic globular clusters. Using robust Bayesian analysis techniques, we simultaneously determine ages, distances, absorptions, and helium values for each cluster under the scenario of a \single" stellar population on model grids with solar ratio heavy element abundances. The set of cluster parameters is determined in a consistent and reproducible manner for all clusters using the Bayesian analysis suite BASE-9. Our results are used to re-visit the age-metallicity relation. We find correlations with helium and several other parameters such as …

Iron Concretions In The Cretaceous Dakota Formation, Anthony Kohtz, Richard Kettler, David Loope

UCARE Research Products

The Cretaceous Dakota Formation contains abundant iron oxide concretions. The precursors to the iron concretions are siderite (FeCO3) nodules that formed in a reducing floodplain environment. A variety of concretion morphologies formed when the precursor siderite nodules were dissolved by oxidizing groundwater in a paleoaquifer. Iron-oxidizing bacteria are able to oxidize aqueous Fe(II) to Fe(III) oxy-hydroxide at microaerophilic and neutrophilic conditions. This study investigated these concretions to determine if there was a microbial element in their formation and to characterize the concretion morphologies present in the Dakota. This is important for complete paleoenvironment interpretations and astrobiology pursuits.

Comment On "Cycling Li-O2 Batteries Via Lioh Formation And Decomposition", Yue Shen, Wang Zhang, Shulei Chou, S X. Dou

Australian Institute for Innovative Materials - Papers

Copyright 2016 by the American Association for the Advancement of Science; all rights reserved. Liu et al. (Research Article, 30 October 2015, p. 530) described a lithium-oxygen (Li-O2) battery based on lithium iodide (LiI)-assisted lithium hydroxide (LiOH) formation and decomposition.We argue that LiOH cannot be oxidized by triiodide (I3 -). The charge capacity is from the oxidation of I- instead of LiOH. The limited-capacity cycling test is misleading when the electrolyte contributes considerable parasitic reaction capacity.

Detailed Source-Specific Molecular Composition Of Ambient Aerosol Organic Matter Using Ultrahigh Resolution Mass Spectrometry And H Nmr, Amanda S. Willoughby, Andrew S. Wozniak, Patrick G. Hatcher

Chemistry & Biochemistry Faculty Publications

Organic aerosols (OA) are universally regarded as an important component of the atmosphere that have far-ranging impacts on climate forcing and human health. Many of these impacts are related to OA molecular characteristics. Despite the acknowledged importance, current uncertainties related to the source apportionment of molecular properties and environmental impacts make it difficult to confidently predict the net impacts of OA. Here we evaluate the specific molecular compounds as well as bulk structural properties of total suspended particulates in ambient OA collected from key emission sources (marine, biomass burning, and urban) using ultrahigh resolution mass spectrometry (UHR-MS) and proton nuclear …

The Inferred Evolution Of The Cold Gas Properties Of Candels Galaxies At 0.5 < Z < 3.0, G. Popping, K. Caputi, S. C. Trager, Rachel S. Somerville, Avishai Dekel, Susan A. Kassin, Dale D. Kocevski, Anton M. Koekemoer, Sandra M. Faber, Henry C. Ferguson, A. Galametz, Norman A. Grogin, Yicheng Guo, Y. Lu, Arjen Van Der Wel, Benjamin J. Weiner

Physics and Astronomy Faculty Publications

We derive the total cold gas, atomic hydrogen, and molecular gas masses of approximately 24 000 galaxies covering four decades in stellar mass at redshifts 0.5 < z < 3.0, taken from the Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey survey. Our inferences are based on the inversion of a molecular hydrogen based star formation law, coupled with a prescription to separate atomic and molecular gas. We find that: (1) there is an increasing trend between the inferred cold gas (H i and H₂), H i, and H₂ mass and the stellar mass of galaxies down to stellar masses of 10⁸ M_⊙ already in place at z = 3; (2) the molecular fractions of cold gas increase with increasing stellar mass and look-back time; (3) there is hardly any evolution in the mean H i content of galaxies at fixed stellar mass; (4) the cold gas fraction and relative amount of molecular …

Observational Properties Of Simulated Galaxies In Overdense And Average Regions At Redshifts Z ≃ 6–12, Hidenobu Yajima, Isaac Shlosman, Emilio Romano-Díaz, Kentaro Nagamine

