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Physical Sciences and Mathematics Commons™
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Articles 1 - 2 of 2
Full-Text Articles in Physical Sciences and Mathematics
A Nonlinear Filter For Markov Chains And Its Effect On Diffusion Maps, Stefan Steinerberger
A Nonlinear Filter For Markov Chains And Its Effect On Diffusion Maps, Stefan Steinerberger
Yale Day of Data
Diffusion maps are a modern mathematical tool that helps to find structure in large data sets - we present a new filtering technique that is based on the assumption that errors in the data are intrinsically random to isolate and filter errors and thus boost the efficiency of diffusion maps. Applications include data sets from medicine (the Cleveland Heart Disease Data set and the Wisconsin Breast Cancer Data set) and engineering (the Ionosphere data set).
K-Mer Analysis On Developmental And Housekeeping Enhancer Peaks, Yunsi Yang, Anurag Sethi, Mark Gerstein
K-Mer Analysis On Developmental And Housekeeping Enhancer Peaks, Yunsi Yang, Anurag Sethi, Mark Gerstein
Yale Day of Data
The regulation of gene expression involves interaction between transcriptional enhancers and core promoters. However, the separation between developmental and housekeeping gene regulation remains unknown. Here, we present a method to detect if different core promoters exhibit specificity to certain enhancers within massively parallel assays for enhancer detection. We use k-mers of various length (3-8bp) as sequence features and compare k-mer frequencies between developmental and housekeeping enhancers. This method shows promoter specificity of enhancers in D. melanogaster.