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Full-Text Articles in Physical Sciences and Mathematics

Toward Intuitive 3d Interactions In Virtual Reality: A Deep Learning- Based Dual-Hand Gesture Recognition Approach, Trudi Di Qi, Franceli L. Cibrian, Meghna Raswan, Tyler Kay, Hector M. Camarillo-Abad, Yuxin Wen May 2024

Toward Intuitive 3d Interactions In Virtual Reality: A Deep Learning- Based Dual-Hand Gesture Recognition Approach, Trudi Di Qi, Franceli L. Cibrian, Meghna Raswan, Tyler Kay, Hector M. Camarillo-Abad, Yuxin Wen

Engineering Faculty Articles and Research

Dual-hand gesture recognition is crucial for intuitive 3D interactions in virtual reality (VR), allowing the user to interact with virtual objects naturally through gestures using both handheld controllers. While deep learning and sensor-based technology have proven effective in recognizing single-hand gestures for 3D interactions, research on dual-hand gesture recognition for VR interactions is still underexplored. In this work, we introduce CWT-CNN-TCN, a novel deep learning model that combines a 2D Convolution Neural Network (CNN) with Continuous Wavelet Transformation (CWT) and a Temporal Convolution Network (TCN). This model can simultaneously extract features from the time-frequency domain and capture long-term dependencies using …


Exploring Binding Pockets In The Conformational States Of The Sars-Cov-2 Spike Trimers For The Screening Of Allosteric Inhibitors Using Molecular Simulations And Ensemble-Based Ligand Docking, Grace Gupta, Gennady M. Verkhivker May 2024

Exploring Binding Pockets In The Conformational States Of The Sars-Cov-2 Spike Trimers For The Screening Of Allosteric Inhibitors Using Molecular Simulations And Ensemble-Based Ligand Docking, Grace Gupta, Gennady M. Verkhivker

Mathematics, Physics, and Computer Science Faculty Articles and Research

Understanding mechanisms of allosteric regulation remains elusive for the SARS-CoV-2 spike protein, despite the increasing interest and effort in discovering allosteric inhibitors of the viral activity and interactions with the host receptor ACE2. The challenges of discovering allosteric modulators of the SARS-CoV-2 spike proteins are associated with the diversity of cryptic allosteric sites and complex molecular mechanisms that can be employed by allosteric ligands, including the alteration of the conformational equilibrium of spike protein and preferential stabilization of specific functional states. In the current study, we combine conformational dynamics analysis of distinct forms of the full-length spike protein trimers and …


Predicting Ffar4 Agonists Using Structure-Based Machine Learning Approach Based On Molecular Fingerprints, Zaid Anis Sherwani, Syeda Sumayya Tariq, Mamona Mushtaq, Ali Raza Siddiqui, Mohammad Nur-E-Alam, Aftab Ahmed, Zaheer Ul-Haq Apr 2024

Predicting Ffar4 Agonists Using Structure-Based Machine Learning Approach Based On Molecular Fingerprints, Zaid Anis Sherwani, Syeda Sumayya Tariq, Mamona Mushtaq, Ali Raza Siddiqui, Mohammad Nur-E-Alam, Aftab Ahmed, Zaheer Ul-Haq

Pharmacy Faculty Articles and Research

Free Fatty Acid Receptor 4 (FFAR4), a G-protein-coupled receptor, is responsible for triggering intracellular signaling pathways that regulate various physiological processes. FFAR4 agonists are associated with enhancing insulin release and mitigating the atherogenic, obesogenic, pro-carcinogenic, and pro-diabetogenic effects, normally associated with the free fatty acids bound to FFAR4. In this research, molecular structure-based machine-learning techniques were employed to evaluate compounds as potential agonists for FFAR4. Molecular structures were encoded into bit arrays, serving as molecular fingerprints, which were subsequently analyzed using the Bayesian network algorithm to identify patterns for screening the data. The shortlisted hits obtained via machine learning protocols …