Physics and Astronomy Faculty Publications

We use high-resolution zoom-in cosmological simulations of galaxies of Romano-Díaz et al., post-processing them with a panchromatic three-dimensional radiation transfer code to obtain the galaxy UV luminosity function (LF) at z ≃ 6–12. The galaxies are followed in a rare, heavily overdense region within a ∼5σ density peak, which can host high-z quasars, and in an average density region, down to the stellar mass of M_star ∼ 4 × 10⁷ M_⊙. We find that the overdense regions evolve at a substantially accelerated pace – the most massive galaxy has grown to M_star ∼ 8.4 …

Supermassive Black Hole Formation At High Redshifts Via Direct Collapse In A Cosmological Context, Jun-Hwan Choi, Isaac Shlosman, Mitchell C. Begelman

Physics and Astronomy Faculty Publications

We study the early stage of the formation of seed supermassive black holes via direct collapse in dark matter (DM) haloes, in the cosmological context. We perform high-resolution zoom-in simulations of such collapse at high z. Using the adaptive mesh refinement code enzo, we resolve the formation and growth of a DM halo, until its virial temperature reaches ∼10⁴ K, atomic cooling turns on, and collapse ensues. We demonstrate that direct collapse proceeds in two stages, although they are not well separated. The first stage is triggered by the onset of atomic cooling, and leads to rapidly increasing …

Star Formation And Quenching Among The Most Massive Galaxies At Z ∼ 1.7, C. Mancini, A. Renzini, E. Daddi, G. Rodighiero, S. Berta, N. Grogin, Dale D. Kocevski, A. Koekemoer

Physics and Astronomy Faculty Publications

We have conducted a detailed object-by-object study of a mass-complete (M_* ≥ 10¹¹ M_⊙) sample of 56 galaxies at 1.4 ≤ z ≤ 2 in the Great Observatories Origins Deep Survey-South field, showing that an accurate deblending in 24 μm images is essential to properly assign to each galaxy its own star formation rate (SFR), whereas an automatic procedure often fails. This applies especially to galaxies with SFRs below the main sequence (MS) value, which may be in their quenching phase. After that, the sample splits evenly between galaxies forming stars within a factor of …

P-Manga: Gradients In Recent Star Formation Histories As Diagnostics For Galaxy Growth And Death, Cheng Li, Enci Wang, Lin Lin, Matthew A. Bershady, Kevin Bundy, Christy A. Tremonti, Ting Xiao, Renbin Yan, Dmitry Bizyaev, Michael Blanton, Sabrina Cales, Brian Cherinka, Edmond Cheung, Niv Drory, Eric Emsellem, Hai Fu, Joseph Gelfand, David R. Law, Lahwai Lin, Nick Macdonald, Claudia Maraston, Karen L. Masters, Michael R. Merrifield, Kaike Pan, S. F. Sánchez, Donald P. Schneider, Daniel Thomas, David Wake, Lixin Wang, Anne-Marie Weijmans, David Wilkinson, Peter Yoachim, Kai Zhang, Tiantian Zheng

Physics and Astronomy Faculty Publications

We present an analysis of the data produced by the MaNGA prototype run (P-MaNGA), aiming to test how the radial gradients in recent star formation histories, as indicated by the 4000 Å break (D_n(4000)), Hδ absorption (EW(Hδ_A)), and Hα emission (EW(Hα)) indices, can be useful for understanding disk growth and star formation cessation in local galaxies. We classify 12 galaxies observed on two P-MaNGA plates as either centrally quiescent (CQ) or centrally star-forming (CSF), according to whether D_n(4000) measured in the central spaxel of each datacube exceeds 1.6. For …

P-Manga: Full Spectral Fitting And Stellar Population Maps From Prototype Observations, David M. Wilkinson, Claudia Maraston, Daniel Thomas, Lodovico Coccato, Rita Tojeiro, Michele Cappellari, Francesco Belfiore, Matthew Bershady, Mike Blanton, Kevin Bundy, Sabrina Cales, Brian Cherinka, Niv Drory, Eric Emsellem, Hai Fu, David Law, Cheng Li, Roberto Maiolino, Karen Masters, Christy Tremonti, David Wake, Enci Wang, Anne-Marie Weijmans, Ting Xiao, Renbin Yan, Kai Zhang, Dmitry Bizyaev, Jonathan Brinkmann, Karen Kinemuchi, Daniel Oravetz, Kaike Pan, Audrey Simmons

