Physical Sciences and Mathematics Commons^™

Brain-Encysting Trematodes (Euhaplorchis Californiensis) Decrease Raphe Serotonergic Activity In California Killifish (Fundulus Parvipinnis), Siri H. Helland-Riise, Marco A. Vindas, Ida B. Johansen, Lauren E. Nadler, Kelly L. Weinersmith, Ryan F. Hechinger, Øyvind Øverli

Marine & Environmental Sciences Faculty Articles

Modulation of brain serotonin (5-HT) signalling is associated with parasite-induced changes in host behaviour, potentially increasing parasite transmission to predatory final hosts. Such alterations could have substantial impact on host physiology and behaviour, as 5-HT serves multiple roles in neuroendocrine regulation. These effects, however, remain insufficiently understood, as parasites have been associated with both increased and decreased serotonergic activity. Here, we investigated effects of trematode Euhaplorchis californiensis metacercariae on post-stress serotonergic activity in the intermediate host California killifish (Fundulus parvipinnis). This parasite is associated with conspicuous behaviour and increased predation of killifish by avian end-hosts, as well as …