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Full-Text Articles in Physical Sciences and Mathematics

Bayesian Model For Detection Of Outliers In Linear Regression With Application To Longitudinal Data, Zahraa Al-Sharea Dec 2017

Bayesian Model For Detection Of Outliers In Linear Regression With Application To Longitudinal Data, Zahraa Al-Sharea

Graduate Theses and Dissertations

Outlier detection is one of the most important challenges with many present-day applications. Outliers can occur due to uncertainty in data generating mechanisms or due to an error in data recording/processing. Outliers can drastically change the study's results and make predictions less reliable. Detecting outliers in longitudinal studies is quite challenging because this kind of study is working with observations that change over time. Therefore, the same subject can produce an outlier at one point in time produce regular observations at all other time points. A Bayesian hierarchical modeling assigns parameters that can quantify whether each observation is an outlier …


Identifying Three-Way Gene Interactions From Microarray Data Using Kolmogorov-Smirnov And Cross-Match Tests, Shubhashree Khadka Aug 2017

Identifying Three-Way Gene Interactions From Microarray Data Using Kolmogorov-Smirnov And Cross-Match Tests, Shubhashree Khadka

Graduate Theses and Dissertations

Human gene network is much more complex than just pairwise interaction among the genes. Zhang et al. [6] extracted microarray data from International Genomics Consortium (IGC), and presented the detection of three-way gene interactions in their paper using Fisher’s z-transformation test. Three-way gene interactions are closer than pairwise correlations in representing the complex gene structures. Additionally, it was more tractable than assessing four or more gene interactions. In this paper, we are simulating different models where Fisher’s test might not be as effective. Zhang et al.’s approach utilized Pearson’s correlation coefficients and involved detection of linear interactions only. Since gene …


Genomic And Physiological Approaches To Improve Drought Tolerance In Soybean, Avjinder Kaler Aug 2017

Genomic And Physiological Approaches To Improve Drought Tolerance In Soybean, Avjinder Kaler

Graduate Theses and Dissertations

Drought stress is a major global constraint for crop production, and improving crop tolerance to drought is of critical importance. Direct selection of drought tolerance among genotypes for yield is limited because of low heritability, polygenic control, epistasis effects, and genotype by environment interactions. Crop physiology can play a major role for improving drought tolerance through the identification of traits associated with drought tolerance that can be used as indirect selection criteria in a breeding program. Carbon isotope ratio (δ13C, associated with water use efficiency), oxygen isotope ratio (δ18O, associated with transpiration), canopy temperature (CT), canopy wilting, and canopy coverage …


A Linear-Linear Growth Model With Individual Change Point And Its Application To Ecls-K Data, Ping Zhang Aug 2017

A Linear-Linear Growth Model With Individual Change Point And Its Application To Ecls-K Data, Ping Zhang

Graduate Theses and Dissertations

The latent growth curve model with piecewise functions is a useful analytics tool to investigate the growth trajectory consisted of distinct phases of development in observed variables. An interesting feature of the growth trajectory is the time point that the trajectory changes from one phase to another one. In this thesis, we propose a simple computational pipeline to locate the change point under the linear-linear piecewise model and apply it to the longitudinal study of reading and math ability in early childhood (from kindergarten to eighth grade). In the first step, we conduct the hypothesis testing to filter out the …


A Bayesian Variable Selection Method With Applications To Spatial Data, Xiahan Tang May 2017

A Bayesian Variable Selection Method With Applications To Spatial Data, Xiahan Tang

Graduate Theses and Dissertations

This thesis first describes the general idea behind Bayes Inference, various sampling methods based on Bayes theorem and many examples. Then a Bayes approach to model selection, called Stochastic Search Variable Selection (SSVS) is discussed. It was originally proposed by George and McCulloch (1993). In a normal regression model where the number of covariates is large, only a small subset tend to be significant most of the times. This Bayes procedure specifies a mixture prior for each of the unknown regression coefficient, the mixture prior was originally proposed by Geweke (1996). This mixture prior will be updated as data becomes …