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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

A Computational Approach To Studying The Properties Of Photosensitizers In Photodynamic Therapy, Keenan Komoto May 2017

A Computational Approach To Studying The Properties Of Photosensitizers In Photodynamic Therapy, Keenan Komoto

Graduate Student Symposium

Cancer has long been a significant problem that has affected our world’s population for years and continues to this day. With the number of cases expected to increase annually there is a societal pressure to find effective treatment methods for eliminating cancer. Current forms of cancer treatment tend to cause detrimental effects to the human body and are usually quite expensive and long lasting, some costing upwards of $30,000 over an 8 week period. A more recently established form of cancer treatment known as photodynamic therapy is an effective treatment option for ridding cancers that lie on or just below …


Substrate Analogs For Characterizing The Substrate Tolerance Of S. Pneumoniae Srta, Orion Banks May 2017

Substrate Analogs For Characterizing The Substrate Tolerance Of S. Pneumoniae Srta, Orion Banks

Graduate Student Symposium

Bacterial sortases have been widely studied for their usefulness in protein modification, however, the variable substrate specificity and activity between homologs of these enzymes is not yet fully characterized. To attempt to further understand sorting signal recognition, we are working towards a substrate bound structure of sortase A from Streptococcus pneumoniae (SrtApneu). This enzyme displays a wide tolerance for alternate amino acids within the canonical LPXTG sorting motif. Our strategy involves a non-cleavable substrate analog that can be docked into the active site, allowing for elucidation of a structure displaying the key contacts that allow the enzyme …


Red Beetl: Recipe Encoder Decoder Beer Translator Lstm, Grace Ermi, Ellyn Ayton May 2017

Red Beetl: Recipe Encoder Decoder Beer Translator Lstm, Grace Ermi, Ellyn Ayton

Graduate Student Symposium

The number of craft breweries has exploded in last decade: there are around a dozen breweries in Bellingham alone. Each brewery must assemble a lineup of beers, but this process of designing new beers usually relies on some combination of brewer instinct and trial and error. Because brewing beer involves complicated biological and chemical processes, the mapping from recipe to the beer it will produce is non-trivial to predict. In this project, we consider mapping between representations of beer in three distinct domains. In one view, a beer can be described by a recipe, which specifies the particular hop, malt …


Performance Of Liquid Benzoxazine-Peg Blend Resin Systems For Potential Industrial Composites Processing, Emily Brown May 2017

Performance Of Liquid Benzoxazine-Peg Blend Resin Systems For Potential Industrial Composites Processing, Emily Brown

Graduate Student Symposium

The manufacturing of technology and materials based on benzoxazine resin is limited by melt or solvent-based processing in which benzoxazine monomer is either dissolved in a solvent or melted to transfer onto fiberglass or carbon fiber. Solvent based processing depends on the use of organic solvents which impart health and financial risks. Benzoxazine monomer also suffers from high curing temperatures where the benzoxazine polymerizes to form structures with desirable mechanical and thermal properties. Non-flammable liquid benzoxazine resin with low curing temperatures are attractive for their exclusion of organic solvents and ease of processing. In this study three series of blends …


Recognition, Internalization, Growth: Intuitive Design For Archival Representation, Jaime L. Ganzel May 2017

Recognition, Internalization, Growth: Intuitive Design For Archival Representation, Jaime L. Ganzel

Graduate Student Symposium

Although there is a pressing need for archival description and access systems to be more intuitive and user-friendly, the uniqueness of archival records presents significant barriers to establishing simplistic and standardized conventions for the representation of archival materials. Indecipherable finding aids and access tools prevent new and inexperienced researchers from accessing the unique information and documentation held in archives. This article aims to help open the archival record to new and non-traditional archival users, support individual development of archival literacy skills, and cultivate a greater level of archival awareness in our society by developing a usable model for archivists to …