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Full-Text Articles in Physical Sciences and Mathematics
Information Theoretic Thresholding Techniques Based On Particle Swarm Optimization., Surina Surina
Information Theoretic Thresholding Techniques Based On Particle Swarm Optimization., Surina Surina
Electronic Theses and Dissertations
In this dissertation, we discuss multi-level image thresholding techniques based on information theoretic entropies. In order to apply the correlation information of neighboring pixels of an image to obtain better segmentation results, we propose several multi-level thresholding models by using Gray-Level & Local-Average histogram (GLLA) and Gray-Level & Local-Variance histogram (GLLV). Firstly, a RGB color image thresholding model based on GLLA histogram and Tsallis-Havrda-Charv'at entropy is discussed. We validate the multi-level thresholding criterion function by using mathematical induction. For each component image, we assign the mean value from each thresholded class to obtain three segmented component images independently. Then we …
Evaluation Of Drug-Loaded Gold Nanoparticle Cytotoxicity As A Function Of Tumor Tissue Heterogeneity., Hunter Allan Miller
Evaluation Of Drug-Loaded Gold Nanoparticle Cytotoxicity As A Function Of Tumor Tissue Heterogeneity., Hunter Allan Miller
Electronic Theses and Dissertations
The inherent heterogeneity of tumor tissue presents a major challenge to nanoparticle-medicated drug delivery. This heterogeneity spans from the molecular to the cellular (cell types) and to the tissue (vasculature, extra-cellular matrix) scales. Here we employ computational modeling to evaluate therapeutic response as a function of vascular-induced tumor tissue heterogeneity. Using data with three-layered gold nanoparticles loaded with cisplatin, nanotherapy is simulated with different levels of tissue heterogeneity, and the treatment response is measured in terms of tumor regression. The results show that tumor vascular density non-trivially influences the nanoparticle uptake and washout, and the associated tissue response. The drug …
Developments In Multivariate Post Quantum Cryptography., Jeremy Robert Vates
Developments In Multivariate Post Quantum Cryptography., Jeremy Robert Vates
Electronic Theses and Dissertations
Ever since Shor's algorithm was introduced in 1994, cryptographers have been working to develop cryptosystems that can resist known quantum computer attacks. This push for quantum attack resistant schemes is known as post quantum cryptography. Specifically, my contributions to post quantum cryptography has been to the family of schemes known as Multivariate Public Key Cryptography (MPKC), which is a very attractive candidate for digital signature standardization in the post quantum collective for a wide variety of applications. In this document I will be providing all necessary background to fully understand MPKC and post quantum cryptography as a whole. Then, I …