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Physical Sciences and Mathematics Commons

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Statistics and Probability

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Purdue University

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2019

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Full-Text Articles in Physical Sciences and Mathematics

Twitter And Disasters: A Social Resilience Fingerprint, Benjamin A. Rachunok, Jackson B. Bennett, Roshanak Nateghi May 2019

Twitter And Disasters: A Social Resilience Fingerprint, Benjamin A. Rachunok, Jackson B. Bennett, Roshanak Nateghi

Purdue University Libraries Open Access Publishing Fund

Understanding the resilience of a community facing a crisis event is critical to improving its adaptive capacity. Community resilience has been conceptualized as a function of the resilience of components of a community such as ecological, infrastructure, economic, and social systems, etc. In this paper, we introduce the concept of a “resilience fingerprint” and propose a multi-dimensional method for analyzing components of community resilience by leveraging existing definitions of community resilience with data from the social network Twitter. Twitter data from 14 events are analyzed and their resulting resilience fingerprints computed. We compare the fingerprints between events and show that …


Inferring Gene Regulatory Networks From A Population Of Yeast Segregants, Chen Chen, Dabao Zhang, Tony R. Hazbun, Min Zhang Feb 2019

Inferring Gene Regulatory Networks From A Population Of Yeast Segregants, Chen Chen, Dabao Zhang, Tony R. Hazbun, Min Zhang

Purdue University Libraries Open Access Publishing Fund

Constructing gene regulatory networks is crucial to unraveling the genetic architecture of complex traits and to understanding the mechanisms of diseases. On the basis of gene expression and single nucleotide polymorphism data in the yeast, Saccharomyces cerevisiae, we constructed gene regulatory networks using a two-stage penalized least squares method. A large system of structural equations via optimal prediction of a set of surrogate variables was established at the first stage, followed by consistent selection of regulatory effects at the second stage. Using this approach, we identified subnetworks that were enriched in gene ontology categories, revealing directional regulatory mechanisms controlling …