Physical Sciences and Mathematics Commons^™

Semi-Supervised Regression With Generative Adversarial Networks Using Minimal Labeled Data, Greg Olmschenk

Dissertations, Theses, and Capstone Projects

This work studies the generalization of semi-supervised generative adversarial networks (GANs) to regression tasks. A novel feature layer contrasting optimization function, in conjunction with a feature matching optimization, allows the adversarial network to learn from unannotated data and thereby reduce the number of labels required to train a predictive network. An analysis of simulated training conditions is performed to explore the capabilities and limitations of the method. In concert with the semi-supervised regression GANs, an improved label topology and upsampling technique for multi-target regression tasks are shown to reduce data requirements. Improvements are demonstrated on a wide variety of vision …

Statistical Machine Learning Methods For Mining Spatial And Temporal Data, Fei Tan

Dissertations

Spatial and temporal dependencies are ubiquitous properties of data in numerous domains. The popularity of spatial and temporal data mining has thus grown with the increasing prevalence of massive data. The presence of spatial and temporal attributes not only provides complementary useful perspectives, but also poses new challenges to the representation and integration into the learning procedure. In this dissertation, the involved spatial and temporal dependencies are explored with three genres: sample-wise, feature-wise, and target-wise. A family of novel methodologies is developed accordingly for the dependency representation in respective scenarios.

First, dependencies among discrete, continuous and repeated observations are studied …

Applying Machine Learning Algorithms For The Analysis Of Biological Sequences And Medical Records, Shaopeng Gu

Electronic Theses and Dissertations

The modern sequencing technology revolutionizes the genomic research and triggers explosive growth of DNA, RNA, and protein sequences. How to infer the structure and function from biological sequences is a fundamentally important task in genomics and proteomics fields. With the development of statistical and machine learning methods, an integrated and user-friendly tool containing the state-of-the-art data mining methods are needed. Here, we propose SeqFea-Learn, a comprehensive Python pipeline that integrating multiple steps: feature extraction, dimensionality reduction, feature selection, predicting model constructions based on machine learning and deep learning approaches to analyze sequences. We used enhancers, RNA N6- methyladenosine sites and …