Physical Sciences and Mathematics Commons^™

Peptidomic Analysis Of Skin Secretions Supports Separate Species Status For The Tailed Frogs, Ascaphus Truei And Ascaphus Montanus, J. Michael Conlon, Catherine R. Bevier, Laurent Coquet, Jérôme Leprince, Thierry Jouenne, Hubert Vaudry, Blake R. Hossack

United States Geological Survey: Staff Publications

The tailed frog Ascaphus truei Stejneger, 1899 is the most primitive extant anuran and the sister taxon to the clade of all other living frogs. The species occupies two disjunct ranges in the Northwest region of North America: the Cascade Mountains and coastal area from British Columbia to Northern California, and an inland range in the northern Rocky Mountains and the Blue andWallowa mountains. A previous study led to the isolation of eight peptides with antimicrobial activity (termed the ascaphins) from skin secretions of A. truei from the coastal range. The present study has used peptidomic analysis to identify the …