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Physical Sciences and Mathematics Commons

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Full-Text Articles in Physical Sciences and Mathematics

Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen Jan 2024

Multiscale Modelling Of Brain Networks And The Analysis Of Dynamic Processes In Neurodegenerative Disorders, Hina Shaheen

Theses and Dissertations (Comprehensive)

The complex nature of the human brain, with its intricate organic structure and multiscale spatio-temporal characteristics ranging from synapses to the entire brain, presents a major obstacle in brain modelling. Capturing this complexity poses a significant challenge for researchers. The complex interplay of coupled multiphysics and biochemical activities within this intricate system shapes the brain's capacity, functioning within a structure-function relationship that necessitates a specific mathematical framework. Advanced mathematical modelling approaches that incorporate the coupling of brain networks and the analysis of dynamic processes are essential for advancing therapeutic strategies aimed at treating neurodegenerative diseases (NDDs), which afflict millions of …


Olfactory Bulb Processing Of Ortho Versus Retronasal Odors, Michelle F. Craft, Andrea Barreiro, Shree Gautam, Woodrow Shew, Cheng Ly May 2022

Olfactory Bulb Processing Of Ortho Versus Retronasal Odors, Michelle F. Craft, Andrea Barreiro, Shree Gautam, Woodrow Shew, Cheng Ly

Biology and Medicine Through Mathematics Conference

No abstract provided.


Spiking Activity In Networks Of Neurons Impacted By Axonal Swelling, Brian Frost, Stan Mintchev May 2019

Spiking Activity In Networks Of Neurons Impacted By Axonal Swelling, Brian Frost, Stan Mintchev

Biology and Medicine Through Mathematics Conference

No abstract provided.


Predicting Dynamics From Hardwiring In Canonical Low-Dimensional Coupled Networks, Anca R. Radulescu May 2019

Predicting Dynamics From Hardwiring In Canonical Low-Dimensional Coupled Networks, Anca R. Radulescu

Biology and Medicine Through Mathematics Conference

No abstract provided.


Timing Is Everything: Temporal Dynamics Of Brain Activity Using The Human Connectome Project, Francesca Lofaro Jan 2019

Timing Is Everything: Temporal Dynamics Of Brain Activity Using The Human Connectome Project, Francesca Lofaro

Summer Research

Most neuroimaging studies produce snapshots of brain activity. The goal of this project is to examine the temporal dynamics of how these areas interact through time, using fear as a case study to assess how regions involved in fear interact. Working with Matlab computer code, I sort through the large fMRI dataset known as the Human Connectome Project to extract neuroimaging data from patients with different NIH Toolbox Fear-Somatic survey scores to assess the temporal dynamics between brain regions. The results will allow an understanding beyond which areas are involved, and instead will provide a picture of how these areas …