Physics and Astronomy Faculty Publications

MaNGA (Mapping Nearby Galaxies at Apache Point Observatory) is a 6-yr SDSS-IV (Sloan Digital Sky Survey IV) survey that will obtain resolved spectroscopy from 3600 to 10 300 Å for a representative sample of over 10 000 nearby galaxies. In this paper, we derive spatially resolved stellar population properties and radial gradients by performing full spectral fitting of observed galaxy spectra from P-MaNGA, a prototype of the MaNGA instrument. These data include spectra for 18 galaxies, covering a large range of morphological type. We derive age, metallicity, dust, and stellar mass maps, and their radial gradients, using high spectral-resolution stellar …

Measurement Of The Formation Rate Of Muonic Hydrogen Molecules, V. A. Andreev, T. I. Banks, R. M. Carey, T. A. Case, S. M. Clayton, K. M. Crowe, J. Deutsch, J. Egger, S. J. Freedman, V. A. Ganzha, Tim Gorringe, F. E. Gray, D. W. Hertzog, M. Hildebrandt, P. Kammel, B. Kiburg, S. Knaack, P. A. Kravtsov, A. G. Krivshich, B. Lauss, K. R. Lynch, E. M. Maev, O. E. Maev, F. Mulhauser, C. Petitjean, G. E. Petrov, R. Prieels, G. N. Schapkin, G. G. Semenchuk, M. A. Soroka, Vladimir Tishchenko, A. A. Vasilyev, A. A. Vorobyov, M. E. Vznuzdaev, P. Winter

Physics and Astronomy Faculty Publications

Background: The rate λ_ppμ characterizes the formation of ppμ molecules in collisions of muonic pμ atoms with hydrogen. In measurements of the basic weak muon capture reaction on the proton to determine the pseudoscalar coupling g_P, capture occurs from both atomic and molecular states. Thus knowledge of λ_ppμ is required for a correct interpretation of these experiments.

Purpose: Recently the MuCap experiment has measured the capture rate Λ_S from the singlet pμ atom, employing a low-density active target to suppress ppμ formation [V. Andreev et al. (MuCap Collaboration), Phys. Rev. Lett. 110, 012504 (2013) …

Deconstructing The Galaxy Stellar Mass Function With Ukidss And Candels: The Impact Of Colour, Structure And Environment, Alice Mortlock, Christopher J. Conselice, William G. Hartley, Ken Duncan, Caterina Lani, Jamie R. Owensworth, Omar Almaini, Arjen Van Der Wel, Kuang-Han Huang, Matthew L.N. Ashby, S. P. Willner, Adriano Fontana, Avishai Dekel, Anton M. Koekemoer, Harry C. Ferguson, Sandra M. Faber, Norman A. Grogin, Dale D. Kocevski

Physics and Astronomy Faculty Publications

We combine photometry from the Ultra Deep Survey (UDS), Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey (CANDELS) UDS and CANDELS the Great Observatories Origins Deep Survey-South (GOODS-S) surveys to construct the galaxy stellar mass function probing both the low- and high-mass end accurately in the redshift range 0.3 < z < 3. The advantages of using a homogeneous concatenation of these data sets include meaningful measures of environment in the UDS, due to its large area (0.88 deg²), and the high-resolution deep imaging in CANDELS (H₁₆₀ > 26.0), affording us robust measures of structural parameters. We construct stellar mass functions for the entire sample as parametrized by the Schechter function, and find that there is a decline in the values of ϕ and of α with …

The Mass Evolution Of The First Galaxies: Stellar Mass Functions And Star Formation Rates At 4 < Z < 7 In The Candels Goods-South Field, K. Duncan, C. J. Conselice, A. Mortlock, W. G. Hartley, Y. Guo, H. C. Ferguson, R. Davé, Y. Lu, J. Owensworth, M. L. N. Ashby, A. Dekel, M. Dickinson, S. Faber, M. Giavalisco, N. Grogin, Dale D. Kocevski, A. Koekemoer, R. S. Somerville, C. E. White

Physics and Astronomy Faculty Publications

We measure new estimates for the galaxy stellar mass function and star formation rates for samples of galaxies at z ∼ 4, 5, 6 and 7 using data in the CANDELS GOODS South field. The deep near-infrared observations allow us to construct the stellar mass function at z ≥ 6 directly for the first time. We estimate stellar masses for our sample by fitting the observed spectral energy distributions with synthetic stellar populations, including nebular line and continuum emission. The observed UV luminosity functions for the samples are consistent with previous observations; however, we find that the observed M_{UV …}

