Physical Sciences and Mathematics Commons^™

Choosing The Cut Point For A Restricted Mean In Survival Analysis, A Data Driven Method, Emily H. Sheldon

Theses and Dissertations

Survival Analysis generally uses the median survival time as a common summary statistic. While the median possesses the desirable characteristic of being unbiased, there are times when it is not the best statistic to describe the data at hand. Royston and Parmar (2011) provide an argument that the restricted mean survival time should be the summary statistic used when the proportional hazards assumption is in doubt. Work in Restricted Means dates back to 1949 when J.O. Irwin developed a calculation for the standard error of the restricted mean using Greenwood’s formula. Since then the development of the restricted mean has …