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Full-Text Articles in Physical Sciences and Mathematics
Partial Molecular Volumes Of Lipids And Cholesterol., Alexander Greenwood, Stephanie Tristram-Nagle, John Nagle
Partial Molecular Volumes Of Lipids And Cholesterol., Alexander Greenwood, Stephanie Tristram-Nagle, John Nagle
Prof. Stephanie Tristram-Nagle Ph.D.
Volumetric measurements are reported for fully hydrated lipid/cholesterol bilayer mixtures using the neutral flotation method. Apparent specific volume data were obtained with the lipids DOPC, POPC and DMPC at T=30 degrees Celsius, DPPC at 50 degrees Celsius, and brain sphingomyelin (BSM) at 45 and 24 degrees Celsius for mole fractions of cholesterol x from 0 to 0.5. Unlike previous cholesterol mixture studies, we converted our raw data to partial molecular volume V(L) of the lipid and V(C) of the cholesterol. The partial molecular volumes were constant for POPC and DOPC as x was varied, but had sharp breaks for the …
Structure Of Lipid Bilayers, John Nagle, Stephanie Tristram-Nagle
Structure Of Lipid Bilayers, John Nagle, Stephanie Tristram-Nagle
Prof. Stephanie Tristram-Nagle Ph.D.
The quantitative experimental uncertainty in the structure of fully hydrated, biologically relevant, fluid (L(alpha)) phase lipid bilayers has been too large to provide a firm base for applications or for comparison with simulations. Many structural methods are reviewed including modern liquid crystallography of lipid bilayers that deals with the fully developed undulation fluctuations that occur in the L(alpha) phase. These fluctuations degrade the higher order diffraction data in a way that, if unrecognized, leads to erroneous conclusions regarding bilayer structure. Diffraction measurements at high instrumental resolution provide a measure of these fluctuations. In addition to providing better structural determination, this …
Molecular Structures Of Fluid Phase Phosphatidylglycerol Bilayers As Determined By Small Angle Neutron And X-Ray Scattering., Jianjun Pan, Frederick Heberle, Stephanie Tristram-Nagle, Michelle Szymanski, Mary Koepfinger, John Katsaras, Norbert Kucerka
Molecular Structures Of Fluid Phase Phosphatidylglycerol Bilayers As Determined By Small Angle Neutron And X-Ray Scattering., Jianjun Pan, Frederick Heberle, Stephanie Tristram-Nagle, Michelle Szymanski, Mary Koepfinger, John Katsaras, Norbert Kucerka
Prof. Stephanie Tristram-Nagle Ph.D.
We have determined the molecular structures of commonly used phosphatidylglycerols (PGs) in the commonly accepted biologically relevant fluid phase. This was done by simultaneously analyzing small angle neutron and X-ray scattering data, with the constraint of measured lipid volumes. We report the temperature dependence of bilayer parameters obtained using the one-dimensional scattering density profile model - which was derived from molecular dynamics simulations - including the area per lipid, the overall bilayer thickness, as well as other intrabilayer parameters (e.g., hydrocarbon thickness). Lipid areas are found to be larger than their phosphatidylcholine (PC) counterparts, a result likely due to repulsive …
Orientation Of Tie-Lines In The Phase Diagram Of Dopc/Dppc/Cholesterol Model Biomembranes., Pradeep Uppamoochikkal, Stephanie Tristram-Nagle, John Nagle
Orientation Of Tie-Lines In The Phase Diagram Of Dopc/Dppc/Cholesterol Model Biomembranes., Pradeep Uppamoochikkal, Stephanie Tristram-Nagle, John Nagle
Prof. Stephanie Tristram-Nagle Ph.D.
We report the direction of tie-lines of coexisting phases in a ternary diagram of DOPC/DPPC/cholesterol lipid bilayers, which has been a system of interest in the discussion of biological rafts. For coexisting Ld and Lo phases, we find that the orientation angle α of the tie-lines increases as the cholesterol concentration increases and it also increases as temperature increases from T = 15 °C to T = 30 °C. Results at lower cholesterol concentrations support the existence of a different two-phase coexistence region of Ld and So phases and the existence of a three-phase region separating the two two-phase regions. …
Volumetric Stability Of Lipid Bilayers., Kelsey Hallinen, Stephanie Tristram-Nagle, John Nagle
Volumetric Stability Of Lipid Bilayers., Kelsey Hallinen, Stephanie Tristram-Nagle, John Nagle
Prof. Stephanie Tristram-Nagle Ph.D.
