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Full-Text Articles in Physical Sciences and Mathematics
Using The Inverse Transform To Specify Contrasts In Regression And Latent Curve Structural Equation Models, Thomas N. Templin
Using The Inverse Transform To Specify Contrasts In Regression And Latent Curve Structural Equation Models, Thomas N. Templin
Nursing Faculty Research Publications
A simple yet general method for specifying contrasts to test hypotheses in regression and latent curve structural equation models is presented. The traditional qualitative variable coding schemes used in multiple regression (e.g., dummy coding) have a more general formulation. Five matrices are involved: The coding scheme, A. The matrix which gives the distribution and ordering of cases, W; WA = X; X is the design matrix. The contrast coefficient matrix C; and C-1 = A. In practice, only C, C-1, and A are necessary because the statistical software generates the design matrix. This method has great generality …
Singular Ergodic Control For Multidimensional Gaussian-Poisson Processes, J. L. Menaldi, M. Robin
Singular Ergodic Control For Multidimensional Gaussian-Poisson Processes, J. L. Menaldi, M. Robin
Mathematics Faculty Research Publications
Singular control for multidimensional Gaussian-Poisson processes with a long-run (or ergodic) and a discounted criteria are discussed. The dynamic programming yields the corresponding Hamilton-Jacobi-Bellman equations, which are discussed. Full details on the proofs and further extensions are left for coming works.
Initiation And Continuation Of Randomized Trials After The Publication Of A Trial Stopped Early For Benefit Asking The Same Study Question: Stopit-3 Study Design, Gabriela J. Prutsky, Juan Domecq, Patricia J. Erwin, Matthias Briel, Victor M. Montori, Elie A. Akl, Joerg J. Meerpohl, Dirk Bassler, Stefan Schandelmaier, Stephen D. Walter, Qi Zhou, Pablo Coello, Lorenzo Moja, Martin Walter, Kristian Thorlund, Paul Glasziou, Regina Kunz, Ignacio Ferreira-Gonzalez, Jason Busse, Xin Sun, Annette Kristiansen, Benjamin Kasenda, Osama Qasim-Agha, Gennaro Pagano, Hector Pardo-Hernandez, Gerard Urrutia, Mohammad Murad, Gordon Guyatt
Initiation And Continuation Of Randomized Trials After The Publication Of A Trial Stopped Early For Benefit Asking The Same Study Question: Stopit-3 Study Design, Gabriela J. Prutsky, Juan Domecq, Patricia J. Erwin, Matthias Briel, Victor M. Montori, Elie A. Akl, Joerg J. Meerpohl, Dirk Bassler, Stefan Schandelmaier, Stephen D. Walter, Qi Zhou, Pablo Coello, Lorenzo Moja, Martin Walter, Kristian Thorlund, Paul Glasziou, Regina Kunz, Ignacio Ferreira-Gonzalez, Jason Busse, Xin Sun, Annette Kristiansen, Benjamin Kasenda, Osama Qasim-Agha, Gennaro Pagano, Hector Pardo-Hernandez, Gerard Urrutia, Mohammad Murad, Gordon Guyatt
Wayne State University Associated BioMed Central Scholarship
Abstract
Background
Randomized control trials (RCTs) stopped early for benefit (truncated RCTs) are increasingly common and, on average, overestimate the relative magnitude of benefit by approximately 30%. Investigators stop trials early when they consider it is no longer ethical to enroll patients in a control group. The goal of this systematic review is to determine how investigators of ongoing or planned RCTs respond to the publication of a truncated RCT addressing a similar question.
Methods/design
We will conduct systematic reviews to update the searches of 210 truncated RCTs to identify similar trials ongoing at the time of publication, or started …