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Full-Text Articles in Physical Sciences and Mathematics
Damped Oscillating Phosphoryl Transfer Reaction In The Cyanobacterial Circadian Clock, Hye In Jang, Pyonghwa Kim, Yongick Kim
Damped Oscillating Phosphoryl Transfer Reaction In The Cyanobacterial Circadian Clock, Hye In Jang, Pyonghwa Kim, Yongick Kim
Chemistry Faculty Research
Most organisms have circadian clocks to ensure the metabolic cycle to resonate with the rhythmic environmental changes without “damping,” or losing robustness. Cyanobacteria is the oldest and simplest form of life that is known to harbor this biological intricacy. Its KaiABC-based central oscillator proteins can be reconstituted inside a test tube, and the post-translational modification cycle occurs with 24 h periodicity. KaiC’s two major phosphorylation sites, Ser-431 and Thr-432, become phosphorylated and dephosphorylated by interacting with KaiA and KaiB, respectively. Here, we mutate Thr-432 into Ser to find the oscillatory phosphoryl transfer reaction damps. Previously, this mutant KaiC was reported …
Assessing Ecotoxicity Of Surface Water And Sediment In The Little Scioto River, Leah Suzanne Morgan
Assessing Ecotoxicity Of Surface Water And Sediment In The Little Scioto River, Leah Suzanne Morgan
Theses, Dissertations and Capstones
Aquatic toxicology evaluates the impact of pollution on freshwater and marine biota. Polycyclic aromatic hydrocarbons (PAHs) are one class of chemicals prevalent in the environment that impair aquatic organisms. This study examined the effect of contaminated surface water and sediments from a former wood treatment facility on four aquatic species: Pimephales promelas (fathead minnow), Ceriodaphnia dubia (water flea), Chironomus dilutus (midge), and Daphnia magna (water flea). The findings showed that sediment contamination had no significant effect on survival and growth of C. dilutus or on survival of D. magna. Surface water contamination began to have a significant effect on …