Image De‑Photobombing Benchmark, Vatsa S. Patel, Kunal Agrawal, Samah Baraheem, Amira Yousif, Tam Nguyen Apr 2024

Image De‑Photobombing Benchmark, Vatsa S. Patel, Kunal Agrawal, Samah Baraheem, Amira Yousif, Tam Nguyen

Computer Science Faculty Publications

Removing photobombing elements from images is a challenging task that requires sophisticated image inpainting techniques. Despite the availability of various methods, their effectiveness depends on the complexity of the image and the nature of the distracting element. To address this issue, we conducted a benchmark study to evaluate 10 state-of-the-art photobombing removal methods on a dataset of over 300 images. Our study focused on identifying the most effective image inpainting techniques for removing unwanted regions from images. We annotated the photobombed regions that require removal and evaluated the performance of each method using peak signal-to-noise ratio (PSNR), structural similarity index …


Nowcasting Heavy Rainfall With Convolutional Long Short-Term Memory Networks: A Pixelwise Modeling Approach, Yi Victor Wang, Seung Hee Kim, Geunsu Lyu, Choeng-Lyong Lee, Soorok Ryu, Gyuwon Lee, Ki-Hong Min, Menas C. Kafatos Apr 2024

Nowcasting Heavy Rainfall With Convolutional Long Short-Term Memory Networks: A Pixelwise Modeling Approach, Yi Victor Wang, Seung Hee Kim, Geunsu Lyu, Choeng-Lyong Lee, Soorok Ryu, Gyuwon Lee, Ki-Hong Min, Menas C. Kafatos

Institute for ECHO Articles and Research

The recent decades have seen an increasing academic interest in leveraging machine learning approaches to nowcast, or forecast in a highly short-term manner, precipitation at a high resolution, given the limitations of the traditional numerical weather prediction models on this task. To capture the spatiotemporal associations of data on input variables, a deep learning (DL) architecture with the combination of a convolutional neural network and a recurrent neural network can be an ideal design for nowcasting rainfall. In this study, a long short-term memory (LSTM) modeling structure is proposed with convolutional operations on input variables. To resolve the issue of …


Cardiogpt: An Ecg Interpretation Generation Model, Guohua Fu, Jianwei Zheng, Islam Abudayyeh, Chizobam Ani, Cyril Rakovski, Louis Ehwerhemuepha, Hongxia Lu, Yongjuan Guo, Shenglin Liu, Huimin Chu, Bing Yang Apr 2024

Cardiogpt: An Ecg Interpretation Generation Model, Guohua Fu, Jianwei Zheng, Islam Abudayyeh, Chizobam Ani, Cyril Rakovski, Louis Ehwerhemuepha, Hongxia Lu, Yongjuan Guo, Shenglin Liu, Huimin Chu, Bing Yang

Mathematics, Physics, and Computer Science Faculty Articles and Research

Numerous supervised learning models aimed at classifying 12-lead electrocardiograms into different groups have shown impressive performance by utilizing deep learning algorithms. However, few studies are dedicated to applying the Generative Pre-trained Transformer (GPT) model in interpreting electrocardiogram (ECG) using natural language. Thus, we are pioneering the exploration of this uncharted territory by employing the CardioGPT model to tackle this challenge. We used a dataset of ECGs (standard 10s, 12-channel format) from adult patients, with 60 distinct rhythms or conduction abnormalities annotated by board-certified, actively practicing cardiologists. The ECGs were collected from The First Affiliated Hospital of Ningbo University and Shanghai …


Parallelized Quadtrees For Image Compression In Cuda And Mpi, Aidan Jones Apr 2024