The Violent Youth Of Bright And Massive Cluster Galaxies And Their Maturation Over 7 Billion Years, B. Ascaso, B. C. Lemaux, L. M. Lubin, R. R. Gal, Dale D. Kocevski, N. Rumbaugh, G. Squires

Physics and Astronomy Faculty Publications

In this study, we investigate the formation and evolution mechanisms of the brightest cluster galaxies (BCGs) over cosmic time. At high redshift (z ∼ 0.9), we selected BCGs and most massive cluster galaxies (MMCGs) from the Cl1604 supercluster and compared them to low-redshift (z ∼ 0.1) counterparts drawn from the MCXC meta-catalogue, supplemented by Sloan Digital Sky Survey imaging and spectroscopy. We observed striking differences in the morphological, colour, spectral, and stellar mass properties of the BCGs/MMCGs in the two samples. High-redshift BCGs/MMCGs were, in many cases, star-forming, late-type galaxies, with blue broad-band colours, properties largely absent amongst …

Slides: Best Management Practices For Oil And Gas Development And Comparative Water Quality Database Of Regulations Relating To Shale Oil And Gas, Matt Samelson, University Of Colorado Boulder. Getches-Wilkinson Center For Natural Resources, Energy, And The Environment. Intermountain Oil And Gas Bmp Project

Fracking, Water Quality and Public Health: Examining Current Laws and Regulations (March 20)

Presenter: Matt Samelson, J.D., Attorney, Consultant for Intermountain Oil and Gas Best Management Practices (BMP) Project, Getches-Wilkinson Center for Natural Resources, Energy and the Environment, University of Colorado Law School

34 slides

Formation And Processability Of Liquid Crystalline Dispersion Graphene Oxide, Rouhollah Jalili, Seyed Hamed Aboutalebi, Dorna Esrafilzadeh, Konstantin Konstantinov, Joselito M. Razal, Simon E. Moulton, Gordon G. Wallace

Australian Institute for Innovative Materials - Papers

Rational control over the formation and processability, and consequently final properties of graphene oxide liquid crystalline dispersions has been a long-standing goal in the development of bottom-up device fabrication processes. Here we report, the principal conditions through which such levels of control can be exercised to fine-tune dispersion properties for further processing.

The Formation Of Nano-Layered Grains And Their Enhanced Superconducting Transition Temperature In Mg-Doped Fese0.9 Bulks, Feng Lan, Zongqing Ma, Yongchang Liu, Ning Chen, Qi Cai, Huijun Li, Shaon Barua, Dipakkumar Patel, Md Shahriar Hossain, Jung Ho Kim, S X. Dou

Australian Institute for Innovative Materials - Papers

To search a proper dopant to further improve superconductivity in 11 type Fe-based superconductors makes sense to both their superconductivity mechanism and possible technological applications. In present work, Mg doped FeSe polycrystalline bulks were obtained by a two-step solid-state reaction method. Even though there are many MgSe and iron impurities existing in the Mg heavy doped FeSe bulks, they exhibit obviously increased T_c compared to undoped FeSe sample. It was found that Mg addition has little effect on the crystal lattice parameters of superconducting beta-FeSe, whereas leads to the formation of nano-layered grain structure consisted of MgSe and beta-FeSe …

Thermoelectric Properties Of Ca3co4o9 And Ca2.8bi0.2co4o9 Thin Films In Their Island Formation Mode, Priyanka Jood, Germanas Peleckis, Xiaolin Wang, S X. Dou

Australian Institute for Innovative Materials - Papers

Ca3Co4O9 and Ca2.8Bi 0.2Co4O9 thin films were fabricated on LaAlO3 (LAO) substrate using pulsed laser deposition technique and were studied for their thermoelectric (TE) properties in Stranski-Krastanov mode for the first time. The thin films consisted of 3D clusters/islands on a 14-nm thick 2D layer with cluster density being higher for Ca 2.8Bi0.2Co4O9 thin films. The clusters also represent areas of dislocation and therefore act as carrier scattering centers, which leads to a temperature-activated type conductivity. Seebeck coefficient as high as 136 and 163 u V/K was measured for the Ca 3Co4O9 and Ca2.8Bi 0.2Co4O9 thin films, respectively, which is …

Modelling Pattern Formation In Plants, M P. Edwards, S Pereverzyev, R S. Anderssen

Faculty of Informatics - Papers (Archive)

