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Roc Surfaces In The Presence Of Verification Bias, Yueh-Yun Chi, Xiao-Hua (Andrew) Zhou
Roc Surfaces In The Presence Of Verification Bias, Yueh-Yun Chi, Xiao-Hua (Andrew) Zhou
UW Biostatistics Working Paper Series
In diagnostic medicine, the Receiver Operating Characteristic (ROC) surface is one of the established tools for assessing the accuracy of a diagnostic test in discriminating three disease states, and the volume under the ROC surface has served as a summary index for diagnostic accuracy. In practice, the selection for definitive disease examination may be based on initial test measurements, and induces verification bias in the assessment. We propose here a nonparametric likelihood-based approach to construct the empirical ROC surface in the presence of differential verification, and to estimate the volume under the ROC surface. Estimators of the standard deviation are …