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Topics In Group Testing With Multiple Infections, Peijie Hou
Topics In Group Testing With Multiple Infections, Peijie Hou
Theses and Dissertations
Group testing, dating back to the early 1940s, was first proposed to screen for syphilis among US inductees during World War II (Dorfman, 1943). Since then, the benefits of reducing testing costs by employing group testing have been demonstrated in many areas, such as drug discovery, genetics, and infectious disease testing. Traditionally, statistical research in group testing has largely been motivated by applications involving a single infection. With the recent development of multiplex assays that can diagnose multiple infections simultaneously, generalizing the existing group testing literature to incorporate multiple infections is a natural and necessary next step. This dissertation consists …
Modern Estimation Problems In Group Testing, Md Shamim Sarker
Modern Estimation Problems In Group Testing, Md Shamim Sarker
Theses and Dissertations
In the simplest form of group testing, pools are formed by compositing a fixed number of individual specimens (e.g., blood, urine, swab, etc.) and then the pools are tested for a binary characteristic, such as presence or absence of a disease. Group testing is commonly used to screen for a variety of sexually transmitted diseases in epidemiological applications where the main goal is to increase testing efficiency. In this dissertation, we study three estimation problems that are motivated by real-life applications. We propose new methods to model group testing data for both single and multiple infections. In the first problem, …