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Full-Text Articles in Physical Sciences and Mathematics

A Hybrid Agent-Based And Equation Based Model For The Spread Of Infectious Diseases, Elizabeth Hunter, Brian Mac Namee, John D. Kelleher Oct 2020

A Hybrid Agent-Based And Equation Based Model For The Spread Of Infectious Diseases, Elizabeth Hunter, Brian Mac Namee, John D. Kelleher

Articles

Both agent-based models and equation-based models can be used to model the spread of an infectious disease. Equation-based models have been shown to capture the overall dynamics of a disease outbreak while agent-based models are able to capture heterogeneous characteristics of agents that drive the spread of an outbreak. However, agent-based models are computationally intensive. To capture the advantages of both the equation-based and agent-based models, we create a hybrid model where the disease component of the hybrid model switches between agent-based and equation-based. The switch is determined using the number of agents infected. We first test the model at …


Epidemiology Of Cancers In Men Who Have Sex With Men (Msm): A Protocol For Umbrella Review Of Systematic Reviews, Manoj Kumar Honaryar, Yelena Tarasenko, Maribel Almonte, Vitaly Smelov Jul 2020

Epidemiology Of Cancers In Men Who Have Sex With Men (Msm): A Protocol For Umbrella Review Of Systematic Reviews, Manoj Kumar Honaryar, Yelena Tarasenko, Maribel Almonte, Vitaly Smelov

Department of Biostatistics, Epidemiology, and Environmental Health Sciences Faculty Publications

While earlier studies on men having sex with men (MSM) tended to examine infection-related cancers, an increasing number of studies have been focusing on effects of sexual orientation on other cancers and social and cultural causes for cancer disparities. As a type of tertiary research, this umbrella review (UR) aims to synthesize findings from existing review studies on the effects of sexual orientation on cancer. Relevant peer-reviewed systematic reviews (SRs) will be identified without date or language restrictions using MEDLINE, Cochrane Database of Systematic Reviews, and the International Prospective Register for Systematic Reviews, among others. The research team members will …


The Statistical Estimation Of The Basic Reproduction Number And Other Parameters Of Seir Stochastic Epidemic Models. Case Study- Influenza, Divine Wanduku May 2020

The Statistical Estimation Of The Basic Reproduction Number And Other Parameters Of Seir Stochastic Epidemic Models. Case Study- Influenza, Divine Wanduku

Biology and Medicine Through Mathematics Conference

No abstract provided.


The Role Of Diversity Amplification For Personal Protection Control Strategies In Vector-Borne Disease Models, Jeffery Demers, Sharon Bewick, Justin M. Calabrese, William F. Fagan May 2020

The Role Of Diversity Amplification For Personal Protection Control Strategies In Vector-Borne Disease Models, Jeffery Demers, Sharon Bewick, Justin M. Calabrese, William F. Fagan

Biology and Medicine Through Mathematics Conference

No abstract provided.


Searching For Superspreaders: Identifying Epidemic Patterns Associated With Superspreading Events In Stochastic Models, Omar Saucedo May 2020

Searching For Superspreaders: Identifying Epidemic Patterns Associated With Superspreading Events In Stochastic Models, Omar Saucedo

Biology and Medicine Through Mathematics Conference

No abstract provided.


Controlling Outbreaks Of Vector-Borne Disease On A Neighborhood Scale, Suzanne Robertson May 2020

Controlling Outbreaks Of Vector-Borne Disease On A Neighborhood Scale, Suzanne Robertson

Biology and Medicine Through Mathematics Conference

No abstract provided.


The Role Of Repeat Infection In The Dynamics Of A Simple Model Of Waning And Boosting Immunity, Laura F. Strube, Maya Walton, Lauren M. Childs May 2020

The Role Of Repeat Infection In The Dynamics Of A Simple Model Of Waning And Boosting Immunity, Laura F. Strube, Maya Walton, Lauren M. Childs

Biology and Medicine Through Mathematics Conference

No abstract provided.


Performance Of Phenomenological Models For Real-Time Forecasting The Covid-19 Epidemic, Kimberlyn Roosa, Gerardo Chowell May 2020

Performance Of Phenomenological Models For Real-Time Forecasting The Covid-19 Epidemic, Kimberlyn Roosa, Gerardo Chowell

Biology and Medicine Through Mathematics Conference

No abstract provided.