Performing simulations with simple models is a key activity in the recovery of information about the mechanisms which underlie the observed dynamics of biological processes, such as the posi- tioning of the hairs (trichomes) on the leaves of plants. The discovery of a robust representative model is a highly non-trivial process. Without appropriate constraints to regularize the choice of a model, the non-uniqueness of possibilities is vast. As acknowledged by Young (1983) in his modelling of pea leaf development, the degree of non-uniqueness can be reduced by constraining the model to reproduce the patterns observed in mutants as well as …

Communication: New Insight Into The Barrier Governing Co2 Formation From Oh + Co, Christopher J. Johnson, Berwyck L. Poad, Ben B. Shen, Robert E. Continetti

Faculty of Science - Papers (Archive)

Despite its relative simplicity, the role of tunneling in the reaction OH + CO → H + CO(2) has eluded the quantitative predictive powers of theoretical reaction dynamics. In this study a one-dimensional effective barrier to the formation of H + CO(2) from the HOCO intermediate is directly extracted from dissociative photodetachment experiments on HOCO and DOCO. Comparison of this barrier to a computed minimum-energy barrier shows that tunneling deviates significantly from the calculated minimum-energy pathway, predicting product internal energy distributions that match those found in the experiment and tunneling lifetimes short enough to contribute significantly to the overall reaction. …

Alunite Formation Within Silica Stalactites From The Sydney Region, South-Eastern Australia, Robert A. Wray

Faculty of Science - Papers (Archive)

"This paper presents X-ray diffraction and SEM evidence for the formation of alunite, and possibly small quantities of natroalunite, within opal-A stalactites formed on quartz sandstone near Sydney in south-eastern, Australia. Alunite has been reported as a speleogenetic mineral from sediments within a number of caves around the world, but this is believed to be the first report of speleothemic alunite in opaline silica speleothems. Individual alunite crystals have not been visually identified, but SEM X-ray element mapping suggests the alunite has formed amongst kaolinite clay. Sedimentary alunite and natroalunite formation is usually associated with the reaction of sulphuric acid …

Wet Chemical Routes To The Assembly Of Organic Monolayers On Silicon Surfaces Via The Formation Of Si-C Bonds: Surface Preparation, Passivation And Functionalization, Simone Ciampi, Jason Brian Harper, J Justin Gooding

Australian Institute for Innovative Materials - Papers

Organic functionalization of non-oxidized silicon surfaces, while allowing for robust chemical passivation of the inorganic substrate, is intended and expected to broaden the chemical, physical and electronic properties of the currently most relevant technological material. Numerous protocols are now available for the preparation of Si-C, Si-O and Si-N bound layers. In particular, the covalent attachment of 1-alkenes and 1-alkynes onto hydride-terminated Si(100) and Si(111) has seen a wealth of research activity starting from the pioneering work of Linford and Chidsey (Alkyl monolayers covalently bonded to silicon surfaces, J. Am. Chem. Soc., 1993, 115(26), 12631-12632). This critical review aims to bring …

Alphab-Crystallin Inhibits The Cell Toxicity Associated With Amyloid Fibril Formation By Kappa-Casein And The Amyloid-Beta Peptide, Francis C. Dehle, Heath Ecroyd, Ian F. Musgrave, John A. Carver

Faculty of Science - Papers (Archive)

Amyloid fibril formation is associated with diseases such as Alzheimer’s, Parkinson’s, and prion diseases. Inhibition of amyloid fibril formation by molecular chaperone proteins, such as the small heat-shock protein αB-crystallin, may play a protective role in preventing the toxicity associated with this form of protein misfolding. Reduced and carboxymethylated κ-casein (RCMκ-CN), a protein derived from milk, readily and reproducibly forms fibrils at physiological temperature and pH. We investigated the toxicity of fibril formation by RCMκ-CN using neuronal model PC12 cells and determined whether the inhibition of fibril formation altered its cell toxicity. To resolve ambiguities in the literature, we also …

Carboxymethylated-K-Casein: A Convenient Tool For The Identification Of Polyphenolic Inhibitors Of Amyloid Fibril Formation, John A. Carver, Peter J. Duggan, Heath Ecroyd, Yanqin Liu, Adam G. Meyer, C E. Tranberg

Faculty of Science - Papers (Archive)

