Physical Sciences and Mathematics Commons^™

Modification Of Mof-5 Hydrostability For Peptide Absorption Studies, Margareta E. Nivision, Zachary L. Mensinger

Undergraduate Research Symposium 2015

Metal-organic frameworks (MOFs) are an intriguing class of hybrid materials that consist of infinite crystalline lattices formed by metal ions bridged by organic linkers. Their porous interiors have highly variable properties, depending on the metal ions and linkers used. To date, MOFs have primarily been examined for uses such as gas separation and storage and catalysis, but recently researchers have described the adsorption of proteins and peptides, such as cytochrome C and a trypsin digest of bovine serum albumin, in MOF pores. The MOF pore provides a stable, ordered environment in which to isolate and characterize peptides. Our research thus …