Physical Sciences and Mathematics Commons^™

Confidence Interval Estimation For Continuous Outcomes In Cluster Randomization Trials, Julia Taleban

Electronic Thesis and Dissertation Repository

Cluster randomization trials are experiments where intact social units (e.g. hospitals, schools, communities, and families) are randomized to the arms of the trial rather than individuals. The popularity of this design among health researchers is partially due to reduced contamination of treatment effects and convenience. However, the advantages of cluster randomization trials come with a price. Due to the dependence of individuals within a cluster, cluster randomization trials suffer reduced statistical efficiency and often require a complex analysis of study outcomes.

The primary purpose of this thesis is to propose new confidence intervals for effect measures commonly of interest for …