Parallelized Quadtrees For Image Compression In Cuda And Mpi, Aidan Jones

Senior Honors Theses

Quadtrees are a data structure that lend themselves well to image compression due to their ability to recursively decompose 2-dimensional space. Image compression algorithms that use quadtrees should be simple to parallelize; however, current image compression algorithms that use quadtrees rarely use parallel algorithms. An existing program to compress images using quadtrees was upgraded to use GPU acceleration with CUDA but experienced an average slowdown by a factor of 18 to 42. Another parallelization attempt utilized MPI to process contiguous chunks of an image in parallel and experienced an average speedup by a factor of 1.5 to 3.7 compared to …


Piecing Together Performance: Collaborative, Participatory Research-Through-Design For Better Diversity In Games, Daniel L. Gardner, Louanne Boyd, Reginald T. Gardner Jan 2024

Piecing Together Performance: Collaborative, Participatory Research-Through-Design For Better Diversity In Games, Daniel L. Gardner, Louanne Boyd, Reginald T. Gardner

Engineering Faculty Articles and Research

Digital games are a multi-billion-dollar industry whose production and consumption extend globally. Representation in games is an increasingly important topic. As those who create and consume the medium grow ever more diverse, it is essential that player or user-experience research, usability, and any consideration of how people interface with their technology is exercised through inclusive and intersectional lenses. Previous research has identified how character configuration interfaces preface white-male defaults [39, 40, 67]. This study relies on 1-on-1 play-interviews where diverse participants attempt to create “themselves” in a series of games and on group design activities to explore how participants may …


Gnss Software Defined Radio: History, Current Developments, And Standardization Efforts, Thomas Pany, Dennis Akos, Javier Arribas, M. Zahidul H. Bhuiyan, Pau Closas, Fabio Dovis, Ignacio Fernandez-Hernandez, Carles Fernandez-Prades, Sanjeev Gunawardena, Todd Humphreys, Zaher M. Kassas, Jose A. Lopez Salcedo, Mario Nicola, Mario L. Psiaki, Alexander Rugamer, Yong-Jin Song, Jong-Hoon Won Jan 2024

Gnss Software Defined Radio: History, Current Developments, And Standardization Efforts, Thomas Pany, Dennis Akos, Javier Arribas, M. Zahidul H. Bhuiyan, Pau Closas, Fabio Dovis, Ignacio Fernandez-Hernandez, Carles Fernandez-Prades, Sanjeev Gunawardena, Todd Humphreys, Zaher M. Kassas, Jose A. Lopez Salcedo, Mario Nicola, Mario L. Psiaki, Alexander Rugamer, Yong-Jin Song, Jong-Hoon Won

Faculty Publications

Taking the work conducted by the global navigation satellite system (GNSS) software-defined radio (SDR) working group during the last decade as a seed, this contribution summarizes, for the first time, the history of GNSS SDR development. This report highlights selected SDR implementations and achievements that are available to the public or that influenced the general development of SDR. Aspects related to the standardization process of intermediate-frequency sample data and metadata are discussed, and an update of the Institute of Navigation SDR Standard is proposed. This work focuses on GNSS SDR implementations in general-purpose processors and leaves aside developments conducted on …


Predicting An Optimal Medication/Prescription Regimen For Patient Discordant Chronic Comorbidities Using Multi-Output Models, Ichchha Pradeep Sharma, Tam Nguyen, Shruti Ajay Singh, Tom Ongwere Jan 2024

Predicting An Optimal Medication/Prescription Regimen For Patient Discordant Chronic Comorbidities Using Multi-Output Models, Ichchha Pradeep Sharma, Tam Nguyen, Shruti Ajay Singh, Tom Ongwere

Computer Science Faculty Publications

This paper focuses on addressing the complex healthcare needs of patients struggling with discordant chronic comorbidities (DCCs). Managing these patients within the current healthcare system often proves to be a challenging process, characterized by evolving treatment needs necessitating multiple medical appointments and coordination among different clinical specialists. This makes it difficult for both patients and healthcare providers to set and prioritize medications and understand potential drug interactions. The primary motivation of this research is the need to reduce medication conflict and optimize medication regimens for individuals with DCCs. To achieve this, we allowed patients to specify their health conditions and …