Physical Sciences and Mathematics Commons^™

A Small Area Simulation Approach To Determining Variation In Dental Procedure Rates, Paula Diehr

Paula Diehr

All small area analyses need to compare the observed variability in rates to that expected by chance alone, but the expected variability is usually not known. This paper uses patient-level data for five dental procedures to simulate the distributions of the summary statistics that are usually generated in such studies. These statistics are found to vary greatly even under the "null hypothesis" that all dentists are using procedures at the same rates. The simulated dentist rates are compared to observed rates obtained in a different study. These findings illustrate problems that can occur in small area analysis studies, and emphasize …

Use Of A Preferred Provider Plan By Employees Of The City Of Seattle, Paula Diehr

Paula Diehr

Little is known about the use of services in a preferred provider organization (PPO). We studied a preferred provider arrangement between Pacific Medical Center and employees of the City of Seattle. In the second 12 months of this program 8,529 subjects submitted at least one claim; of these, only 420 (4.9%) ever used the preferred provider. Those who used the PPO at least once differed significantly from those who never used it on age, sex, employee/dependent status, and utilization in the previous year. Outpatient and total charges were higher for PPO users than for nonusers before and after control for …

Remarks On Tensor Operators, Daniel Flath

Daniel Flath

No abstract provided.

General Relativity Is Dead, Milan Meszaros

Milan Meszaros physicist

The intent of the present study is to analize standard cosmology in an immanent mathematical-critical way. First of all, the fundamental statements of this cosmological model will be investigated themselves as well as their relevation to the theory. Further aims are to reveal the interdependence of different physical disciplines, confrontation of various observations, to elucidate the correlations between observed data and theory and, finally, to analyze this cosmology from the point of view of self-consistency.

The study discusses the status of the standard modell.

What Is Too Much Variation? The Null Hypothesis In Small-Area Analysis, Paula Diehr

Paula Diehr

A small-area analysis (SAA) in health services research often calculates surgery rates for several small areas, compares the largest rate to the smallest, notes that the difference is large, and attempts to explain this discrepancy as a function of service availability, physician practice styles, or other factors. SAAs are often difficult to interpret because there is little theoretical basis for determining how much variation would be expected under the null hypothesis that all of the small areas have similar underlying surgery rates and that the observed variation is due to chance. We developed a computer program to simulate the distribution …

Visions Of Infinity: Design And Pattern In Oriental Carpets, Carol Bier

Carol Bier

No abstract provided.

Cirrhosis In The Trauma Victim --- Effect On Mortality-Rates, Glen Tinkoff, Michael Rhodes, Daniel Diamond, Joseph F. Lucke

Joseph Lucke

To evaluate the impact cirrhosis has on survival the records of 40 cirrhotic trauma victims from the registries of two Level 1 trauma centers were reviewed and probability of survival calculated using the TRISS methodology. Mechanism of injury, anatomic location, involvement of single or multiple sites, presence of ascites, elevations in serum glutamic oxaloacetic transaminase (SGOT), alkaline phosphatase, serum bilirubin, prothrombin time (PT), and hypoalbuminemia were tabulated for each patient. Contingency tables were created for injury and hepatic parameters, as related to survival, and subjected to chi square analysis. Loglinear analysis was performed on all significant parameters to evaluate the …

Positive Residues Involved In The Voltage-Gating Of The Mitochondrial Porin-Channel Are Localized In The External Moiety Of The Pore, Philadelphia University

Philadelphia University, Jordan

No abstract provided.

Have You Hugged Your Computer Today?, David Morgan Lochhead

Dr. David Morgan Lochhead

"I have owned a computer for over ten years now. When the computer came into my life, it turned it upside down. I was excited. I would spend every moment that I could with my computer. The most exciting thing that could happen to me would be for a new piece of software to come along. I lavished my computer with new programs. "

Hyperfine Structure Of The Mnh X 7-Sigma(+) State: A Large Gas-To-Matrix Shift In The Fermi Contact Interaction, Thomas Varberg, R. Field, A. Merer

Thomas D. Varberg

No abstract provided.

Inhomogeneous Broadening In Spectral Bands Of Carbonmonoxymyoglobin: The Connection Between Spectral And Functional Heterogeneity, Todd B. Sauke, P. Ormos, A. Ansari, D. Braunstein, B. R. Cowen, H. Fraunfelder, M. K. Hong, I. E. T. Iben, P. J. Steinbach, R. D. Young

Todd B. Sauke

The rebinding kinetics of CO to myoglobin after flash photolysis is nonexponential in time below approximately 180 K; the kinetics is governed by a distribution of enthalpic barriers. This distribution results from inhomogeneities in the protein conformation, referred to as conformational substates. Hole-burning experiments on the Soret and IR CO-stretch bands test the assumption that an inhomogeneous distribution of conformational substates results in inhomogeneously broadened spectra. CO was slowly photolyzed at different wavelengths in the Soret band at 10 K. Both the Soret band and the CO-stretch band A1, centered at 1,945 cm-1, shift during photolysis, demonstrating that different wavelengths …

Isoprenylation Is Required For The Processing Of The Lamin A Precursor, Michael Sinensky, L. A. Beck, T. J. Hosick

Michael Sinensky

The nuclear lamina proteins, prelamin A, lamin B, and a 70-kD lamina-associated protein, are posttranslationally modified by a metabolite derived from mevalonate. This modification can be inhibited by treatment with (3-R,S)-3-fluoromevalonate, demonstrating that it is isoprenoid in nature. We have examined the association between isoprenoid metabolism and processing of the lamin A precursor in human and hamster cells. Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevinolin (lovastatin) specifically depletes endogenous isoprenoid pools and inhibits the conversion of prelamin A to lamin A. Prelamin A processing is also blocked by mevalonate starvation of Mev-1, a CHO cell line auxotrophic for mevalonate. …