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Articles 1 - 7 of 7
Full-Text Articles in Physical Sciences and Mathematics
Ssrn As An Initial Revolution In Academic Knowledge Aggregation And Dissemination, David Bray, Sascha Vitzthum, Benn Konsynski
Ssrn As An Initial Revolution In Academic Knowledge Aggregation And Dissemination, David Bray, Sascha Vitzthum, Benn Konsynski
Sascha Vitzthum
Within this paper we consider our results of using the Social Science Research Network (SSRN) over a period of 18 months to distribute our working papers to the research community. Our experiences have been quite positive, with SSRN serving as a platform both to inform our colleagues about our research as well as inform us about related research (through email and telephoned conversations of colleagues who discovered our paper on SSRN). We then discuss potential future directions for SSRN to consider, and how SSRN might well represent an initial revolution in 21st century academic knowledge aggregation and dissemination. Our paper …
Towards Self-Organizing, Smart Business Networks: Let’S Create ‘Life’ From Inert Information, David Bray, Benn Konsynski
Towards Self-Organizing, Smart Business Networks: Let’S Create ‘Life’ From Inert Information, David Bray, Benn Konsynski
David A. Bray
We review three different theories that can inform how researchers can determine the performance of smart business networks, to include: (1) the Theory of Evolution, (2) the Knowledge-Based Theory of the Firm, and (3) research insights into computers and cognition. We suggest that each of these theories demonstrate that to be generally perceived as smart, an organism needs to be self-organizing, communicative, and tool-making. Consequentially, to determine the performance of a smart business network, we suggest that researchers need to determine the degree to which it is self-organizing, communicative, and tool-making. We then relate these findings to the Internet and …
Effect Of Statins On Serum Apolipoprotein J And Paraoxonase-1 Levels In Patients With Ischemic Heart Disease Undergoing Coronary Angiography, Mark Wilson, Dimitri Mikhailidis, Maria Poulakou, Despina Perrea, Kosmas Paraskevas, Dimitrios Iliopoulos, Serafim Tsitsilonis, Ioannis Vlachos, Sonia-Athena Karabina
Effect Of Statins On Serum Apolipoprotein J And Paraoxonase-1 Levels In Patients With Ischemic Heart Disease Undergoing Coronary Angiography, Mark Wilson, Dimitri Mikhailidis, Maria Poulakou, Despina Perrea, Kosmas Paraskevas, Dimitrios Iliopoulos, Serafim Tsitsilonis, Ioannis Vlachos, Sonia-Athena Karabina
Mark R Wilson
No abstract provided.
Carotenoid Intake Does Not Mediate A Relationship Between Reactive Oxygen Species And Bright Colouration: Experimental Test In A Lizard, Mark Wilson, Mats Olsson, Tobias Uller, Caroline Isaksson, Beth Mott
Carotenoid Intake Does Not Mediate A Relationship Between Reactive Oxygen Species And Bright Colouration: Experimental Test In A Lizard, Mark Wilson, Mats Olsson, Tobias Uller, Caroline Isaksson, Beth Mott
Mark R Wilson
No abstract provided.
Free Radicals Run In Lizard Families, Mark Wilson, Mats Olsson, Tobias Uller, Caroline Isaksson, Beth Mott, Mo Healey, Wanger Thomas
Free Radicals Run In Lizard Families, Mark Wilson, Mats Olsson, Tobias Uller, Caroline Isaksson, Beth Mott, Mo Healey, Wanger Thomas
Mark R Wilson
No abstract provided.
Rounds, Levels, And Waves: The Early Evolution Of Gameplay Segmentation, Jose Zagal, Clara Fernandez-Vara, Michael Mateas
Rounds, Levels, And Waves: The Early Evolution Of Gameplay Segmentation, Jose Zagal, Clara Fernandez-Vara, Michael Mateas
Jose P Zagal
This article explores the early evolution of the structure and management of gameplay in videogames. We introduce the notion of gameplay segmentation to capture the role that design elements like level, boss, and wave play in videogames, and identify three modes of segmentation. Temporal segmentation limits, synchronizes and/or coordinates player activity over time. Spatial segmentation breaks the game’s virtual space into sub-locations. Challenge segmentation presents the player with a sequence of self-contained challenges. We describe each mode, and additional sub-modes, by analyzing vintage arcade games. Our analyses illustrate how these games represent a “primordial soup” in which many current game …
Protease Activation Of A2-Macroglobulin Modulates A Chaperone-Like Action With Broad Specificity, Katie French, Justin Yerbury, Mark Wilson
Protease Activation Of A2-Macroglobulin Modulates A Chaperone-Like Action With Broad Specificity, Katie French, Justin Yerbury, Mark Wilson
Mark R Wilson
α2-Macroglobulin (α2M) is a major human blood glycoprotein best known for its ability to inhibit a broad spectrum of proteases by a unique trapping method. This action induces an “activated” conformation of α2M with an exposed binding site for the low density lipoprotein receptor, facilitating clearance of α2M-protease complexes from the body. This report establishes that protease activation also modulates a potent chaperone-like action of α2M which has broad specificity for proteins partly unfolded as a result of heat or oxidative stress. Protease-mediated activation of α2M abolishes its chaperone-like activity. However, native α2M is able to form soluble complexes with …