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Full-Text Articles in Physical Sciences and Mathematics
Path-Finding Methodology For Visually-Impaired Patients Based On Image-Processing, Abhilash Goyal
Path-Finding Methodology For Visually-Impaired Patients Based On Image-Processing, Abhilash Goyal
Master's Projects
The objective of this project is to propose and develop the path-finding methodology for the visually impaired patients. The proposed novel methodology is based on image-processing and it is targeted for the patients who are not completely blind. The major problem faced by visually impaired patients is to walk independently. It is mainly because these patients can not see obstacles in front of them due to the degradation in their eye sight. Degradation in the eye-sight is mainly because either the light doesn't focus on the retina properly or due to the malfunction of the photoreceptor cells on the retina, …
Predicting Pancreatic Cancer Using Support Vector Machine, Akshay Bodkhe
Predicting Pancreatic Cancer Using Support Vector Machine, Akshay Bodkhe
Master's Projects
This report presents an approach to predict pancreatic cancer using Support Vector Machine Classification algorithm. The research objective of this project it to predict pancreatic cancer on just genomic, just clinical and combination of genomic and clinical data. We have used real genomic data having 22,763 samples and 154 features per sample. We have also created Synthetic Clinical data having 400 samples and 7 features per sample in order to predict accuracy of just clinical data. To validate the hypothesis, we have combined synthetic clinical data with subset of features from real genomic data. In our results, we observed that …
Web - Based Office Market, Manodivya Kathiravan
Web - Based Office Market, Manodivya Kathiravan
Master's Projects
People who work in an office often have different pools of resources that they want to exchange. They want to trade their resources/work(seller) with a person who wants that particular resource(buyer) and in return get another resource the buyer offers. These kind of exchanges are often called Barter-exchanges where an item is traded for another item without the involvement of actual money. An exchange is set to be complete when there is a match between an available item and a desired item. This exchange is called direct exchange. When an item desired by one user is made available through a …
Comparing Authentic And Cryptic 5’ Splice Sites Using Hidden Markov Models And Decision Trees, Pratikshya Mishra
Comparing Authentic And Cryptic 5’ Splice Sites Using Hidden Markov Models And Decision Trees, Pratikshya Mishra
Master's Projects
Splicing is the editing of the precursor mRNA produced during transcription. The mRNA contains a large number of nucleotides in the introns and exons which are spliced to remove the introns and bind the exons to produce the mature mRNA which is translated to generate proteins. Hence accurate splicing at 5’ and 3’ splice sites (authentic splice sites (AuthSS)) is of foremost importance. The 5’ and 3’ splice sites are characterized by consensus sequences. Eukaryotic genome also contains splice sites known as Cryptic Splice Sites (CSS) that match the consensus. But the CSS are activated only when there is a …
Application Of Computational Methods To Study The Selection Of Authentic And Cryptic Splice Sites, Tapomay Dey
Application Of Computational Methods To Study The Selection Of Authentic And Cryptic Splice Sites, Tapomay Dey
Master's Projects
Proteins are building blocks of the bodies of eukaryotes, and the process of synthesizing proteins from DNA is crucial for the good health of an organism [13]. However, some mutations in the DNA may disrupt the selection of 5’ or 3’ splice sites by a spliceosome. An important research question is whether the disruptions have a stochastic relation to the position of nucleotides in the vicinity of the known authentic and cryptic splice sites. This can be achieved by proving that the authentic and cryptic splice sites are intrinsically different. However, the behavior of the spliceosome is not accurately known. …
Influence Detection And Spread Estimation In Social Networks, Madhura Kaple
Influence Detection And Spread Estimation In Social Networks, Madhura Kaple
Master's Projects
A social network is an online platform, where people communicate and share information with each other. Popular social network features, which make them di erent from traditional communication platforms, are: following a user, re-tweeting a post, liking and commenting on a post etc. Many companies use various social networking platforms extensively as a medium for marketing their products. A xed amount of budget is alloted by the companies to maximize the positive in uence of their product. Every social network consists of a set of users (people) with connections between them. Each user has the potential to extend its in …
Computational Analysis Of Cryptic Splice Sites, Remya Mohanan
Computational Analysis Of Cryptic Splice Sites, Remya Mohanan
Master's Projects
DNA in the nucleus of all eukaryotes is transcribed into mRNA where it is then translated into proteins. The DNA which is transcribed into mRNA is composed of coding and non-coding regions called exons and introns, respectively. It undergoes a post-trancriptional process called splicing where the introns or the non-coding regions are removed from the pre-mRNA to give the mature mRNA. Splicing of pre-mRNAs at 5 ́ and 3ˊ ends is a crucial step in the gene expression pathway. The mis-splicing by the spliceosome at different sites known as cryptic splice sites is caused by mutations which will affect the …