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Full-Text Articles in Physical Sciences and Mathematics
Combination Nanomedicines For Cancer Therapy, Noureen Siraj
Combination Nanomedicines For Cancer Therapy, Noureen Siraj
Arkansas Women in STEM Conference
Nanomedicines derived from combination ionic nanomaterials (INMs) offer synergistic therapy for effective treatment of cancer. This approach addresses the limitations of conventional treatment options and offers active targeting of tumors due to EPR effect
Carrier-Free Chemo-Ptt/Pdt Ionic Nanomaterials For Combination Cancer Therapy, Samantha Macchi
Carrier-Free Chemo-Ptt/Pdt Ionic Nanomaterials For Combination Cancer Therapy, Samantha Macchi
Arkansas Women in STEM Conference
Herein, we describe a carrier-free combination nanodrug for treatment of cancer. In this work, we combined a photothermal compound and a chemotherapeutic drug using ionic liquid chemistry. We utilized a facile, one-step metathesis approach to replace the counter cation of a near infra-red (NIR) dye (photothermal agent) with a chemotherapeutic cation to synthesize an ionic material-based combination cancer therapy drug to deliver multiple mechanisms simultaneously. The nanodrugs were developed by using a reprecipitation method. The detailed photophysical properties of this new combination therapy molecule was investigated in ethanol solution as well as in nanoparticles forms in aqueous media. The singlet …