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Physical Sciences and Mathematics Commons

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Social and Behavioral Sciences

Selected Works

Professor Nick E Dixon

2013

Tus

Articles 1 - 2 of 2

Full-Text Articles in Physical Sciences and Mathematics

Ultrasensitive Detection Of Antibodies Using A New Tus-Ter-Lock Immunopcr System, Isabelle Morin, Nicholas E. Dixon, Patrick M. Schaeffer Jul 2013

Ultrasensitive Detection Of Antibodies Using A New Tus-Ter-Lock Immunopcr System, Isabelle Morin, Nicholas E. Dixon, Patrick M. Schaeffer

Professor Nick E Dixon

A system consisting of a protein LG coated surface for the capture of mammalian antibodies (target), and an antigen fused to Tus and stoichiometrically linked to a DNA template via the Tus-Ter-lock sequence allowed the ultrasensitive detection of 5.5 attomol of target by real-time immunoPCR in complex media. © The Royal Society of Chemistry 2010.


Site-Specific Covalent Attachment Of Dna To Proteins Using A Photoactivatable Tus-Ter Complex, Dahdah B. Dahdah, Isabelle Morin, Morgane Moreau, Nicholas E. Dixon, Patrick M. Schaeffer Jul 2013

Site-Specific Covalent Attachment Of Dna To Proteins Using A Photoactivatable Tus-Ter Complex, Dahdah B. Dahdah, Isabelle Morin, Morgane Moreau, Nicholas E. Dixon, Patrick M. Schaeffer

Professor Nick E Dixon

Investigations into the photocrosslinking kinetics of the protein Tus with various bromodeoxyuridine-substituted Ter DNA variants highlight the potential use of this complex as a photoactivatable connector between proteins of interest and specific DNA sequences.