In agreement with recent reports, a commercial densimeter has yielded a gradual decrease in lipid molecular volume of DPPC multilamellar vesicle dispersions in the gel phase upon repeated thermal cycling between 10 °C and 50 °C. The considerable size of this decrease would have significant implications for the physical chemistry of biomembranes. In contrast, neutral buoyancy measurements performed with similar thermal cycling indicate no gradual change in lipid volume in the gel phase at 20 °C. Remixing the lipid in the densimeter shows that the apparent volume decrease is an artifact. We conclude that gel phase DPPC bilayers exist in …
Temperature Dependence Of The Training Effect In Exchange Coupled Ferromagnetic Bilayers, Christian Binek, Srinivas Polisetty, Sarbeswar Sahoo
Temperature Dependence Of The Training Effect In Exchange Coupled Ferromagnetic Bilayers, Christian Binek, Srinivas Polisetty, Sarbeswar Sahoo
Christian Binek
The temperature dependence of the training effect is studied in an exchange coupled thin-film bilayer composed of a hard ferromagnetic pinning (CoPtCrB) layer in proximity of a soft ferromagnetic pinned (CoCr) layer. Interlayer exchange shifts the hysteresis loops of the soft layer along the magnetic-field axis. This shift is quantified by the bias field in far reaching analogy to the exchange bias field of conventional antiferromagnetic/ferromagnetic heterostructures. A ferromagnetic domain state induced in the hard layer experiences aging very similar to the training behavior of the antiferromagnetic domain state in conventional exchange bias systems. Training originates from changes in the …
Robust Isothermal Electric Control Of Exchange Bias At Room Temperature, Xi He, Yi Wang, Christian Binek, Peter Dowben
Robust Isothermal Electric Control Of Exchange Bias At Room Temperature, Xi He, Yi Wang, Christian Binek, Peter Dowben
Christian Binek
Voltage-controlled spin electronics is crucial for continued progress in information technology. It aims at reduced power consumption, increased integration density and enhanced functionality where non-volatile memory is combined with highspeed logical processing. Promising spintronic device concepts use the electric control of interface and surface magnetization. From the combination of magnetometry, spin-polarized photoemission spectroscopy, symmetry arguments and first-principles calculations, we show that the (0001) surface of magnetoelectric Cr2O3 has a roughness-insensitive, electrically switchable magnetization. Using a ferromagnetic Pd/Co multilayer deposited on the (0001) surface of a Cr2O3 single crystal, we achieve reversible, room-temperature isothermal switching of the exchange-bias field between positive …
Characterization Of An N2 Flowing Microwave Post-Discharge By Oes Spectroscopy And Determination Of Absolute Ground-State Nitrogen Atom Densities By Talif, Et. Es-Sebbar, Y. Benilan, A. Jolly, M-C. Gazeau
Characterization Of An N2 Flowing Microwave Post-Discharge By Oes Spectroscopy And Determination Of Absolute Ground-State Nitrogen Atom Densities By Talif, Et. Es-Sebbar, Y. Benilan, A. Jolly, M-C. Gazeau
Dr. Et-touhami Es-sebbar
A flowing microwave post-discharge source sustained at 2.45 GHz in pure nitrogen has been investigated by optical emission spectroscopy (OES) and two-photon absorption laser-induced fluorescence (TALIF) spectroscopy. Variations of the optical emission along the post-discharge (near, pink and late afterglow) have been studied and the gas temperature has been determined. TALIF spectroscopy has been used in the late afterglow to determine the absolute ground-state nitrogen atomic densities using krypton as a reference gas. Measurements show that the microwave flowing post-discharge is an efficient source of N (4S) atoms in late afterglow. In our experimental conditions, the maximum N (4S) density …
Improvement Of Ferroelectric Fatigue Endurance In Multiferroic (Ba(0.5)Sr(0.5))Tio(3)/(Bi(1.05)La(0.05))Feo(3)/(Ba(0.5)Sr(0.5))Tio(3) Sandwich Structures, Chew Khian Hooi, Miao J., Zhang B. P., Wang Y.
Improvement Of Ferroelectric Fatigue Endurance In Multiferroic (Ba(0.5)Sr(0.5))Tio(3)/(Bi(1.05)La(0.05))Feo(3)/(Ba(0.5)Sr(0.5))Tio(3) Sandwich Structures, Chew Khian Hooi, Miao J., Zhang B. P., Wang Y.
Chew Khian Hooi
We report the improved ferroelectric properties in dielectric/multiferroic/dielectric sandwich structures composed of Ba(0.5)Sr(0.5)TiO(3) (BST) and Bi(1.05)La(0.05)FeO(3) (BLF). Compared with the single BLF film, the trilayer structures exhibit a lower dielectric loss and weaker frequency dependence of dielectric properties. At room temperature, the remnant polarization and saturation polarization of the trilayer structures are 34.3 and 46.9 mu C/cm(2), respectively. More interestingly, the polarization of BST/BLF/BST trilayer exhibits a fatigue-free characteristic of up to 10(9) switching cycles. Applying Dawber's model, the concentration of oxygen vacancies and barrier energy of oxygen vacancies migration in BST/BLF/BST trilayer are calculated as 6.1x10(17) cm(-3) and 1.33 …