Reduced and carboxymethylated-κ-casein (RCM-κ-CN) is a milk-derived amyloidogenic protein that readily undergoes nucleation-dependent aggregation and amyloid fibril formation via a similar pathway to disease-specific amyloidogenic peptides like amyloid beta (Aβ), which is associated with Alzheimer’s disease. In this study, a series of flavonoids, many known to be inhibitors of Aβ fibril formation, were screened for their ability to inhibit RCM-κ-CN fibrilisation, and the results were compared with literature data on Aβ inhibition. Flavonoids that had a high degree of hydroxylation and molecular planarity gave good inhibition of RCM-κ-CN fibril formation. IC50 values were between 10- and 200-fold higher with RCM-κ-CN …

Protein Chemistry Of Amyloid Fibrils And Chaperones: Implications For Amyloid Formation And Disease, Justin J. Yerbury, Janet R. Kumita

Faculty of Science - Papers (Archive)

Understanding the mechanisms by which amyloid fibrils are formed, both in vivo and in vitro, is vital for developing methods to treat and prevent debilitating deposition diseases such as Alzheimer's disease, Parkinson's disease, type II diabetes and systemic amyloidoses. In recent years, computer modelling and biophysical studies have broadened our understanding of the biochemical mechanisms underpinning protein aggregation. As a result, it is now believed that the ability to form fibrils is an intrinsic property of polypeptide chains and not isolated to disease-related proteins or peptides. Molecular chaperones are a diverse group of functionally related proteins well known for their …

The Dissociated Form Of Kappa-Casein Is The Precursor To Its Amyloid Fibril Formation, Heath Ecroyd, David Thorn, Yanqin Liu, John Carver

Faculty of Science - Papers (Archive)

Bovine milk kappa-casein forms a self-associating oligomeric micelle-like species, in equilibrium with dissociated forms. In its native form, intra- and inter-molecular disulfide bonds lead to the formation of multimeric species ranging from monomers to decamers. When incubated under conditions of physiological pH and temperature, both reduced and non-reduced kappa-casein form highly structured beta-sheet amyloid fibrils. We investigated whether the precursor to kappa-casein fibril formation is a dissociated state of the protein or its oligomeric micelle-like form. We show that reduced kappa-casein is capable of forming fibrils well below its critical micelle concentration, i.e. at concentrations where only dissociated forms of …

The Two-Faced Nature Of Small Heat Shock Proteins: Amyloid Assembly And The Inhibition Of Fibril Formation. Relevance To Disease States, Heath W. Ecroyd, S Meehan, John A. Carver

Faculty of Science - Papers (Archive)

The ability of small heat-shock proteins (sHsps) such as alphaB-crystallin to inhibit the amorphous (disordered) aggregation of varied target proteins in a chaperone-like manner has been well described. The mechanistic details of this action are not understood. Amyloid fibril formation is an alternative off-folding pathway that leads to highly ordered beta-sheet-containing aggregates. Amyloid fibril formation is associated with a broad range of protein conformational diseases such as Alzhiemer's, Parkinson's and Huntington's and sHsp expression is elevated in the protein deposits that are characteristic of these disease states. The ability of sHsps to prevent fibril formation has been less well characterised. …

Phase Formation And Magnetotransport Of Alkali Metal Doped Na0.75coo2 Thermoelectric Oxide, Priyanka Jood, Germanas Peleckis, Xiaolin Wang, S X. Dou, H Yamauchi, M Karppinen

Australian Institute for Innovative Materials - Papers

Synthesis and characterization of bulk Na_xCoO₂ samples substituted by K and Rb is reported. Phase formation studies revealed a narrow stable region for Na-alkali metal-Co system. Whisker and platelike single crystalline structures have been found to form on the surface of the pellets in case of K doping. All samples were metallic and no characteristic anomaly in R-T curves was observed for Rb doped sample. Magnetoresistance measured has a pronounced positive response only for K-doped and pure Na_xCoO₂ phases, reaching 11% and 7% at 5 K temperature, respectively.

The Acs Survey Of Galactic Globular Clusters. Vii. Relative Ages, Antonio Marín-Franch, Antonio Aparicio, Giampaolo Piotto, Alfred Rosenberg, Brian Chaboyer

Dartmouth Scholarship

The ACS Survey of Galactic globular clusters is a Hubble Space Telescope Treasury program designed to provide a new large, deep, and homogeneous photometric database. Based on observations from this program, we have measured precise relative ages for a sample of 64 Galactic globular clusters by comparing the relative position of the clusters' main-sequence (MS) turnoffs, using MS fitting to cross-compare clusters within the sample. This method provides relative ages to a formal precision of 2%-7%. We demonstrate that the calculated relative ages are independent of the choice of theoretical model. We find that the Galactic globular cluster sample can …