Physical Sciences and Mathematics Commons^™

Efficiency Of An Unbalanced Design In Collecting Time To Event Data With Interval Censoring, Peiyao Cheng

USF Tampa Graduate Theses and Dissertations

In longitudinal studies, the exact timing of an event often cannot be observed, and is usually detected at a subsequent visit, which is called interval censoring. Spacing of the visits is important when designing study with interval censored data. In a typical longitudinal study, the spacing of visits is usually the same across all subjects (balanced design). In this dissertation, I propose an unbalanced design: subjects at baseline are divided into a high risk group and a low risk group based on a risk factor, and the subjects in the high risk group are followed more frequently than those in …