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Physical Sciences and Mathematics Commons™
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Articles 1 - 6 of 6
Full-Text Articles in Physical Sciences and Mathematics
195 - Targeting Telomeric And C-Myc G4 Dna As An Anticancer Approach, Alexander Michaels, Sameela Haidari, Courtney Fetzer
195 - Targeting Telomeric And C-Myc G4 Dna As An Anticancer Approach, Alexander Michaels, Sameela Haidari, Courtney Fetzer
GREAT Day Posters
G-quadruplex (G4) DNA are non-canonical higher order DNA structures formed from guanine rich sequences, made up of stacked G-tetrads stabilized by non-Watson-Crick (Hoogsteen) base pairing and K+ ions. Early interests in G4 DNA were spurred on by the revelation that G4 was formed in telomeric DNA sequences at the end of our chromosomes. This was particularly promising given that G4 structures formed in telomeric DNA were also found to inhibit an enzyme known as telomerase, which is overexpressed (>90%) in cancer cells. Cancer cells require telomerase activity for survival and "immortality", therefore stabilization of telomeric G4 can inhibit …
263 - Housing And Integrating Bats Into The Suny Geneseo Campus Ecosystem., Hailey Cullen, Gabrielle Joseph
263 - Housing And Integrating Bats Into The Suny Geneseo Campus Ecosystem., Hailey Cullen, Gabrielle Joseph
GREAT Day Posters
This presentation centers on research conducted on building a sustainable prototype design of a bat box. We focused on configuring the implementation of bat boxes around the SUNY Geneseo campus as well as the optimal materials to use in the building of this prototype. The primary species targeted in our research and design development is the big brown bat.
219 - Developing A Portable System Of Environmental Dna (Edna) Surveillance To Monitor Fish Population Dynamics And Detect Invasive Species In Conesus Lake And The Philippine Seas, Karina Mirza, Micah Ford, Morgan Comstock
219 - Developing A Portable System Of Environmental Dna (Edna) Surveillance To Monitor Fish Population Dynamics And Detect Invasive Species In Conesus Lake And The Philippine Seas, Karina Mirza, Micah Ford, Morgan Comstock
GREAT Day Posters
Climate change is an increasing threat to many ecosystems worldwide. Due to global warming, many species are under threat of extinction while others are forced into unusual patterns of migration. In the Philippines, the fish Round Scad is a cheap source of protein in the diet of common citizens. Alarmingly, it is rapidly declining in both population and body size. In this project, we aim to develop a cheap, rapid, and sensitive method of monitoring the population dynamics of this fish in the wild. Recently, a new method called environmental DNA (eDNA) metabarcoding has been developed as a cost-effective way …
187 - Modeling The Dynamics Of Chromosomal Alteration Progression In Cervical Cancer: A Computational Model, Mike Mascitti
187 - Modeling The Dynamics Of Chromosomal Alteration Progression In Cervical Cancer: A Computational Model, Mike Mascitti
GREAT Day Posters
Cervical cancer is a complex disease characterized by unpredictable genetic alterations of cells. Computational modeling may be applied to simulate the growth and behavior of cervical cancer within a tissue and the progression of the disease throughout the body. In our computational model, individual cells have the ability to transform behavior between the following states: healthy, precursor lesion (CN1, CN2, CN3), and cancer. Each cell state has a different mutation rate, reproductive rate, and cell life span. Our model simulates the transformation of cells into these different states. The data from our computational model shows the day-to-day growth of cancer …
221 - Angkorian Temples In Mainland Southeast Asia: Cambodia, Laos, Thailand & Vietnam 9th - 15th Century, Sophuth Phon
221 - Angkorian Temples In Mainland Southeast Asia: Cambodia, Laos, Thailand & Vietnam 9th - 15th Century, Sophuth Phon
GREAT Day Posters
The Angkorian Era of the Khmer Empire (9th - 15th AD) is notable for its construction of numerous temples of high architectural heritage value, yet those temples have not been studied in depth. The spatial distribution of those temples, and their various historical characteristics, are also yet to be analyzed or mapped out. The purpose of this project is to spatially map the temple and discern if locations correlate to the region’s geography. This project compiled primary data on 70 major Angkorian temples in mainland Southeast Asia using various sources but primarily Google Earth Pro and Humanitarian Data Exchange (HDX). …
339 - Snowvember 2.0: Mapping Lake-Effect Snowfall In The Buffalo, New York Area During The November 2022 Extreme Snowfall Event, Gabrielle Puente
339 - Snowvember 2.0: Mapping Lake-Effect Snowfall In The Buffalo, New York Area During The November 2022 Extreme Snowfall Event, Gabrielle Puente
GREAT Day Posters
The City of Buffalo, New York is located in western New York State near two Great Lakes: Lake Ontario to the north, and Lake Erie to the west. The Great Lakes region that includes Buffalo experiences a weather phenomenon known as lake-effect snow, where surface buoyant instability and upward moisture movement from the Great Lakes can cause extreme snowfall in localized bands. The purpose of this project is to analyze the total amount of snowfall that occurred on a specific lake-effect snowfall even in November 2022, termed "Snowvember 2.0" (or November 2022 Great Lakes Winter Storm.) Snowfall data was obtained …