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Physical Sciences and Mathematics Commons™
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Full-Text Articles in Physical Sciences and Mathematics
Deep Learning, Medical Physics And Cargo Cult Science., Miguel Romero Phd, Gilmer Valdes Phd, Timothy Solberg Phd, Yannet Interian Phd
Deep Learning, Medical Physics And Cargo Cult Science., Miguel Romero Phd, Gilmer Valdes Phd, Timothy Solberg Phd, Yannet Interian Phd
Creative Activity and Research Day - CARD
Deep learning algorithms have become widely popular, with considerable success in fields where datasets have hundreds of thousands or million points. As deep learning is increasingly applied to the fields of medical physics and radiation oncology, a reasonable question follows: are these techniques the best approach, given the unique conditions in our field? In this study, we investigate the dependence of dataset size on the performance of deep learning algorithms compared with more traditional radiomics-based methods.
Data Analytics Pipeline For Rna Structure Analysis Via Shape, Quinn Nelson
Data Analytics Pipeline For Rna Structure Analysis Via Shape, Quinn Nelson
UNO Student Research and Creative Activity Fair
Coxsackievirus B3 (CVB3) is a cardiovirulent enterovirus from the family Picornaviridae. The RNA genome houses an internal ribosome entry site (IRES) in the 5’ untranslated region (5’UTR) that enables cap-independent translation. Ample evidence suggests that the structure of the 5’UTR is a critical element for virulence. We probe RNA structure in solution using base-specific modifying agents such as dimethyl sulfate as well as backbone targeting agents such as N-methylisatoic anhydride used in Selective 2’-Hydroxyl Acylation Analyzed by Primer Extension (SHAPE). We have developed a pipeline that merges and evaluates base-specific and SHAPE data together with statistical analyses that provides confidence …