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Physical Sciences and Mathematics Commons™

Open Access. Powered by Scholars. Published by Universities.®

Physics

University of Louisville

2018

Articles 1 - 6 of 6

Full-Text Articles in Physical Sciences and Mathematics

Innate Immunity, The Hepatic Extracellular Matrix, And Liver Injury: Mathematical Modeling Of Metastatic Potential And Tumor Development In Alcoholic Liver Disease., Shanice V. Hudson Dec 2018

Innate Immunity, The Hepatic Extracellular Matrix, And Liver Injury: Mathematical Modeling Of Metastatic Potential And Tumor Development In Alcoholic Liver Disease., Shanice V. Hudson

Electronic Theses and Dissertations

The overarching goals of the current work are to fill key gaps in the current understanding of alcohol consumption and the risk of metastasis to the liver. Considering the evidence this research group has compiled confirming that the hepatic matrisome responds dynamically to injury, an altered extracellular matrix (ECM) profile appears to be a key feature of pre-fibrotic inflammatory injury in the liver. This group has demonstrated that the hepatic ECM responds dynamically to alcohol exposure, in particular, sensitizing the liver to LPS-induced inflammatory damage. Although the study of alcohol in its role as a contributing factor to oncogenesis and …

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Computational Prediction, Characterization, And Methodology Development For Two-Dimensional Nanostructures: Phosphorene And Phosphide Binary Compounds., Congyan Zhang Dec 2018

Computational Prediction, Characterization, And Methodology Development For Two-Dimensional Nanostructures: Phosphorene And Phosphide Binary Compounds., Congyan Zhang

Electronic Theses and Dissertations

In this thesis, a comprehensive computational simulation was carried out for predicting, characterizing, and applications of two-dimensional (2D) materials. The newly discovered GaP and InP layers were selected as an example to demonstrate how to explore new 2D materials using computational simulations. The performance of phosphorene as the anode material of Lithium-ion battery was discussed as the example of the application of 2D material. Furthermore, the semi-empirical Hamiltonian for phosphorous and lithium elements have been developed for our future work on the application of phosphorus and lithium-based systems. The novel 2D materials of GaP and InP binary compounds were found …

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Plasma Based Synthesis And Surface Modification Of Graphene., Rong Zhao Aug 2018

Plasma Based Synthesis And Surface Modification Of Graphene., Rong Zhao

Electronic Theses and Dissertations

Graphene, an atom thick layer of carbon, has attracted intense scientific interest due to its exceptional electrical, mechanical and chemical properties. Especially, it provides a perfect platform to explore the unique electronic properties in absolute two-dimension. Pristine graphene possesses zero band gap and weakens its competitiveness in the field of semiconductors. In order to induce a band gap and control its semiconducting properties, functionalization and doping are two of the most feasible methods. In the context of functionalization, large area monolayer graphene synthesized by chemical vapor deposition was subjected to controlled and sequential fluorination using radio frequency plasma while monitoring …

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High Dynamic Range Optical Devices And Applications., Elijah Robert Jensen Aug 2018

High Dynamic Range Optical Devices And Applications., Elijah Robert Jensen

Electronic Theses and Dissertations

Much of what we know about fundamental physical law and the universe derives from observations and measurements using optical methods. The passive use of the electromagnetic spectrum can be the best way of studying physical phenomenon in general with minimal disturbance of the system in the process. While for many applications ambient visible light is sufficient, light outside of the visible range may convey more information. The signals of interest are also often a small fraction of the background, and their changes occur on time scales so quickly that they are visually imperceptible. This thesis reports techniques and technologies developed …

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Photonic Tools For Advanced Sensing And Imaging At The Nanoscale., Jafar Hamed Ghithan May 2018

Photonic Tools For Advanced Sensing And Imaging At The Nanoscale., Jafar Hamed Ghithan

Electronic Theses and Dissertations

This dissertation reports a novel bio-sensing strategy based on single-mode, electro-active, integrated optical waveguide (SM-EA-IOW) platforms. It also reports the development of a super-resolved far-field optical imaging tool to enable optical, electronic, and spectroelectrochemical investigations at the nanoscale. SM-EA-IOW platforms with its outstanding sensitivity for spectroelectrochemical interrogation was combined with a sandwich bioassay for the development of a novel immunosensing based strategy for label-free detection of infectious pathogens. The strategy begins with the functionalization of the electroactive waveguide surface with a capturing antibody aimed at a specific target analyte. Once the target analyte is bound to the photonic interface, it …

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Efficient Quantum Approximation : Examining The Efficiency Of Select Universal Gate Sets In Approximating 1-Qubit Quantum Gates., Brent A. Mode May 2018

Efficient Quantum Approximation : Examining The Efficiency Of Select Universal Gate Sets In Approximating 1-Qubit Quantum Gates., Brent A. Mode

College of Arts & Sciences Senior Honors Theses

Quantum computation is of current ubiquitous interest in physics, computer science, and the public interest. In the not-so-distant future, quantum computers will be relatively common pieces of research equipment. Eventually, one can expect an actively quantum computer to be a common feature of life. In this work, I study the approximation efficiency of several common universal quantum gate sets at short sequence lengths using an implementation of the Solovay-Kitaev algorithm. I begin by developing from almost nothing the relevant formal mathematics to rigorously describe what one means by the terms universal gate set and covering efficiency. I then describe some …

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