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Estimation Of The Three Key Parameters And The Lead Time Distribution In Lung Cancer Screening., Ruiqi Liu

Electronic Theses and Dissertations

This dissertation contains three research projects on cancer screening probability modeling. Cancer screening is the primary technique for early detection. The goal of screening is to catch the disease early before clinical symptoms appear. In these projects, the three key parameters and lead time distribution were estimated to provide a statistical point of view on the effectiveness of cancer screening programs. In the first project, cancer screening probability model was used to analyze the computed tomography (CT) scan group in the National Lung Screening Trial (NLST) data. Three key parameters were estimated using Bayesian approach and Markov Chain Monte Carlo …