Open Access. Powered by Scholars. Published by Universities.®
Physical Sciences and Mathematics Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 3 of 3
Full-Text Articles in Physical Sciences and Mathematics
Purification And Crystallization Of Cyclin-Dependent Kinase Inhibitor P21., D. Mayrose, Michael Nichols, Y. Xiong, H. Ke
Purification And Crystallization Of Cyclin-Dependent Kinase Inhibitor P21., D. Mayrose, Michael Nichols, Y. Xiong, H. Ke
Michael A Nichols
p21, a universal inhibitor of mammalian cyclin-dependent kinases (CDK), regulates cell cycle progression by forming various distinct protein complexes with cyclins, CDKs, and the proliferating cell nuclear antigen. We have overexpressed recombinant human p21 in E. coli and purified active p21 to near homogeneity on a large scale. Crystals of recombinant p21 have been grown in the space group P2(1) a = 157.4, b = 152.7, c = 90.6 A, and beta = 92.7 degrees. The diffraction data of the recombinant p21 have been collected to 2.5 and 3.5 A resolution for the native crystal and two heavy atom derivatives …
Hexameric Lithium Phenolate: Crystal Structures And Lithium-7 Quadrupole Coupling In Solid And Solution Phases., Lloyd Jackman, Deniz Cizmeciyan, Paul Willard, Michael Nichols
Hexameric Lithium Phenolate: Crystal Structures And Lithium-7 Quadrupole Coupling In Solid And Solution Phases., Lloyd Jackman, Deniz Cizmeciyan, Paul Willard, Michael Nichols
Michael A Nichols
No abstract provided.
Solid-State Structures Of N-Butyllithium-Tmeda, -Thf, And -Dme Complexes., Michael Nichols, Paul Williard
Solid-State Structures Of N-Butyllithium-Tmeda, -Thf, And -Dme Complexes., Michael Nichols, Paul Williard
Michael A Nichols
No abstract provided.