Using Network Modeling To Understand The Relationship Between Sars-Cov-1 And Sars-Cov-2, Elizabeth Brooke Haywood, Nicole A. Bruce May 2020

Using Network Modeling To Understand The Relationship Between Sars-Cov-1 And Sars-Cov-2, Elizabeth Brooke Haywood, Nicole A. Bruce

Biology and Medicine Through Mathematics Conference

No abstract provided.


Exploring The Effect Of The Nestling Recruitment Curve On Enzootic West Nile Virus Transmission, Emily B. Horton May 2020

Exploring The Effect Of The Nestling Recruitment Curve On Enzootic West Nile Virus Transmission, Emily B. Horton

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Model For The Spread Of Infectious Diseases In A Region, Elizabeth Hunter, Brian Mac Namee, John D. Kelleher Apr 2020

A Model For The Spread Of Infectious Diseases In A Region, Elizabeth Hunter, Brian Mac Namee, John D. Kelleher

Articles

In understanding the dynamics of the spread of an infectious disease, it is important to understand how a town’s place in a network of towns within a region will impact how the disease spreads to that town and from that town. In this article, we take a model for the spread of an infectious disease in a single town and scale it up to simulate a region containing multiple towns. The model is validated by looking at how adding additional towns and commuters influences the outbreak in a single town. We then look at how the centrality of a town …


Concordance Between Health Administrative Data And Survey-Derived Diagnoses For Mood And Anxiety Disorders, J. Edwards, A. Thind, S. Stranges, M. Chiu, Kelly K. Anderson Apr 2020

Concordance Between Health Administrative Data And Survey-Derived Diagnoses For Mood And Anxiety Disorders, J. Edwards, A. Thind, S. Stranges, M. Chiu, Kelly K. Anderson

Epidemiology and Biostatistics Publications

Objective: To assess whether estimates of survey structured interview diagnoses of mood and anxiety disorders were concordant with diagnoses of these disorders obtained from health administrative data.

Methods: All Ontario respondents to the 2012 Canadian Community Health Survey-Mental Health (CCHS-MH) were linked to health administrative databases at ICES (formerly known as the Institute for Clinical Evaluative Sciences). Survey structured interview diagnoses were compared with health administrative data diagnoses obtained using a standardized algorithm. We used modified Poisson regression analyses to assess whether socio-demographic factors were associated with concordance between the two measures.

Results: Of the 4157 Ontarians included in our …


Rickettsialpox – A Rare But Not Extinct Disease: A Review Of The Literature And New Directions, Marina Eremeeva, Kamalich Muniz-Rodriguez Jan 2020

Rickettsialpox – A Rare But Not Extinct Disease: A Review Of The Literature And New Directions, Marina Eremeeva, Kamalich Muniz-Rodriguez

Department of Biostatistics, Epidemiology, and Environmental Health Sciences Faculty Publications

Smallpox rickettsia is an urban zoonosis caused by Rickettsia akari. To date, R. akari is the only characterized representative of the group of spotted fevers transmitted by the gamasid mite Liponyssoides sanguineus, which is common among peridomic rodents. This disease was first described in New York in 1946, and a few years later a similar outbreak occurred in the Ukrainian SSR. Numerous serological studies and diagnostics of sporadic cases of smallpox rickettsiosis suggest its widespread occurrence on the planet; however, the current geography and incidence of smallpox rickettsiosis is unknown. Smallpox rickettsiosis is characterized by the classic clinical triad of …


On The Dynamics And Structure Of Multiple Strain Epidemic Models And Genotype Networks, Blake Joseph Mitchell Williams Jan 2020

On The Dynamics And Structure Of Multiple Strain Epidemic Models And Genotype Networks, Blake Joseph Mitchell Williams

Graduate College Dissertations and Theses

Mathematical disease modeling has long operated under the assumption that any one infectious disease is caused by one transmissible pathogen. This paradigm has been useful in simplifying the biological reality of epidemics and has allowed the modeling community to focus on the complexity of other factors such as contact structure and interventions. However, there is an increasing amount of evidence that the strain diversity of pathogens, and their interplay with the host immune system, can play a large role in shaping the dynamics of epidemics.

This body of work first explores the role of strain-transcending immunity in mathematical disease models, …